Drexel Hill, Pennsylvania Clinical Trials

A listing of Drexel Hill, Pennsylvania clinical trials actively recruiting patient volunteers.

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Found 102 clinical trials
Convalescent Plasma for the Treatment of COVID-19

This protocol provides access to investigational convalescent plasma for patients in acute care facilities infected with SARS-CoV-2 who have severe or life-threatening COVID-19, or who are judged by a healthcare provider to be at high risk of progression to severe or life-threatening disease. Following provision of informed consent, patients will …

covid-19
respiratory failure
FIO2
fraction of inspired oxygen (fio2)
shock
Thomas Jefferson University Hospital
 (7.7 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location
Acalabrutinib Study With Best Supportive Care Versus Best Supportive Care in Subjects Hospitalized With COVID-19.

CALAVI US will investigate the safety, efficacy and pharmacokinetics of acalabrutinib together with Best Supportive Care in the treatment of COVID-19.

covid-19
SARS
oximetry
acalabrutinib
pneumonia
Research Site
 (9.2 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +9 other locations
Cyclosporine in Patients With Moderate COVID-19

Phase 1 safety study to determine the tolerability, clinical effects, and changes in laboratory parameters of short course oral or IV cyclosporine (CSA) administration in patients with COVID-19 disease requiring oxygen supplementation but not requiring ventilator support.

covid-19
SARS
cyclosporin a
cyclosporine
oxygen supplementation
University of Pennsylvania
 (5.8 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location
Open-label Study to Determine the Maximum Tolerated Dose of DSG3-CAART in Mucosal-dominant PV Patients (mPV)

Mucosal-dominant pemphigus vulgaris (mPV) is a B-cell mediated autoimmune disorder in which painful blisters are formed on the mucosal membrane, including the mouth, nose, throat, eyelids, anus, and genitals. This phase 1 study is being conducted to find the maximum tolerated dose and optimal fractionated infusion schedule of an investigational …

University of Pennsylvania
 (5.8 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location
A Study of LY3819253 (LY-CoV555) in Participants With Mild to Moderate COVID-19 Illness

The purpose of this study is to measure how well LY3819253 works against the virus that causes COVID-19. LY3819253 will be given to participants with early symptoms of COVID-19, via an injection into a vein. Samples will be taken from the back of the nose to determine how much virus …

headache
respiratory disorder
sore throat
body mass index
intermittent positive pressure ventilation
Jefferson Hosp for Neurosci
 (7.7 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +61 other locations
COVID-19 Convalescent Plasma for Mechanically Ventilated Population

The purpose of this study is to see if this plasma can be safely used in humans with COVID-19 and to see if it can improve patients' health when they are sick with COVID-19.

mechanical ventilation
covid-19
x-rays
chest x-ray
ct scan
Hospital of the University of Pennsylvania
 (5.8 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location
Influence of Cooling Duration on Efficacy in Cardiac Arrest Patients

A multicenter, randomized, adaptive allocation clinical trial to determine if increasing durations of induced hypothermia are associated with an increasing rate of good neurological outcomes and to identify the optimal duration of induced hypothermia for neuroprotection in comatose survivors of cardiac arrest.

cardiac arrest
life support
coma
induced hypothermia
resuscitation
Temple University Hospital
 (9.2 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +12 other locations
A Study of Tirzepatide (LY3298176) Compared With Dulaglutide on Major Cardiovascular Events in Participants With Type 2 Diabetes

The purpose of the trial is to assess the efficacy and safety of tirzepatide to dulaglutide in participants with type 2 diabetes and increased cardiovascular risk.

dulaglutide
tirzepatide
body mass index
cardiovascular disease
Thomas Jefferson University
 (7.7 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +650 other locations
A Study of Donanemab (LY3002813) in Participants With Early Alzheimer's Disease (TRAILBLAZER-ALZ 2)

The reason for this study is to see how safe and effective the study drug donanemab is in participants with early Alzheimer's disease.

positron emission tomography
mini-mental state examination
florbetapir
flortaucipir
alzheimer's disease
University of Pennsylvania Heath System
 (5.8 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +85 other locations
A Phase 3 Study to Evaluate Efficacy and Safety of AL001 in Frontotemporal Dementia (INFRONT-3)

A phase 3 double blind, placebo controlled study evaluating the efficacy and safety of AL001 in participants at risk for or with frontotemporal dementia due to heterozygous mutations in the progranulin gene.

progranulin
aphasia
dementia
pick's disease
University of Pennsylvania
 (5.8 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +46 other locations