Beachwood, Ohio Clinical Trials

A listing of Beachwood, Ohio clinical trials actively recruiting patient volunteers.

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Found 60 clinical trials
A Phase 3 Study to Evaluate Efficacy and Safety of AL001 in Frontotemporal Dementia (INFRONT-3)

A phase 3 double blind, placebo controlled study evaluating the efficacy and safety of AL001 in participants at risk for or with frontotemporal dementia due to heterozygous mutations in the progranulin gene.

pick's disease
aphasia
progranulin
dementia
Case Western Reserve University
 (5.2 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +46 other locations
Fitusiran Prophylaxis in Male Pediatric Subjects Aged 1 to Less Than 12 Years With Hemophilia A or B

Primary Objective: To confirm appropriate dose levels of fitusiran when administered to male pediatric participants (ages 1 to <12 years of age) with severe hemophilia A or B Secondary Objective: To characterize the safety and tolerability To characterize the pharmacokinetics (PK)

fitusiran
factor ix
hemophilia
bethesda assay
haemophilia a
Investigational Site Number 8400007
 (5.2 away) Contact site
  • 0 views
  • 04 Dec, 2020
  • +10 other locations
Fitusiran Prophylaxis in Male Pediatric Subjects Aged 1 to Less Than 12 Years With Hemophilia A or B

Primary Objective: To confirm appropriate dose levels of fitusiran when administered to male pediatric participants (ages 1 to <12 years of age) with severe hemophilia A or B Secondary Objective: To characterize the safety and tolerability To characterize the pharmacokinetics (PK)

fitusiran
factor ix
hemophilia
bethesda assay
haemophilia a
Investigational Site Number 8400007
 (5.2 away) Contact site
  • 0 views
  • 04 Dec, 2020
  • +5 other locations
Single- vs. Two-Fraction Spine Stereotactic Radiosurgery for the Treatment of Vertebral Metastases

Spine radiosurgery (SRS) utilizes advanced treatment planning with focused x-rays to deliver one to four high dose treatments to the spine to help relieve pain and/or neurologic symptoms. Spine SRS uses special equipment to position the participant and guide the focused beams toward the area to be treated and away …

compression fracture
neurologic symptoms
mri spine
stereotactic radiosurgery
metastasis
Cleveland Clinic Taussig Cancer Center
 (5.5 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location
Ketorolac as an Adjuvant Agent for Postoperative Pain Control Following Arthroscopic Meniscus Surgery

The utilization of arthroscopic surgery to treat meniscus injuries has continued to increase in recent years, partly due to a younger, more active population, and improved technology and technique. However, pain management in the post-operative period is critical to the ability to perform this procedure as an outpatient surgery. Traditionally, …

drugs of abuse
ketorolac
NSAID
drug abuse
nausea
UH Cleveland Medical Center
 (5.2 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location
ATR Inhibitor BAY 1895344 Plus Niraparib Phase 1b Study in Advanced Solid Tumors and Ovarian Cancer

The purpose of the study is to test how well patients with advanced solid tumors and ovarian cancer respond to treatment with BAY1895344 in combination with niraparib. In addition researchers want to find for patients the optimal dose of BAY1895344 in combination with niraparib, how the drug is tolerated and …

solid tumour
metastasis
tumor cells
ovarian cancer
malnutrition
Cleveland Clinic
 (5.5 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +3 other locations
A Safety Study of Oral Venetoclax in Combination With Intravenous Pembrolizumab in Adult Participants With Previously Untreated Non-Small Cell Lung Cancer (NSCLC) With High Programmed Cell Death Ligand-1 (PD-L1) Expression

Non-Small Cell Lung Cancer (NSCLC) is a solid tumor, a disease in which cancer cells form in the tissues of the lung. It is the most common form of lung cancer, accounting for around 85% of lung cancers. The purpose of this study is to evaluate the safety and efficacy …

anaplastic lymphoma
pd-l1
lung cancer
lymphoma
stage iv non-small cell lung cancer
University Hospitals Cleveland /ID# 212241
 (5.2 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +38 other locations
Tipifarnib for the Treatment of Advanced Solid Tumors Lymphoma or Histiocytic Disorders With HRAS Gene Alterations a Pediatric MATCH Treatment Trial

This phase II pediatric MATCH trial studies how well tipifarnib works in treating patients with solid tumors that have spread to other places in the body (advanced), lymphoma, or histiocytic disorders that have HRAS genetic alterations. Tipifarnib may block the growth of cancer cells that have specific genetic changes in …

cancer therapy
rhabdomyosarcoma recurrent
recurrent thyroid gland carcinoma
pediatric
glomerular filtration rate
Cleveland Clinic Foundation
 (5.5 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +82 other locations
Optimization of NIBS for Treatment of Addiction

The purpose of this study is to assess the effects of transcranial Direct Current Stimulation (tDCS) applied in conjunction with Transcranial Ultrasound (TUS) for the treatment of addiction in opiate use disorder with chronic pain. The investigators hypothesize that there will be a decrease in drug use and improved psychosocial …

narcotic use
opioid
drug use
opiates
psychiatric disorder
University Hospitals Cleveland Medical Center/ Dahms Clinical Research Unit
 (5.2 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location
Reducing Stroke Risk in African-American Men

The project is a 6-month prospective Randomized Controlled Trial evaluating the effects of TargEted MAnageMent Intervention (TEAM, N=80) vs. wait-list (WL, N=80) control in African American men who have experienced a stroke or TIA within the past 5 years.

stroke
acute stroke
Case Western Reserve University
 (5.2 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location