Rochester, Minnesota Clinical Trials

A listing of Rochester, Minnesota clinical trials actively recruiting patient volunteers.

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Found 46 clinical trials
Implementing Models for Mechanical Circulatory Support Presurgical Assessment in Congenital Heart Disease Treatment (IMMPACTTest123)

The purpose of this research study is to look at the advantages of using a 3D printed heart model for surgical planning in children who have been diagnosed with Congenital Heart Disease (CHD) and clinical heart failure and will undergo a ventricular assist device (VAD) placement. The investigators want to …

Mayo Clinic
 (1.8 away) Contact site
  • 0 views
  • 28 Mar, 2024
  • +8 other locations
Effect of 1 25-dihydroxyvitamin D3 Treatment on Insulin Secretion and Muscle Strength in Pre-diabetic Persons

The aim of this study is to assess the effects of 1,25(OH)2D3 on insulin secretion by the pancreas and glucose utilization by skeletal muscle as well as to determine the effects of 1,25(OH)2D3 on muscle strength in pre-diabetic persons

prediabetic state
body mass index
fasting
serum glucose
insulin
Mayo Clinic
 (1.8 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location
Glasses for Adolescent Delayed Sleep-Wake Phase Disorder

The purpose of this study is to determine if evening amber glasses combined with stable wake times will show an increase in total sleep time (TST) and an advance in sleep onset times (shift earlier) compared to the control group.

Mayo Clinic in Rochester
 (1.8 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location
Safety and Preliminary Efficacy of JBH492 Monotherapy in Patients With Chronic Lymphocytic Leukemia (CLL) and Non-Hodgkin's Lymphoma (NHL)

The purpose of the First-In-Human study is to assess safety, tolerability, pharmacokinetics (PK), immunogenicity and preliminary efficacy of JBH492 as single agent.

leukemia
lymphoma
chronic lymphocytic leukemia
HIV Infection
hodgkin's disease
Mayo Clinic Rochester
 (1.8 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +5 other locations
A Phase 3 Study to Evaluate Efficacy and Safety of AL001 in Frontotemporal Dementia (INFRONT-3)

A phase 3 double blind, placebo controlled study evaluating the efficacy and safety of AL001 in participants at risk for or with frontotemporal dementia due to heterozygous mutations in the progranulin gene.

progranulin
dementia
aphasia
pick's disease
Mayo Comprehensive Cancer Center - PPDS
 (1.8 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +46 other locations
Phase 2 Trial of Voyager V1 in Combination With Cemiplimab in Cancer Patients

This is a Phase 2 study designed to determine the preliminary anti-tumor activity and confirm the safety of VV1 in combination with cemiplimab. The study will concurrently enroll patients with four distinct advanced malignancies in 5 separate tumor cohorts. The four cancers type are NSCLC and melanoma that are progressing …

metastasis
antiviral drugs
metastatic melanoma
measurable disease
endometrial cancer
Mayo Clinic
 (1.8 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +8 other locations
First-in-human Single Agent Study of SAR442085 in Relapsed or Refractory Multiple Myeloma

Primary Objectives: Dose Escalation Part A: To determine the maximum tolerated dose (MTD) of SAR442085 administered as a single agent in patients with relapsed or refractory multiple myeloma (RRMM), and determine the recommended Phase 2 dose (RP2D) for the subsequent Expansion Part B Dose Expansion Part B: To assess the …

daratumumab
stem cell transplantation
measurable disease
lenalidomide
thalidomide
Investigational Site Number 8400005
 (1.8 away) Contact site
  • 0 views
  • 04 Dec, 2020
  • +7 other locations
Identification of Predictors for Clinical Outcomes in Femoroacetabular Impingement Surgery

The overarching goal of the study is to improve the surgical treatment outcomes of FAI, which is affecting an increasing number of military personnel and young active individuals in the general population. The proposed study will investigate critical patient, disease, and surgical treatment predictors of FAI surgery outcomes.

femoroacetabular impingement
conservative management
arthroscopy
hip arthroscopy
Mayo Clinic
 (5.5 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +11 other locations
Cohort Study of Pancreatic Cancer Risk

This study is designed to develop a cohort of individuals without pancreatic cancer, but who are at increased risk of developing it due to family history or genetic predisposition. These high-risk individuals will be asked to provide baseline and annual (serial) follow-up blood samples for the duration of the study …

Mayo Clinic
 (5.5 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location
Standardizing Method and Development of Normal Values to Measure Human Small Intestinal and Colonic Permeability

To develop a test to measure small bowel and colonic permeability.

Mayo Clinic
 (1.8 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location