Minneapolis, Michigan Clinical Trials

A listing of Minneapolis, Michigan clinical trials actively recruiting patient volunteers.

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Found 60 clinical trials
Testing the Addition of the Drug Atezolizumab to the Usual Radiation Treatment for Patients With Early Non-small Cell Lung Cancer

This trial studies how well atezolizumab added to the usual radiation therapy works in treating patients with stage I-IIA non-small cell lung cancer. Immunotherapy with monoclonal antibodies, such as atezolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow …

stereotactic body radiation therapy
small cell lung cancer
stage ib lung cancer ajcc v8
lung cancer
neutrophil count
Regions Hospital
 (8.7 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +21 other locations
FT596 as a Monotherapy and in Combination With Anti-CD20 Monoclonal Antibodies

This is a Phase I dose-finding study of FT596 as monotherapy and in combination with Rituximab or Obinutuzumab in subjects with relapsed/refractory B-cell Lymphoma or Chronic Lymphocytic Leukemia. The study will consist of a dose-escalation stage and an expansion stage where participants will be enrolled into indication-specific cohorts.

antibody therapy
chronic lymphocytic leukemia
rituximab fludarabine
monoclonal antibodies
leukemia
University of Minnesota Masonic Cancer Center
 (1.5 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +2 other locations
Testing the Addition of Radiotherapy to the Usual Treatment (Chemotherapy) for Patients With Esophageal and Gastric Cancer That Has Spread to a Limited Number of Other Places in the Body

This phase III trial studies how well the addition of radiotherapy to the usual treatment (chemotherapy) works compared to the usual treatment alone in treating patients with esophageal and gastric cancer that has spread to a limited number of other places in the body (oligometastatic disease). Radiotherapy uses high energy …

definitive treatment
chemoradiotherapy
neutrophil count
oral contraceptives
treatment regimen
Hennepin County Medical Center
 (0.4 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +254 other locations
KEAPSAKE: A Study of Telaglenastat (CB-839) With Standard-of-Care Chemoimmunotherapy in 1L KEAP1/NRF2-Mutated Nonsquamous NSCLC

This is a Phase 2, randomized, multicenter, double-blind study of the glutaminase inhibitor telaglenastat with standard-of-care pembrolizumab and chemotherapy versus placebo with standard-of-care pembrolizumab and chemotherapy for first line treatment of metastatic disease in patients with KEAP1/NRF2-mutated, stage IV, nonsquamous, non-small cell lung cancer (NSCLC). The study primary endpoints are …

STK11
systemic therapy
pemetrexed
measurable disease
adjuvant
Minnesota Oncology Hematology, P.A.
 (1.2 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +27 other locations
Renal Impairment Study of PF-06700841

The purpose of this study is to characterize the effect of kidney impairment on the blood concentrations of PF-06700841 and its major metabolite. Findings from this study will be used to develop dosing recommendations so that the dose and/or dosing interval may be adjusted appropriately in the presence of kidney …

renal impairment
renal function test
kidney function tests
nephropathy
renal function
Prism Clinical Research, LLC
 (3.4 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +2 other locations
The Effect of Inflammation and Damage to Lymph Node Structures on Durable Protective Immunity Following Vaccination

Hypothesis: Infections other than HIV can cause LN inflammation and collagen damage to the fibroblastic reticular cell network (FRCn), which will lead to CD4 T cell depletion and impaired vaccine responses. This protocol will study yellow fever vaccine (YFV) in two cohorts of people, one from Uganda and the other …

vaccination
yellow fever
immunosuppressive
University of Minnesota
 (1.5 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +1 other locations
A Study to Evaluate the Safety and Tolerability of Venetoclax Tablets in Combination With Capecitabine Tablets in Adult Participants With Hormone Receptor-Positive HER2-Negative Locally Advanced or Metastatic Breast Cancer Who Had Disease Progression During or After CDK4/6 Inhibitor Therapy

Endocrine therapy is the initial treatment for most hormone receptor positive (HR+), human epidermal growth factor receptor 2 negative (HER2-) breast cancers. This study will evaluate the use of venetoclax in combination with capecitabine in adult participants with HR+, HER2-, metastatic breast cancer (MBC) who had disease progression following treatment …

HER2
hormone therapy
capecitabine
primary tumor
measurable disease
Masonic Cancer Center /ID# 216101
 (1.5 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +15 other locations
A Phase 3 Safety and Efficacy Study of Intravitreal Administration of Zimura (Complement C5 Inhibitor)

The objectives of this study are to evaluate the safety and efficacy of Zimura intravitreal administration in patients with geographic atrophy secondary to age-related macular degeneration (AMD)

complement c5
geographic atrophy
atrophy
maculopathy
macular degeneration
Retina Center
 (1.2 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +22 other locations
Identification of Predictors for Clinical Outcomes in Femoroacetabular Impingement Surgery

The overarching goal of the study is to improve the surgical treatment outcomes of FAI, which is affecting an increasing number of military personnel and young active individuals in the general population. The proposed study will investigate critical patient, disease, and surgical treatment predictors of FAI surgery outcomes.

arthroscopy
femoroacetabular impingement
hip arthroscopy
conservative management
Twin Cities Orthopedics
 (8.0 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +11 other locations
International Collaborative Gaucher Group (ICGG) Gaucher Disease Registry & Pregnancy Sub-registry

The ICGG Gaucher Registry is an ongoing, international multi-center, strictly observational program that tracks the routine clinical outcomes for patients with Gaucher disease, irrespective of treatment status. No experimental intervention is involved; patients in the Registry undergo clinical assessments and receive care as determined by the patient's treating physician. The …

gaucher disease
imiglucerase
eliglustat
deficiency
Investigational Site Number 840046
 (1.2 away) Contact site
  • 0 views
  • 04 Dec, 2020
  • +208 other locations