Bryn Mawr, Pennsylvania Clinical Trials

A listing of Bryn Mawr, Pennsylvania clinical trials actively recruiting patient volunteers.

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Found 95 clinical trials
Acalabrutinib Study With Best Supportive Care Versus Best Supportive Care in Subjects Hospitalized With COVID-19.

CALAVI US will investigate the safety, efficacy and pharmacokinetics of acalabrutinib together with Best Supportive Care in the treatment of COVID-19.

covid-19
SARS
oximetry
acalabrutinib
pneumonia
Research Site
 (9.6 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +9 other locations
Cyclosporine in Patients With Moderate COVID-19

Phase 1 safety study to determine the tolerability, clinical effects, and changes in laboratory parameters of short course oral or IV cyclosporine (CSA) administration in patients with COVID-19 disease requiring oxygen supplementation but not requiring ventilator support.

covid-19
SARS
oxygen supplementation
estimated creatinine clearance
cyclosporin a
University of Pennsylvania
 (8.4 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location
Open-label Study to Determine the Maximum Tolerated Dose of DSG3-CAART in Mucosal-dominant PV Patients (mPV)

Mucosal-dominant pemphigus vulgaris (mPV) is a B-cell mediated autoimmune disorder in which painful blisters are formed on the mucosal membrane, including the mouth, nose, throat, eyelids, anus, and genitals. This phase 1 study is being conducted to find the maximum tolerated dose and optimal fractionated infusion schedule of an investigational …

University of Pennsylvania
 (8.4 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location
A Study of LY3819253 (LY-CoV555) in Participants With Mild to Moderate COVID-19 Illness

The purpose of this study is to measure how well LY3819253 works against the virus that causes COVID-19. LY3819253 will be given to participants with early symptoms of COVID-19, via an injection into a vein. Samples will be taken from the back of the nose to determine how much virus …

sore throat
chronic obstructive pulmonary disease
immunosuppressive agents
lung disease
cardiovascular disease
Temple University Hospital
 (9.6 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +61 other locations
COVID-19 Convalescent Plasma for Mechanically Ventilated Population

The purpose of this study is to see if this plasma can be safely used in humans with COVID-19 and to see if it can improve patients' health when they are sick with COVID-19.

ct scan
mechanical ventilation
pneumonia
covid-19
SARS
Hospital of the University of Pennsylvania
 (8.4 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location
Influence of Cooling Duration on Efficacy in Cardiac Arrest Patients

A multicenter, randomized, adaptive allocation clinical trial to determine if increasing durations of induced hypothermia are associated with an increasing rate of good neurological outcomes and to identify the optimal duration of induced hypothermia for neuroprotection in comatose survivors of cardiac arrest.

resuscitation
cardiac arrest
induced hypothermia
hypothermia
life support
Temple University Hospital
 (9.6 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +12 other locations
A Study of Donanemab (LY3002813) in Participants With Early Alzheimer's Disease (TRAILBLAZER-ALZ 2)

The reason for this study is to see how safe and effective the study drug donanemab is in participants with early Alzheimer's disease.

florbetapir
flortaucipir
mini-mental state examination
alzheimer's disease
positron emission tomography
Keystone Clinical Studies
 (7.1 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +85 other locations
A Phase 3 Study to Evaluate Efficacy and Safety of AL001 in Frontotemporal Dementia (INFRONT-3)

A phase 3 double blind, placebo controlled study evaluating the efficacy and safety of AL001 in participants at risk for or with frontotemporal dementia due to heterozygous mutations in the progranulin gene.

progranulin
dementia
pick's disease
aphasia
University of Pennsylvania
 (8.4 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +46 other locations
NA-831 Atazanavir and Dexamethasone Combination Therapy for the Treatment of COVID-19 Infection

This Phase 2/3 trial evaluates four treatment strategies for non-critically ill hospitalized participants (not requiring ICU admission and/or mechanical ventilation) with SARS CoV-2 infection, in which participants will receive NA-831 or Atazanavir with or without Dexamethasone.

critical illness
dexamethasone
electrocardiogram (ecg)
intrauterine device (iud)
cervical cap
Coronavirus Research Institute-Testing Site
 (8.4 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +29 other locations
V6.3 Additional &QA123  

Test Comment here

Hospital of the University of Pennsylvania-AUS
 (9.9 away)
  • 0 views
  • 24 Aug, 2023
  • +3 other locations