McLean, Virginia Clinical Trials

A listing of McLean, Virginia clinical trials actively recruiting patient volunteers.

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Found 75 clinical trials
Study to Evaluate the Safety and Efficacy of ATYR1923 In Patients With Severe Pneumonia Related to COVID-19

A Phase 2 study to evaluate the safety and preliminary efficacy of ATYR1923, compared to placebo, in hospitalized patients with SARS-CoV-2 (COVID-19) severe pneumonia not requiring mechanical ventilation

Inova Fairfax Medical Campus
 (4.7 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +4 other locations
Test-Trial-29-Aug  

Intense stress has harmful effects on the body, contributing to various disorders. Breast cancer patients experience a build-up of stress due to their diagnosis and treatments. Stress can cause epigenetic changes in a cellular level (such as accelerated increase in biological age) that may negatively affect oncological treatments.This study aims …

Georgetown University Medical Center Department of Neurology, 7PHC
 (6.2 away)
  • 0 views
  • 08 Sep, 2023
  • 1 location
A Study of Tirzepatide (LY3298176) Compared With Dulaglutide on Major Cardiovascular Events in Participants With Type 2 Diabetes

The purpose of the trial is to assess the efficacy and safety of tirzepatide to dulaglutide in participants with type 2 diabetes and increased cardiovascular risk.

dulaglutide
body mass index
tirzepatide
cardiovascular disease
Virginia Heart
 (4.7 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +650 other locations
Durvalumab With or Without Olaparib as Maintenance Therapy After First-Line Treatment of Advanced and Recurrent Endometrial Cancer

A study to assess the efficacy and safety of durvalumab in combination with platinum-based chemotherapy (paclitaxel + carboplatin) followed by maintenance durvalumab with or without olaparib for patients with newly diagnosed advanced or recurrent endometrial cancer.

olaparib
immunomodulators
carboplatin
adjuvant
sarcoma
Research Site
 (6.5 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +94 other locations
A Study of Donanemab (LY3002813) in Participants With Early Alzheimer's Disease (TRAILBLAZER-ALZ 2)

The reason for this study is to see how safe and effective the study drug donanemab is in participants with early Alzheimer's disease.

positron emission tomography
florbetapir
alzheimer's disease
flortaucipir
mini-mental state examination
Georgetown University Medical Center
 (7.7 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +85 other locations
NA-831 Atazanavir and Dexamethasone Combination Therapy for the Treatment of COVID-19 Infection

This Phase 2/3 trial evaluates four treatment strategies for non-critically ill hospitalized participants (not requiring ICU admission and/or mechanical ventilation) with SARS CoV-2 infection, in which participants will receive NA-831 or Atazanavir with or without Dexamethasone.

complete blood count
cervical cap
combination therapy
electrocardiogram (ecg)
acute respiratory syndrome (sars)
Coronavirus Research Institute-Testing Site
 (6.4 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +29 other locations
Selinexor (KPT-330) in Combination With Temozolomide and Radiation Therapy in Patients With Newly Diagnosed Glioblastoma

Background Glioblastoma is a type of brain cancer. Treatments include radiation, chemotherapy, and surgery. But survival rates are poor. Researchers think that the drug selinexor, when combined with chemotherapy and radiation, might help. Objective To learn the highest dose of selinexor that people with brain cancer can tolerate when given …

temodar
blood transfusion
ct scan
glioblastoma multiforme
blood test
National Institutes of Health Clinical Center
 (6.4 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location
Metarrestin (ML-246) in Subjects With Metastatic Solid Tumors

Background Metastasis is the spread of cancer from one organ to a nonadjacent organ. It causes 90% of cancer deaths. No treatment specifically prevents or reduces metastasis. Researchers hope a new drug can help. It stops cancer cells from growing and spreading further and possibly shrink cancer lesions in distant …

blood transfusion
ct scan
renal function
blood test
MRI
National Institutes of Health Clinical Center
 (6.4 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location
Treatment of Moderate to Severe Lateral Canthal Lines and Glabellar Lines Alone or in Combination

This study is designed to evaluate the safety and efficacy of a single dose of QM1114-DP for the treatment of moderate to severe LCL and moderate to severe GL, alone or in combination.

Washington Institute of Dermatologic Laser Surgery
 (6.7 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +9 other locations
SPRINT Peripheral Nerve Stimulation for the Treatment of Back Pain

The purpose of this study is to compare standard of care treatments for back pain to electrical stimulation. Electrical stimulation is delivering small amounts of electricity to the nerves in your low back. This study will use a device called the SPRINT Peripheral Nerve Stimulation (PNS) System. The SPRINT PNS …

peripheral nerve stimulation
back pain
electrical stimulation
chronic pain
low back pain
International Spine, Pain & Performance Center
 (7.7 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +1 other locations