Haddon Heights, New Jersey Clinical Trials

A listing of Haddon Heights, New Jersey clinical trials actively recruiting patient volunteers.

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Found 102 clinical trials
Study to Evaluate the Effect of GBT440 on TCD in Pediatrics With Sickle Cell Disease

This study is a Phase 3, randomized, double-blind, placebo-controlled study of voxelotor in pediatric participants, aged 2 to < 15 years old, with Sickle Cell Disease. The primary objective is to evaluate the effect of voxelotor on the TCD (Transcranial Doppler Ultrasound) measurements in SCD participants in this age range.

gbt440
cerebral blood flow
pediatric
voxelotor
transcranial doppler ultrasonography
Children's Hospital of Philadelphia
 (8.7 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +34 other locations
A Study to Evaluate the Efficacy and Safety of JCAR017 in Adult Subjects With Relapsed or Refractory Indolent B-cell Non-Hodgkin Lymphoma (NHL)

This is a global Phase 2, open-label, single-arm, multicohort, multicenter study to evaluate efficacy and safety of JCAR017 in adult subjects with r/r FL or MZL. The study will be conducted in compliance with the International Council on Harmonisation (ICH) of Technical Requirements for Registration of Pharmaceuticals for Human Use/Good …

alkylating agents
marginal zone lymphoma
refractory follicular lymphoma
non-hodgkin lymphoma
leukapheresis
Perelman Center for Advanced Medicine - Abramson Cancer Center University of Pennsylvania
 (8.7 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +35 other locations
Project MiNT: Assessing the Impact of Food & Video-Based Nutrition Education on Patients With Poorly Controlled Diabetes

This pragmatic randomized controlled trial will assess the efficacy of medically tailored meals and medical nutrition therapy via telehealth on clinical outcomes for patients with poorly controlled type 2 diabetes. The goal of these interventions is to improve outcomes for patients with diabetes by impacting self-care behaviors and diet self-efficacy …

nutritional support
medical nutrition therapy
nutrition education
Thomas Jefferson University Hospital
 (7.2 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location
Outcome Study Assessing a 75 Milligrams (mg) Dose of Macitentan in Patients With Pulmonary Arterial Hypertension

The purpose of this study is to demonstrate superiority of macitentan 75 milligrams (mg) in prolonging the time to the first clinical events committee (CEC)-adjudicated morbidity or mortality (M/M) event in participants with symptomatic pulmonary arterial hypertension (PAH) compared to macitentan 10 mg.

HIV Infection
ventricular septal defect
hypertension
hemodynamic evaluation
septal defect
University of Pennsylvania
 (8.7 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +210 other locations
A Study Evaluating The Safety Tolerability Pharmacokinetics And Efficacy Of Venetoclax In Combination With Atezolizumab Carboplatin And Etoposide In Participants With Untreated Extensive-Stage Small Cell Lung Cancer (ES-SCLC).

A study consisting of a dose-escalation phase and a dose-expansion phase to evaluate the safety, tolerability, pharmacokinetics, and efficacy of venetoclax in combination with atezolizumab, carboplatin, and etoposide.

granulocyte colony stimulating factor
cancer treatment
small cell lung cancer
colony stimulating factor
cancer therapy
University of Pennsylvania
 (8.7 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +15 other locations
A Medical Research Study Designed to Determine if Venglustat Can be a Future Treatment for ADPKD Patients

Primary Objective: To determine the effect of venglustat on the rate of total kidney volume (TKV) growth (Stage and estimated glomerular filtration rate (eGFR) decline in patients at risk of rapidly progressive Autosomal Dominant Polycystic Kidney Disease (ADPKD) (Stage 2). Secondary Objectives: To determine the effect of venglustat on the …

fatigue
depression
cyst
urine osmolality
chronic kidney disease
Investigational Site Number 8400011
 (8.7 away) Contact site
  • 0 views
  • 04 Dec, 2020
  • +80 other locations
Phase 2 Study of SAR439859 Versus Physician's Choice in Locally Advanced or Metastatic ER-positive Breast Cancer (AMEERA-3)

Primary Objective: To determine whether SAR439859 per os improves progression free survival (PFS) when compared with a endocrine monotherapy of the choice of the physician, in participants with metastatic or locally advanced breast cancer. Secondary Objectives: To compare the overall survival in the 2 treatment arms To assess the objective …

oestrogen receptor positive breast cancer
tamoxifen
immunological adjuvant
endocrine therapy
stage iv breast cancer
Investigational Site Number 8400001
 (9.5 away) Contact site
  • 0 views
  • 04 Dec, 2020
  • +125 other locations
A Study to Evaluate the Efficacy and Safety of Intravenous Prasinezumab in Participants With Early Parkinson's Disease  

This is a multicenter, randomized, double-blind, placebo-controlled study that will evaluate the efficacy and safety of intravenous (IV) prasinezumab versus placebo in participants with Early Parkinson's Disease (PD) who are on stable symptomatic PD medication.

resting tremor
dopamine transporter
parkinsonism
early parkinson's
tremor
University Pennsylvania Hospital
 (8.7 away)
  • 0 views
  • 28 Jun, 2022
  • +125 other locations
A Study Evaluating the Efficacy and Safety of Adjuvant Atezolizumab or Placebo and Trastuzumab Emtansine for Participants With HER2-Positive Breast Cancer at High Risk of Recurrence Following Preoperative Therapy

This is a Phase III, two-arm, randomized, double-blind placebo-controlled study in participants with HER2-positive primary breast cancer who have received preoperative chemotherapy and HER2-directed therapy, including trastuzumab followed by surgery, with a finding of residual invasive disease in the breast and/or axillary lymph nodes.

MD Anderson Cancer Center at Cooper
 (4.8 away) Contact site
  • 0 views
  • 05 Oct, 2021
  • +301 other locations
A Study of Tucatinib vs. Placebo in Combination With Ado-trastuzumab Emtansine (T-DM1) for Patients With Advanced or Metastatic HER2+ Breast Cancer

This study is being done to see if tucatinib with ado-trastuzumab emtansine (T-DM1) works better than T-DM1 alone to help patients who have a specific type of breast cancer called HER2 positive breast carcinoma. The breast cancer in this study is either metastatic (spread into other parts of the body) …

University of Pennsylvania / Perelman Center for Advanced Medicine
 (8.7 away) Contact site
  • 0 views
  • 14 Mar, 2022
  • +227 other locations