Durham, North Carolina Clinical Trials

A listing of Durham, North Carolina clinical trials actively recruiting patient volunteers.

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Found 49 clinical trials
Moisturizer Containing Licochalcone A, Decanediol, L-carnitine and Salicylic Acid in Reducing Relapsing of Acne

Moisturizer containing the active ingredients of licochalcone A, decanediol, L-carnitine, and salicylic acid may be beneficial in alternative treatment of acne in maintenance phase. This study aims to evaluate the efficacy and safety of moisturizer containing the active ingredients of licochalcone A, decanediol, L-carnitine, and salicylic acid during the maintenance …

Online studies
Department of Dermatology, Faculty of Medicine Siriraj Hospital, Mahidol University
(online study) Contact site
  • 0 views
  • 14 Nov, 2025
  • 1 location
  • Online study
RJ_Study_Virtual1  

Acne

Virtual trials
  • 0 views
  • 14 Mar, 2022
  • Online study
Second Primary Lung Cancer Cohort Study (SPORT) (SPORT)  

Patients who have had curative treatment for lung cancer are at an increased risk of developing second primary lung cancers (and other cancers) over the next 10 years. Doctors need to develop better ways of monitoring patients during follow up so we can intervene as quickly as possible with further …

Online studies
Royal Papworth Hospital
(online study)
  • 0 views
  • 12 Feb, 2026
  • 1 location
  • Online study
Prevalence of Subacromial Impingement Among Egyptian Swimmers : A Cross Sectional Survey Study.

In the available literature, there are no prevalence studies that show the incidence of subacromial impingement in swimmers in Egypt, this should be considered as it's one of the most commonly reported injuries worldwide in swimmers. There are also no available studies to show the difference in incidence of subacromial …

Online studies
Nutrilife clinic
(online study) Contact site
  • 0 views
  • 22 Sep, 2022
  • 1 location
  • Online study
Prevalence of Subacromial Impingement Among Egyptian Swimmers : A Cross Sectional Survey Study.

In the available literature, there are no prevalence studies that show the incidence of subacromial impingement in swimmers in Egypt, this should be considered as it's one of the most commonly reported injuries worldwide in swimmers. There are also no available studies to show the difference in incidence of subacromial …

Online studies
Nutrilife clinic
(online study) Contact site
  • 0 views
  • 22 Sep, 2022
  • 1 location
  • Online study
A Study of CAD106 and CNP520 Versus Placebo in Participants at Risk for the Onset of Clinical Symptoms of Alzheimer's Disease

The purpose of this study is to test whether two investigational drugs called CAD106 and CNP520, administered separately, can slow down the onset and progression of clinical symptoms associated with Alzheimer's disease (AD) in participants at the risk to develop clinical symptoms based on their age and genotype.

apolipoprotein e4
alzheimer's disease
mental state examination
mini-mental state examination
Duke University Medical center
 (5.3 away) Contact site
  • 32 views
  • 16 Feb, 2024
  • +126 other locations
Outcome Study Assessing a 75 Milligrams (mg) Dose of Macitentan in Patients With Pulmonary Arterial Hypertension

The purpose of this study is to demonstrate superiority of macitentan 75 milligrams (mg) in prolonging the time to the first clinical events committee (CEC)-adjudicated morbidity or mortality (M/M) event in participants with symptomatic pulmonary arterial hypertension (PAH) compared to macitentan 10 mg.

heart disease
ventricular septal defect
macitentan
macitentan 10 mg
ventricular septal defects
Duke
 (2.4 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +210 other locations
A Study Evaluating The Safety Tolerability Pharmacokinetics And Efficacy Of Venetoclax In Combination With Atezolizumab Carboplatin And Etoposide In Participants With Untreated Extensive-Stage Small Cell Lung Cancer (ES-SCLC).

A study consisting of a dose-escalation phase and a dose-expansion phase to evaluate the safety, tolerability, pharmacokinetics, and efficacy of venetoclax in combination with atezolizumab, carboplatin, and etoposide.

etoposide
cancer treatment
lung cancer
metastasis
measurable disease
Duke Cancer Institute
 (2.4 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +15 other locations
Capivasertib+Abiraterone as Treatment for Patients With Metastatic Hormone-sensitive Prostate Cancer and PTEN Deficiency

This study will assess the efficacy and safety of capivasertib plus abiraterone (+prednisone/prednisolone) plus androgen deprivation therapy (ADT) versus placebo plus abiraterone (+prednisone/prednisolone) plus ADT in participants with mHSPC whose tumours are characterised by PTEN deficiency. The intention of the study is to demonstrate that in participants with mHSPC, the …

antiandrogen therapy
metastasis
prostate cancer
soft tissue lesion
adenocarcinoma of prostate
Research Site
 (2.4 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +106 other locations
A Study to Determine Safety and Efficacy of (REMD-477) in Controlling Hyperglycemia Due to Copanlisib

REMD-477 is a human anti-glucagon receptor antibody. Its proposed mechanism of action in controlling hyperglycemia is by blocking glucagon receptor (GCGR) signaling. In this way, it increases hepatic glucose uptake, decreases hepatic glycogenolysis and gluconeogenesis, increases glycogen synthesis, and ultimately decreases blood glucose levels. This protocol will test the hypotheses …

Duke University Medical Center
 (2.4 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location