Hackensack, New Jersey Clinical Trials

A listing of Hackensack, New Jersey clinical trials actively recruiting patient volunteers.

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Found 193 clinical trials
A Study to Test a Medicine (Fitusiran) Injected Under the Skin for Preventing Bleeding Episodes in Male Adolescent or Adult Participants With Severe Hemophilia (ATLAS-NEO)

This is a multicenter, multinational, open-label, one-way cross-over, Phase 3, single-arm study for treatment of hemophilia. The purpose of this study is to measure the frequency of treated bleeding episodes with fitusiran in male adult and adolescent (≥12 years old) participants with hemophilia A or B, with or without inhibitory …

Hackensack University Site Number : 8400009
 (0.1 away) Contact site
  • 0 views
  • 24 May, 2024
  • +53 other locations
Systematic Evaluation of Ablation Techniques for Non-Paroxysmal Atrial Fibrillation.

The purpose of this study is to evaluate the safety and effectiveness of empirical posterior wall isolation (PWI), left atrial appendage electrical isolation (LAAEI) and coronary sinus isolation (CSI) when compared to pulmonary vein isolation (PVI) alone: PVI alone, PVI + PWI, PVI + PWI + LAAEI, PVI + PWI …

left ventricular dysfunction
atrial fibrillation
paroxysmal atrial fibrillation
chest pain
dyspnea
Montefiore Medical Center
 (9.4 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +3 other locations
Influence of Cooling Duration on Efficacy in Cardiac Arrest Patients

A multicenter, randomized, adaptive allocation clinical trial to determine if increasing durations of induced hypothermia are associated with an increasing rate of good neurological outcomes and to identify the optimal duration of induced hypothermia for neuroprotection in comatose survivors of cardiac arrest.

cardiac arrest
hypothermia
life support
coma
resuscitation
NYP Columbia University Medical Center
 (6.4 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +12 other locations
Manhattan Vision Screening and Follow-Up Study

The investigators are conducting a 5-year prospective, cluster-randomized controlled trial, funded by the Centers for Disease Control (CDC), which provides vision screenings to underserved, vulnerable New York City residents living in affordable housing buildings in Harlem and Washington Heights.

vision screening
Columbia University
 (6.4 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location
Durvalumab With or Without Olaparib as Maintenance Therapy After First-Line Treatment of Advanced and Recurrent Endometrial Cancer

A study to assess the efficacy and safety of durvalumab in combination with platinum-based chemotherapy (paclitaxel + carboplatin) followed by maintenance durvalumab with or without olaparib for patients with newly diagnosed advanced or recurrent endometrial cancer.

sarcoma
paclitaxel
cancer treatment
recurrent endometrial cancer
measurable disease
Research Site
 (2.0 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +94 other locations
Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer ALCHEMIST Chemo-IO Study

This phase III ALCHEMIST trial compares the addition of pembrolizumab to usual chemotherapy versus usual chemotherapy for the treatment of stage IB, II, or IIIA non-small cell lung cancer that has been removed by surgery. Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the …

sarcoma
lung non-small cell squamous carcinoma
cisplatin/gemcitabine
small cell lung cancer
pemetrexed
Neurosurgeons of New Jersey-Ridgewood
 (7.2 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +358 other locations
A Phase 3 Study to Evaluate Efficacy and Safety of AL001 in Frontotemporal Dementia (INFRONT-3)

A phase 3 double blind, placebo controlled study evaluating the efficacy and safety of AL001 in participants at risk for or with frontotemporal dementia due to heterozygous mutations in the progranulin gene.

dementia
pick's disease
progranulin
aphasia
Irving Institute for Clinical and Translational Research
 (6.4 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +46 other locations
NA-831 Atazanavir and Dexamethasone Combination Therapy for the Treatment of COVID-19 Infection

This Phase 2/3 trial evaluates four treatment strategies for non-critically ill hospitalized participants (not requiring ICU admission and/or mechanical ventilation) with SARS CoV-2 infection, in which participants will receive NA-831 or Atazanavir with or without Dexamethasone.

covid-19
combination therapy
acute respiratory syndrome (sars)
complete blood count
cervical cap
Coronavirus Research Institute-Testing Site-
 (9.4 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +29 other locations
A Study of Lasmiditan (LY573144) Treatment in Children Aged 6 to 17 With Migraine

The reason for this study is to see if lasmiditan is safe and effective in children aged 6 to 17 with migraine. The study will last up to 20 weeks and may include up to 4 visits.

migraine
treatment regimen
preventive medication
ly573144
lasmiditan
Columbia University
 (6.4 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +162 other locations
Fitusiran Prophylaxis in Male Pediatric Subjects Aged 1 to Less Than 12 Years With Hemophilia A or B

Primary Objective: To confirm appropriate dose levels of fitusiran when administered to male pediatric participants (ages 1 to <12 years of age) with severe hemophilia A or B Secondary Objective: To characterize the safety and tolerability To characterize the pharmacokinetics (PK)

factor ix
severe haemophilia a
antihemophilic factor
hemophilia
fitusiran
Investigational Site Number 8400008
 (0.1 away) Contact site
  • 0 views
  • 04 Dec, 2020
  • +10 other locations