Lyndhurst, Ohio Clinical Trials

A listing of Lyndhurst, Ohio clinical trials actively recruiting patient volunteers.

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Found 59 clinical trials
A Study to Evaluate the Efficacy and Safety of Intravenous Prasinezumab in Participants With Early Parkinson's Disease  

This is a multicenter, randomized, double-blind, placebo-controlled study that will evaluate the efficacy and safety of intravenous (IV) prasinezumab versus placebo in participants with Early Parkinson's Disease (PD) who are on stable symptomatic PD medication.

resting tremor
bradykinesia
tremor
dopamine transporter
early parkinson's
Cleveland Clinic
 (6.9 away)
  • 0 views
  • 28 Jun, 2022
  • +125 other locations
Implementing Models for Mechanical Circulatory Support Presurgical Assessment in Congenital Heart Disease Treatment (IMMPACT)

The purpose of this research study is to look at the advantages of using a 3D printed heart model for surgical planning in children who have been diagnosed with Congenital Heart Disease (CHD) and clinical heart failure and will undergo a ventricular assist device (VAD) placement. The investigators want to …

Cleveland Clinic
 (6.9 away) Contact site
  • 0 views
  • 05 Jul, 2023
  • +8 other locations
Implementing Models for Mechanical Circulatory Support Presurgical Assessment in Congenital Heart Disease Treatment (IMMPACTTest123)

The purpose of this research study is to look at the advantages of using a 3D printed heart model for surgical planning in children who have been diagnosed with Congenital Heart Disease (CHD) and clinical heart failure and will undergo a ventricular assist device (VAD) placement. The investigators want to …

Cleveland Clinic
 (6.9 away) Contact site
  • 0 views
  • 28 Mar, 2024
  • +8 other locations
FemBloc Permanent Contraception Trial

The purpose of this study is to evaluate if changes to the FemBloc Permanent Contraceptive System are effective in increasing reliance (the ability of a woman to be able to depend on FemBloc for contraception once the treatment and confirmation test have been performed), and decreasing pregnancy rate. In addition, …

University Hospitals - Cleveland Medical Center
 (4.0 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +2 other locations
A Study of LY3819253 (LY-CoV555) in Participants With Mild to Moderate COVID-19 Illness

The purpose of this study is to measure how well LY3819253 works against the virus that causes COVID-19. LY3819253 will be given to participants with early symptoms of COVID-19, via an injection into a vein. Samples will be taken from the back of the nose to determine how much virus …

sickle cell disease
malaise
chronic disease
headache
fever
Cleveland Clinic
 (6.9 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +61 other locations
No Opioids vs. Minimal Opioids Following Inguinal Hernia Repair

The investigators hypothesize that not prescribing opioids after uncomplicated, outpatient IHR will be non-inferior to prescribing opioids (5 tablets of Oxycodone, 5mg; or surgeon preference for intolerance) with respect to requests for opioid refills. Additionally, the investigators believe there will be no significant difference in postoperative readmission for pain quality …

Cleveland Clinic Center for Abdominal Core Health
 (6.9 away) Contact site
  • 0 views
  • 06 Jul, 2023
  • 1 location
A Study to Test a Medicine (Fitusiran) Injected Under the Skin for Preventing Bleeding Episodes in Male Adolescent or Adult Participants With Severe Hemophilia (ATLAS-NEO)

This is a multicenter, multinational, open-label, one-way cross-over, Phase 3, single-arm study for treatment of hemophilia. The purpose of this study is to measure the frequency of treated bleeding episodes with fitusiran in male adult and adolescent (≥12 years old) participants with hemophilia A or B, with or without inhibitory …

University Hospitals of Cleveland Site Number : 8400001
 (6.2 away) Contact site
  • 0 views
  • 24 May, 2024
  • +53 other locations
A Study of Tirzepatide (LY3298176) Compared With Dulaglutide on Major Cardiovascular Events in Participants With Type 2 Diabetes

The purpose of the trial is to assess the efficacy and safety of tirzepatide to dulaglutide in participants with type 2 diabetes and increased cardiovascular risk.

body mass index
cardiovascular disease
dulaglutide
tirzepatide
Cleveland Clinic
 (6.9 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +650 other locations
A Study of Donanemab (LY3002813) in Participants With Early Alzheimer's Disease (TRAILBLAZER-ALZ 2)

The reason for this study is to see how safe and effective the study drug donanemab is in participants with early Alzheimer's disease.

florbetapir
mini-mental state examination
alzheimer's disease
flortaucipir
positron emission tomography
Rapid Medical Research Inc
 (3.1 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +85 other locations
A Phase 3 Study to Evaluate Efficacy and Safety of AL001 in Frontotemporal Dementia (INFRONT-3)

A phase 3 double blind, placebo controlled study evaluating the efficacy and safety of AL001 in participants at risk for or with frontotemporal dementia due to heterozygous mutations in the progranulin gene.

progranulin
aphasia
dementia
pick's disease
Case Western Reserve University
 (6.2 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +46 other locations