Havertown, Pennsylvania Clinical Trials

A listing of Havertown, Pennsylvania clinical trials actively recruiting patient volunteers.

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Found 108 clinical trials
Study of AMG 509 in Subjects With Metastatic Castration-Resistant Prostate Cancer

Evaluate the safety and tolerability of AMG 509 in adult subjects and determine the maximum tolerated dose (MTD) or recommended phase 2 dose (RP2D).

renal function tests
bilateral orchidectomy
progressive disease
platelet count
growth factor
Research Site
 (8.2 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +3 other locations
Niraparib/TTFields in GBM

Evaluating the efficacy and safety of niraparib and Tumor-Treating Fields (TTFields) in recurrent glioblastoma (GBM).

karnofsky performance status
glioblastoma
renal function test
niraparib
renal function
Hospital of the University of Pennsylvania
 (6.2 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location
A Study of SY 5609 a Selective CDK7 Inhibitor in Advanced Solid Tumors

This is a dose escalation study and will be the first to administer SY-5609 alone to humans with select advanced solid tumors and in combination with Fulvestrant to patients with HR positive, HER2-negative breast cancer.

endocrine therapy
screening procedures
HER2
hair thinning
stage iv breast cancer
Sidney Kimmel Cancer Center
 (8.2 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +4 other locations
Testing the Addition of Radiotherapy to the Usual Treatment (Chemotherapy) for Patients With Esophageal and Gastric Cancer That Has Spread to a Limited Number of Other Places in the Body

This phase III trial studies how well the addition of radiotherapy to the usual treatment (chemotherapy) works compared to the usual treatment alone in treating patients with esophageal and gastric cancer that has spread to a limited number of other places in the body (oligometastatic disease). Radiotherapy uses high energy …

absolute neutrophil count
oral contraceptives
clinical stage ivb gastric cancer ajcc v8
major surgery
stomach neoplasm
Lankenau Medical Center
 (1.9 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +254 other locations
Reducing Emergency Department Visits and Improving Glucose Control in Uncontrolled Type 2 Diabetes Using CGM Sensors at Hospital Discharge

Quality measures and cost-reduction methods are a high priority in the United States health care system. This includes the high burden of patients with uncontrolled Type 2 Diabetes. Innovative ways to better understand and implement diabetes management plans to reduce the burden of this disease on the system are a …

continuous glucose monitoring
Albert Einstein Medical Center
 (9.7 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location
A Study to Evaluate the Safety and Tolerability of Venetoclax Tablets in Combination With Capecitabine Tablets in Adult Participants With Hormone Receptor-Positive HER2-Negative Locally Advanced or Metastatic Breast Cancer Who Had Disease Progression During or After CDK4/6 Inhibitor Therapy

Endocrine therapy is the initial treatment for most hormone receptor positive (HR+), human epidermal growth factor receptor 2 negative (HER2-) breast cancers. This study will evaluate the use of venetoclax in combination with capecitabine in adult participants with HR+, HER2-, metastatic breast cancer (MBC) who had disease progression following treatment …

endocrine therapy
HER2
erbb2
stage iv breast cancer
growth factor
University of Pennsylvania /ID# 216357
 (6.2 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +15 other locations
Phase 2 Trial of CD19 Redirected Autologous T Cells

This is an open-label, four-cohort, phase 2 study to determine the efficacy of CART19 in pediatric and young adult patientswith hypodiploid (Cohort A) or t(17;19) B-ALL (Cohort B), infants with very high risk KMT2A B-ALL (Cohort C), and in patients with central nervous system (CNS) relapse who did not receive …

Children's Hospital of Philadelphia
 (6.2 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location
Tipifarnib for the Treatment of Advanced Solid Tumors Lymphoma or Histiocytic Disorders With HRAS Gene Alterations a Pediatric MATCH Treatment Trial

This phase II pediatric MATCH trial studies how well tipifarnib works in treating patients with solid tumors that have spread to other places in the body (advanced), lymphoma, or histiocytic disorders that have HRAS genetic alterations. Tipifarnib may block the growth of cancer cells that have specific genetic changes in …

refractory non-hodgkin lymphoma
anti-cancer agents
recurrent osteosarcoma
cancer treatment
cancer therapy
Children's Hospital of Philadelphia
 (6.2 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +82 other locations
Phase 2 Clinical Trial of Crizotinib for Children and Adults With Neurofibromatosis Type 2 and Progressive Vestibular Schwannomas

Subjects with Neurofibromatosis Type 2 (NF2) and progressive vestibular schwannoma (VS) will be treated with crizotinib administered orally. Crizotinib will be taken continuously until disease progression or unacceptable toxicity, in continuous treatment cycles of 28 days each, for a maximum of 12 cycles.

neurofibroma
cataract
schwartz
measurable disease
nf2 gene
Children's Hospital of Philadelphia (Site 750)
 (1.9 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +16 other locations
Multicenter Clinical Trial of a Phakic Implantable Collamer Lens (ICL)

This objective of this study is to evaluate the safety, and to collect supportive data on effectiveness of the EVO/EVO+ Visian Implantable Collamer Lens (ICL) in study participants who have a diagnosis of myopia or myopia with astigmatism. Primary study analysis will be evaluated when 300 primary eyes complete 6 …

severe myopia
astigmatism
myopia
Kremer Eye Center
 (8.9 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +13 other locations