Seattle, Washington Clinical Trials

A listing of Seattle, Washington clinical trials actively recruiting patient volunteers.

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Found 70 clinical trials
A Study of Tirzepatide (LY3298176) Compared With Dulaglutide on Major Cardiovascular Events in Participants With Type 2 Diabetes

The purpose of the trial is to assess the efficacy and safety of tirzepatide to dulaglutide in participants with type 2 diabetes and increased cardiovascular risk.

cardiovascular disease
dulaglutide
tirzepatide
body mass index
VA Puget Sound Health Care System
 (4.7 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +650 other locations
NA-831 Atazanavir and Dexamethasone Combination Therapy for the Treatment of COVID-19 Infection

This Phase 2/3 trial evaluates four treatment strategies for non-critically ill hospitalized participants (not requiring ICU admission and/or mechanical ventilation) with SARS CoV-2 infection, in which participants will receive NA-831 or Atazanavir with or without Dexamethasone.

combination therapy
acute respiratory syndrome (sars)
intrauterine device (iud)
critical illness
dexamethasone
Coronavirus Research Institute-Testing Site
 (0.3 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +29 other locations
A Study of Lasmiditan (LY573144) Treatment in Children Aged 6 to 17 With Migraine

The reason for this study is to see if lasmiditan is safe and effective in children aged 6 to 17 with migraine. The study will last up to 20 weeks and may include up to 4 visits.

headache
ly573144
migraine
lasmiditan
treatment regimen
North Seattle Womens Group
 (4.8 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +162 other locations
Safety and Efficacy of 4 Investigational HSV 2 Vaccines in Adults With Recurrent Genital Herpes Caused by HSV 2

The primary objectives of the study are: To describe the safety profile of different investigational vaccine regimens against herpes simplex virus type 2 (HSV-2). To evaluate the efficacy of the investigational vaccine regimens with respect to: the frequency of herpes simplex virus (HSV) deoxyribonucleic acid (DNA) detection in the genital …

sodium chloride
antiviral therapy
herpes simplex
recurrent genital herpes
vaccination
Investigational Site Number 8400001
 (0.3 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +3 other locations
Cabozantinib With Radiation Therapy for the Treatment of Sarcomas of the Extremities

This phase I/II trial studies the side effects and best dose of cabozantinib when given with radiation therapy and how well it works in treating patients with sarcoma of the extremities. Cabozantinib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Giving …

g-csf
blood transfusion
gilbert's syndrome
serum pregnancy test
bone metastases
Fred Hutch/University of Washington Cancer Consortium
 (1.7 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location
Telehealth Pain Self-Management for Employed Adults

The E-TIPS trial will evaluate an evidence-based, telehealth pain self-management intervention compared to standard care (a waitlist) for chronic pain in adults with physical disabilities who are employed. Participants from anywhere in the US will be randomized to either E-TIPS, a cognitive-behavioral pain self-management intervention delivered by telephone, or a …

chronic pain
physical disability
University of Washington
 (0.3 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location
Testing the Addition of Radiotherapy to the Usual Treatment (Chemotherapy) for Patients With Esophageal and Gastric Cancer That Has Spread to a Limited Number of Other Places in the Body

This phase III trial studies how well the addition of radiotherapy to the usual treatment (chemotherapy) works compared to the usual treatment alone in treating patients with esophageal and gastric cancer that has spread to a limited number of other places in the body (oligometastatic disease). Radiotherapy uses high energy …

gastric cancer
fluorouracil
adenocarcinoma of esophagus
major surgery
oral contraceptives
Pacific Gynecology Specialists
 (0.3 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +254 other locations
Remote Ischemic Conditioning to Enhance Resuscitation (RICE) Pilot

Following resuscitation from out-of-hospital cardiac arrest (OHCA), reperfusion injury can cause cell damage in the heart and brain. Remote ischemic conditioning (RIC) consists of intermittent application of a device such as a blood pressure cuff to a limb to induce non-lethal ischemia. Studies in animals with cardiac arrest as well …

stemi
resuscitation
hypothermia
infarction
cardiac arrest
Graham Nichol
 (0.3 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location
Study to Evaluate Patients With Cerebrotendinous Xanthomatosis

The study is made up of two cohorts: a randomized double-blind crossover (placebo withdrawal with rescue) study among patients 16 years of age (adult cohort) and an open-label dose titration study among pediatric patients 1 month and <16 years of age (pediatric cohort)

Retrophin Investigational Site
 (3.3 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +1 other locations
A Study to Evaluate the Safety and Tolerability of Venetoclax Tablets in Combination With Capecitabine Tablets in Adult Participants With Hormone Receptor-Positive HER2-Negative Locally Advanced or Metastatic Breast Cancer Who Had Disease Progression During or After CDK4/6 Inhibitor Therapy

Endocrine therapy is the initial treatment for most hormone receptor positive (HR+), human epidermal growth factor receptor 2 negative (HER2-) breast cancers. This study will evaluate the use of venetoclax in combination with capecitabine in adult participants with HR+, HER2-, metastatic breast cancer (MBC) who had disease progression following treatment …

endocrine therapy
capecitabine
epidermal growth factor
growth factor
breast cancer
Swedish Cancer Institute /ID# 216120
 (0.3 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +15 other locations