Englewood, New Jersey Clinical Trials

A listing of Englewood, New Jersey clinical trials actively recruiting patient volunteers.

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Found 201 clinical trials
Study of CB-5339 in Acute Myeloid Leukemia or Myelodysplastic Syndrome

This is a multicenter, open-label Phase 1 study of orally administered CB-5339 in participants with R/R AML or participants with R/R intermediate- to high-risk MDS.

myeloid leukemia
remission
gilbert's syndrome
acute myeloid leukemia
refractory acute myeloid leukemia (aml)
Memorial Sloan Kettering Cancer Center
 (8.6 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +4 other locations
Assessing Minimal Residual Disease by Next- Generation Sequencing to Minimize Exposure in People With CLL or SLL Who Have Been Treated With Venetoclax

This study will find out whether people with CLL or SLL who have received treatment with venetoclax, either alone or in combination with another drug, and who are found to be MRD-negative, can stop treatment with venetoclax and remain off-treatment for 12 months or more. The researchers will also see …

formalin-fixed paraffin-embedded
remission
bone marrow biopsy
monoclonal antibodies
minimal residual disease
Memorial Sloan Kettering Cancer Center (All Protocol Activities)
 (9.0 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +9 other locations
THE ALIGN-AR PIVOTAL TRIAL: JenaValve Pericardial TAVR Aortic Regurgitation Study

To collect information about treatment for symptomatic severe Aortic Regurgitation (AR), which affects the aortic valve in the heart. Aortic regurgitation is a condition where aortic valve in the heart does not close tightly and allows some blood to leak back into the heart chamber. Symptoms of aortic regurgitation may …

aortic valve replacement
fatigue
shortness of breath
regurgitation
New York-Presbyterian/ Columbia University Medical Center
 (4.0 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +9 other locations
A Study of Hydroxychloroquine vs Placebo to Prevent COVID-19 Infection in Patients Receiving Radiotherapy

The researchers are doing this study to find out whether the study drug hydroxychloroquine can prevent infection with the COVID-19 virus, compared with placebo, in people who are receiving radiation therapy for their cancer. The placebo used in this study is a tablet that looks the same as the study …

sore throat
SARS
anosmia
antigen test
covid-19
Memorial Sloan Kettering Cancer Center (All Protocol Activities)
 (9.0 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +6 other locations
First-in-human Single Agent Study of SAR442085 in Relapsed or Refractory Multiple Myeloma

Primary Objectives: Dose Escalation Part A: To determine the maximum tolerated dose (MTD) of SAR442085 administered as a single agent in patients with relapsed or refractory multiple myeloma (RRMM), and determine the recommended Phase 2 dose (RP2D) for the subsequent Expansion Part B Dose Expansion Part B: To assess the …

monoclonal antibodies
cell transplantation
daratumumab
bortezomib
refractory multiple myeloma
Investigational Site Number 8400001
 (7.3 away) Contact site
  • 0 views
  • 04 Dec, 2020
  • +7 other locations
Treatment With Romosozumab Versus Denosumab to Improve Bone Mineral Density and Architecture in Subacute SCI  

The objective of the proposed work is to determine whether administration for 12 months of romosozumab followed by 12 months of denosumab will maintain bone mass at the knee in subjects with subacute SCI compared to 24 months of denosumab administration alone.

James J. Peters VA Medical Center
 (4.5 away)
  • 0 views
  • 14 Mar, 2022
  • +1 other locations
Treatment With Romosozumab Versus Denosumab to Improve Bone Mineral Density and Architecture in Subacute SCI test  

The objective of the proposed work is to determine whether administration for 12 months of romosozumab followed by 12 months of denosumab will maintain bone mass at the knee in subjects with subacute SCI compared to 24 months of denosumab administration alone.

Accepts healthy volunteers
James J. Peters VA Medical Center
 (4.5 away)
  • 0 views
  • 14 Mar, 2022
  • +1 other locations
PPMI 2.0 Clinical -Establishing a Deeply Phenotyped PD Cohort

The Parkinson Progression Marker Initiative 2.0 (PPMI 2.0) is a longitudinal, observational, multi-center natural history study to assess progression of clinical features, digital outcomes, and imaging, biologic and genetic markers of Parkinson's disease (PD) progression in study participants with manifest PD, prodromal PD, and healthy controls The overall goal of …

muscle rigidity
alpha-synuclein
modafinil
resting tremor
bradykinesia
Columbia University Medical Center
 (4.0 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +45 other locations
International Collaborative Gaucher Group (ICGG) Gaucher Disease Registry & Pregnancy Sub-registry

The ICGG Gaucher Registry is an ongoing, international multi-center, strictly observational program that tracks the routine clinical outcomes for patients with Gaucher disease, irrespective of treatment status. No experimental intervention is involved; patients in the Registry undergo clinical assessments and receive care as determined by the patient's treating physician. The …

imiglucerase
gaucher disease
eliglustat
deficiency
Investigational Site Number 840101
 (3.7 away) Contact site
  • 0 views
  • 04 Dec, 2020
  • +208 other locations
Mucopolysaccharidosis I (MPS I) Registry

The Mucopolysaccharidosis I (MPS I) Registry is an ongoing, observational database that tracks the outcomes of patients with MPS I. The data collected by the MPS I Registry will provide information to better characterize the natural history and progression of MPS I as well as the clinical responses of patients …

Investigational Site Number 840101
 (3.7 away) Contact site
  • 0 views
  • 04 Dec, 2020
  • +124 other locations