Lakewood, Ohio Clinical Trials

A listing of Lakewood, Ohio clinical trials actively recruiting patient volunteers.

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Found 47 clinical trials
Implementing Models for Mechanical Circulatory Support Presurgical Assessment in Congenital Heart Disease Treatment (IMMPACT)

The purpose of this research study is to look at the advantages of using a 3D printed heart model for surgical planning in children who have been diagnosed with Congenital Heart Disease (CHD) and clinical heart failure and will undergo a ventricular assist device (VAD) placement. The investigators want to …

Cleveland Clinic
 (9.4 away) Contact site
  • 0 views
  • 05 Jul, 2023
  • +8 other locations
Implementing Models for Mechanical Circulatory Support Presurgical Assessment in Congenital Heart Disease Treatment (IMMPACTTest123)

The purpose of this research study is to look at the advantages of using a 3D printed heart model for surgical planning in children who have been diagnosed with Congenital Heart Disease (CHD) and clinical heart failure and will undergo a ventricular assist device (VAD) placement. The investigators want to …

Cleveland Clinic
 (9.4 away) Contact site
  • 0 views
  • 28 Mar, 2024
  • +8 other locations
A Study of LY3819253 (LY-CoV555) in Participants With Mild to Moderate COVID-19 Illness

The purpose of this study is to measure how well LY3819253 works against the virus that causes COVID-19. LY3819253 will be given to participants with early symptoms of COVID-19, via an injection into a vein. Samples will be taken from the back of the nose to determine how much virus …

sore throat
chronic obstructive pulmonary disease
immunosuppressive agents
lung disease
cardiovascular disease
Cleveland Clinic
 (9.4 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +61 other locations
No Opioids vs. Minimal Opioids Following Inguinal Hernia Repair

The investigators hypothesize that not prescribing opioids after uncomplicated, outpatient IHR will be non-inferior to prescribing opioids (5 tablets of Oxycodone, 5mg; or surgeon preference for intolerance) with respect to requests for opioid refills. Additionally, the investigators believe there will be no significant difference in postoperative readmission for pain quality …

Cleveland Clinic Center for Abdominal Core Health
 (9.4 away) Contact site
  • 0 views
  • 06 Jul, 2023
  • 1 location
A Study of Tirzepatide (LY3298176) Compared With Dulaglutide on Major Cardiovascular Events in Participants With Type 2 Diabetes

The purpose of the trial is to assess the efficacy and safety of tirzepatide to dulaglutide in participants with type 2 diabetes and increased cardiovascular risk.

body mass index
tirzepatide
cardiovascular disease
dulaglutide
Cleveland Clinic
 (9.4 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +650 other locations
Durvalumab With or Without Olaparib as Maintenance Therapy After First-Line Treatment of Advanced and Recurrent Endometrial Cancer

A study to assess the efficacy and safety of durvalumab in combination with platinum-based chemotherapy (paclitaxel + carboplatin) followed by maintenance durvalumab with or without olaparib for patients with newly diagnosed advanced or recurrent endometrial cancer.

immunomodulator
cancer
durvalumab
maintenance therapy
carcinoma
Research Site
 (5.6 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +94 other locations
Single- vs. Two-Fraction Spine Stereotactic Radiosurgery for the Treatment of Vertebral Metastases

Spine radiosurgery (SRS) utilizes advanced treatment planning with focused x-rays to deliver one to four high dose treatments to the spine to help relieve pain and/or neurologic symptoms. Spine SRS uses special equipment to position the participant and guide the focused beams toward the area to be treated and away …

bone scan
neurologic symptoms
spinal cord
mri spine
metastasis
Cleveland Clinic Taussig Cancer Center
 (9.4 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location
ATR Inhibitor BAY 1895344 Plus Niraparib Phase 1b Study in Advanced Solid Tumors and Ovarian Cancer

The purpose of the study is to test how well patients with advanced solid tumors and ovarian cancer respond to treatment with BAY1895344 in combination with niraparib. In addition researchers want to find for patients the optimal dose of BAY1895344 in combination with niraparib, how the drug is tolerated and …

serum pregnancy test
cancer
peritoneal cancer
primary peritoneal carcinoma
muga scan
Cleveland Clinic
 (9.4 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +3 other locations
Tipifarnib for the Treatment of Advanced Solid Tumors Lymphoma or Histiocytic Disorders With HRAS Gene Alterations a Pediatric MATCH Treatment Trial

This phase II pediatric MATCH trial studies how well tipifarnib works in treating patients with solid tumors that have spread to other places in the body (advanced), lymphoma, or histiocytic disorders that have HRAS genetic alterations. Tipifarnib may block the growth of cancer cells that have specific genetic changes in …

pleural effusion
refractory non-hodgkin lymphoma
MRI
growth factor
platelet transfusion
Cleveland Clinic Foundation
 (9.4 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +82 other locations
Adenosine Receptor Antagonist Combination Therapy for Metastatic Castrate Resistant Prostate Cancer

This is a Phase 1b/2, open-label, multicenter platform trial to evaluate the antitumor activity and safety of AB928-based combination therapy in participants with metastatic castrate resistant prostate cancer (mCRPC).

prostatic neoplasms, castration-resistant
castration-resistant prostate cancer
measurable disease
cancer
taxane
Cleveland Clinic
 (9.4 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +21 other locations