Broomall, Pennsylvania Clinical Trials

A listing of Broomall, Pennsylvania clinical trials actively recruiting patient volunteers.

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Found 80 clinical trials
A Phase 2 Trial of Multiple Myeloma  

A Phase 2 Trial of Multiple Myeloma

Hospital of the University of Pennsylvania
 (8.8 away)
  • 0 views
  • 11 Nov, 2025
  • 1 location
Anti-GITR/Anti-PD1/Stereotactic Radiosurgery in Recurrent Glioblastoma

This is a phase II study of the combination of the GITR agonist monoclonal antibody INCAGN01876, the anti-PD1 monoclonal antibody INCMGA00012, and stereotactic radiosurgery (SRS) for recurrent Glioblastoma (GBM). The investigators hypothesize that the proposed regimen will be safe and stimulate a robust anti-tumor immune response and result in improved …

astrocytoma
absolute lymphocyte count
PCR test
bevacizumab
cytotoxic chemotherapy
Hospital of the University of Pennsylvania
 (8.8 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location
Reduced Radiation Dose and IR-impact on Coronary Calcium Quantification

Evaluation of reduced radiation dose iterative reconstruction reconstructions for calcium scoring compared to full dose filtered back projection reconstructions

University of Pennsylvania
 (8.8 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location
Treatment of BK Virus Infection With CTL Cells in Immunocompromised Transplant Patients

This is a pilot study using cytotoxic T lymphocytes (CTLs) manufactured with the Miltenyi CliniMACS Prodigy Gamma-capture system will be effective in decreasing specific viral load in patients with BK virus viremia and BK virus-associated symptoms post-allogeneic hematopoietic stem cell transplantation (HSCT), renal transplantation, and chemotherapy.

Children's Hospital of Philadelphia
 (8.8 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location
Cyclosporine in Patients With Moderate COVID-19

Phase 1 safety study to determine the tolerability, clinical effects, and changes in laboratory parameters of short course oral or IV cyclosporine (CSA) administration in patients with COVID-19 disease requiring oxygen supplementation but not requiring ventilator support.

SARS
acute respiratory syndrome (sars)
oxygen supplementation
covid-19
cyclosporin a
University of Pennsylvania
 (8.8 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location
Open-label Study to Determine the Maximum Tolerated Dose of DSG3-CAART in Mucosal-dominant PV Patients (mPV)

Mucosal-dominant pemphigus vulgaris (mPV) is a B-cell mediated autoimmune disorder in which painful blisters are formed on the mucosal membrane, including the mouth, nose, throat, eyelids, anus, and genitals. This phase 1 study is being conducted to find the maximum tolerated dose and optimal fractionated infusion schedule of an investigational …

University of Pennsylvania
 (8.8 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location
COVID-19 Convalescent Plasma for Mechanically Ventilated Population

The purpose of this study is to see if this plasma can be safely used in humans with COVID-19 and to see if it can improve patients' health when they are sick with COVID-19.

pneumonia
chest x-ray
mechanical ventilation
x-rays
acute respiratory syndrome (sars)
Hospital of the University of Pennsylvania
 (8.8 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location
A Study of Donanemab (LY3002813) in Participants With Early Alzheimer's Disease (TRAILBLAZER-ALZ 2)

The reason for this study is to see how safe and effective the study drug donanemab is in participants with early Alzheimer's disease.

flortaucipir
mini-mental state examination
florbetapir
alzheimer's disease
positron emission tomography
University of Pennsylvania Heath System
 (8.8 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +85 other locations
A Phase 3 Study to Evaluate Efficacy and Safety of AL001 in Frontotemporal Dementia (INFRONT-3)

A phase 3 double blind, placebo controlled study evaluating the efficacy and safety of AL001 in participants at risk for or with frontotemporal dementia due to heterozygous mutations in the progranulin gene.

pick's disease
progranulin
aphasia
dementia
University of Pennsylvania
 (8.8 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +46 other locations
NA-831 Atazanavir and Dexamethasone Combination Therapy for the Treatment of COVID-19 Infection

This Phase 2/3 trial evaluates four treatment strategies for non-critically ill hospitalized participants (not requiring ICU admission and/or mechanical ventilation) with SARS CoV-2 infection, in which participants will receive NA-831 or Atazanavir with or without Dexamethasone.

combination therapy
mechanical ventilation
critical illness
electrocardiogram (ecg)
dexamethasone
Coronavirus Research Institute-Testing Site
 (8.8 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +29 other locations