Bala Cynwyd, Pennsylvania Clinical Trials

A listing of Bala Cynwyd, Pennsylvania clinical trials actively recruiting patient volunteers.

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Found 119 clinical trials
Phase I Study in Advanced Malignancies

RDT aims to take advantage of the relatively safer toxicity profiles of both lower dose radiation therapy and systemic ALA to treat non-superficial lesions in a manner similar to photodynamic therapy. The doses of radiation administered in this study will be lower than those typically used to treat cancer. However, …

solid neoplasm
experimental therapy
growth factor
solid tumor
serum total bilirubin level
Fox Chase Cancer Center
 (8.9 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location
Acalabrutinib Study With Best Supportive Care Versus Best Supportive Care in Subjects Hospitalized With COVID-19.

CALAVI US will investigate the safety, efficacy and pharmacokinetics of acalabrutinib together with Best Supportive Care in the treatment of COVID-19.

covid-19
SARS
oximetry
acalabrutinib
pneumonia
Research Site
 (4.5 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +9 other locations
Cyclosporine in Patients With Moderate COVID-19

Phase 1 safety study to determine the tolerability, clinical effects, and changes in laboratory parameters of short course oral or IV cyclosporine (CSA) administration in patients with COVID-19 disease requiring oxygen supplementation but not requiring ventilator support.

covid-19
SARS
oxygen supplementation
estimated creatinine clearance
cyclosporin a
University of Pennsylvania
 (4.2 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location
Open-label Study to Determine the Maximum Tolerated Dose of DSG3-CAART in Mucosal-dominant PV Patients (mPV)

Mucosal-dominant pemphigus vulgaris (mPV) is a B-cell mediated autoimmune disorder in which painful blisters are formed on the mucosal membrane, including the mouth, nose, throat, eyelids, anus, and genitals. This phase 1 study is being conducted to find the maximum tolerated dose and optimal fractionated infusion schedule of an investigational …

University of Pennsylvania
 (4.2 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location
A Study of LY3819253 (LY-CoV555) in Participants With Mild to Moderate COVID-19 Illness

The purpose of this study is to measure how well LY3819253 works against the virus that causes COVID-19. LY3819253 will be given to participants with early symptoms of COVID-19, via an injection into a vein. Samples will be taken from the back of the nose to determine how much virus …

sore throat
chronic obstructive pulmonary disease
immunosuppressive agents
lung disease
cardiovascular disease
Temple University Hospital
 (4.5 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +61 other locations
COVID-19 Convalescent Plasma for Mechanically Ventilated Population

The purpose of this study is to see if this plasma can be safely used in humans with COVID-19 and to see if it can improve patients' health when they are sick with COVID-19.

ct scan
mechanical ventilation
pneumonia
covid-19
SARS
Hospital of the University of Pennsylvania
 (4.2 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location
Influence of Cooling Duration on Efficacy in Cardiac Arrest Patients

A multicenter, randomized, adaptive allocation clinical trial to determine if increasing durations of induced hypothermia are associated with an increasing rate of good neurological outcomes and to identify the optimal duration of induced hypothermia for neuroprotection in comatose survivors of cardiac arrest.

resuscitation
cardiac arrest
induced hypothermia
hypothermia
life support
Temple University Hospital
 (4.5 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +12 other locations
A Study of Tirzepatide (LY3298176) Compared With Dulaglutide on Major Cardiovascular Events in Participants With Type 2 Diabetes

The purpose of the trial is to assess the efficacy and safety of tirzepatide to dulaglutide in participants with type 2 diabetes and increased cardiovascular risk.

body mass index
tirzepatide
cardiovascular disease
dulaglutide
Thomas Jefferson University
 (5.6 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +650 other locations
Durvalumab With or Without Olaparib as Maintenance Therapy After First-Line Treatment of Advanced and Recurrent Endometrial Cancer

A study to assess the efficacy and safety of durvalumab in combination with platinum-based chemotherapy (paclitaxel + carboplatin) followed by maintenance durvalumab with or without olaparib for patients with newly diagnosed advanced or recurrent endometrial cancer.

immunomodulator
cancer
durvalumab
maintenance therapy
carcinoma
Research Site
 (8.2 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +94 other locations
A Study of Donanemab (LY3002813) in Participants With Early Alzheimer's Disease (TRAILBLAZER-ALZ 2)

The reason for this study is to see how safe and effective the study drug donanemab is in participants with early Alzheimer's disease.

florbetapir
flortaucipir
mini-mental state examination
alzheimer's disease
positron emission tomography
University of Pennsylvania Heath System
 (4.2 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +85 other locations