Kirkland, Washington Clinical Trials

A listing of Kirkland, Washington clinical trials actively recruiting patient volunteers.

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Found 67 clinical trials
A Study to Evaluate the Efficacy and Safety of JCAR017 in Adult Subjects With Relapsed or Refractory Indolent B-cell Non-Hodgkin Lymphoma (NHL)

This is a global Phase 2, open-label, single-arm, multicohort, multicenter study to evaluate efficacy and safety of JCAR017 in adult subjects with r/r FL or MZL. The study will be conducted in compliance with the International Council on Harmonisation (ICH) of Technical Requirements for Registration of Pharmaceuticals for Human Use/Good …

cyclophosphamide
b-cell lymphoma
marginal zone lymphoma
hodgkin's disease
follicular lymphoma
Fred Hutchinson Cancer Research Center
 (7.3 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +35 other locations
Capivasertib+Abiraterone as Treatment for Patients With Metastatic Hormone-sensitive Prostate Cancer and PTEN Deficiency

This study will assess the efficacy and safety of capivasertib plus abiraterone (+prednisone/prednisolone) plus androgen deprivation therapy (ADT) versus placebo plus abiraterone (+prednisone/prednisolone) plus ADT in participants with mHSPC whose tumours are characterised by PTEN deficiency. The intention of the study is to demonstrate that in participants with mHSPC, the …

soft tissue lesion
bone lesion
gonadotropin releasing hormone
fatigue
luteinizing hormone-releasing hormone agonist
Research Site
 (7.8 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +106 other locations
A Study to Evaluate the Efficacy and Safety of Intravenous Prasinezumab in Participants With Early Parkinson's Disease  

This is a multicenter, randomized, double-blind, placebo-controlled study that will evaluate the efficacy and safety of intravenous (IV) prasinezumab versus placebo in participants with Early Parkinson's Disease (PD) who are on stable symptomatic PD medication.

dopamine
bradykinesia
dopamine transporter
early parkinson's
resting tremor
Evergreen Health Care Center
 (2.6 away)
  • 0 views
  • 28 Jun, 2022
  • +125 other locations
A Study of Tucatinib vs. Placebo in Combination With Ado-trastuzumab Emtansine (T-DM1) for Patients With Advanced or Metastatic HER2+ Breast Cancer

This study is being done to see if tucatinib with ado-trastuzumab emtansine (T-DM1) works better than T-DM1 alone to help patients who have a specific type of breast cancer called HER2 positive breast carcinoma. The breast cancer in this study is either metastatic (spread into other parts of the body) …

Swedish Cancer Institute
 (7.8 away) Contact site
  • 0 views
  • 14 Mar, 2022
  • +227 other locations
Rectal Versus Oral Diazepam Administration in the Treatment of Levator Ani Syndrome

This research involves collecting data about levator ani syndrome (LAS) associated rectal pain and a comparison of diazepam treatment administration routes. The goal of this research is to see if an alternative route of diazepam administration provides sufficient control of LAS discomfort and low sleep quality while minimizing systemic effects …

Swedish Medical Center Colon Rectal Clinic
 (7.8 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location
At-Risk for Type 1 Diabetes Extension Study

This study is an extension of the NIH-sponsored AT-Risk (TN-10) type 1 diabetes study (NCT 01030861). Teplizumab-treated and placebo-treated participants in the NIH trial who develop clinical type 1 diabetes after the conclusion of that trial, are eligible to enroll and receive teplizumab treatment within one year of diagnosis of …

diabetes
teplizumab
type 1 diabetes mellitus
Clinical site
 (7.7 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +4 other locations
Vaccine Responsiveness After CAR-T Cell Therapy

This phase I trial will use the inactivated rabies virus vaccine to assess immune function in patients who previously underwent B cell targeted chimeric antigen receptor-modified T cell immunotherapy (CARTx). A cohort of healthy volunteers will also be enrolled as a comparator group. CARTx is a new treatment for patients …

cell therapy
platelet count
biospecimen collection
cancer
infection prevention
Fred Hutch/University of Washington Cancer Consortium
 (7.3 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location
A Study of LY3819253 (LY-CoV555) in Participants With Mild to Moderate COVID-19 Illness

The purpose of this study is to measure how well LY3819253 works against the virus that causes COVID-19. LY3819253 will be given to participants with early symptoms of COVID-19, via an injection into a vein. Samples will be taken from the back of the nose to determine how much virus …

headache
respiratory disorder
sore throat
body mass index
intermittent positive pressure ventilation
Evergreen Health Research
 (2.6 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +61 other locations
Influence of Cooling Duration on Efficacy in Cardiac Arrest Patients

A multicenter, randomized, adaptive allocation clinical trial to determine if increasing durations of induced hypothermia are associated with an increasing rate of good neurological outcomes and to identify the optimal duration of induced hypothermia for neuroprotection in comatose survivors of cardiac arrest.

cardiac arrest
life support
coma
induced hypothermia
resuscitation
Harborview Medical Center
 (7.8 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +12 other locations
NA-831 Atazanavir and Dexamethasone Combination Therapy for the Treatment of COVID-19 Infection

This Phase 2/3 trial evaluates four treatment strategies for non-critically ill hospitalized participants (not requiring ICU admission and/or mechanical ventilation) with SARS CoV-2 infection, in which participants will receive NA-831 or Atazanavir with or without Dexamethasone.

intrauterine device (iud)
mechanical ventilation
covid-19
g6pd
dexamethasone
Coronavirus Research Institute-Testing Site
 (2.6 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +29 other locations