Ann Arbor, Michigan Clinical Trials

A listing of Ann Arbor, Michigan clinical trials actively recruiting patient volunteers.

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Found 51 clinical trials
Outcome Study Assessing a 75 Milligrams (mg) Dose of Macitentan in Patients With Pulmonary Arterial Hypertension

The purpose of this study is to demonstrate superiority of macitentan 75 milligrams (mg) in prolonging the time to the first clinical events committee (CEC)-adjudicated morbidity or mortality (M/M) event in participants with symptomatic pulmonary arterial hypertension (PAH) compared to macitentan 10 mg.

heart disease
right heart catheterization
connective tissue disease
ventricular septal defects
patent ductus arteriosus
University of Michigan
 (6.1 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +210 other locations
A Study of Tucatinib vs. Placebo in Combination With Ado-trastuzumab Emtansine (T-DM1) for Patients With Advanced or Metastatic HER2+ Breast Cancer

This study is being done to see if tucatinib with ado-trastuzumab emtansine (T-DM1) works better than T-DM1 alone to help patients who have a specific type of breast cancer called HER2 positive breast carcinoma. The breast cancer in this study is either metastatic (spread into other parts of the body) …

University of Michigan Comprehensive Cancer Center
 (6.1 away) Contact site
  • 0 views
  • 14 Mar, 2022
  • +227 other locations
Clinical Trial for Surgery of the Ulnar Nerve (SUN) at the Elbow

This research is studying two surgical procedures in a large group of people to learn about how well these procedures work as a treatment for ulnar neuropathy at the elbow (UNE). Researchers want to see which surgery is more helpful for people with ulnar neuropathy. This research will determine if …

Michigan Medicine
 (6.1 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +9 other locations
A Study of LY3819253 (LY-CoV555) in Participants Hospitalized for COVID-19

The purpose of this study is to test the safety and tolerability of LY3819253 when it is given by injection into a vein to participants hospitalized with COVID-19. Blood tests will be done to check how much LY3819253 is in the bloodstream and how long the body takes to eliminate …

blood test
covid-19
University of Michigan
 (6.1 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +10 other locations
Dose De-escalation Study of the PI3k Alpha/Delta Inhibitor Copanlisib Given in Combination With the Immunotherapeutic Agents Nivolumab and Rituximab in Patients With Relapsed/Refractory Indolent Lymphoma

Patients with relapsed or refractory follicular or marginal zone lymphoma who have received at least one prior line of therapy will receive Copanlisib IV: day 1, 8, 15 every 28 days Nivolumab IV: Cycle 1 days 1 and 15; then day 1 only Rituximab IV: Cycle 1 days 1, 8, …

replacement therapy
cyp3a4 inducers
investigational treatment
pulmonary disease
ulcerative
University of Michigan Comprehensive Cancer Center
 (6.1 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location
Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer ALCHEMIST Chemo-IO Study

This phase III ALCHEMIST trial compares the addition of pembrolizumab to usual chemotherapy versus usual chemotherapy for the treatment of stage IB, II, or IIIA non-small cell lung cancer that has been removed by surgery. Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the …

egfr exon 19 deletion
non-small cell lung cancer
cisplatin/gemcitabine
pemetrexed
stage iia lung squamous cell carcinoma ajcc v7
Saint Joseph Mercy Hospital
 (0.7 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +358 other locations
NA-831 Atazanavir and Dexamethasone Combination Therapy for the Treatment of COVID-19 Infection

This Phase 2/3 trial evaluates four treatment strategies for non-critically ill hospitalized participants (not requiring ICU admission and/or mechanical ventilation) with SARS CoV-2 infection, in which participants will receive NA-831 or Atazanavir with or without Dexamethasone.

intrauterine device (iud)
acute respiratory syndrome (sars)
complete blood count
electrocardiogram (ecg)
critical illness
Coronavirus Research Institute-Testing Site
 (6.1 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +29 other locations
Effect of Academic Detailing to Reduce Opioid Prescribing in Dentistry

The purpose of this project is to improve quality of care for dental patients in the state of Michigan. This will be achieved through educating dentists about best practices for opioid prescribing and includes three continuing education (CE) credits and one (or two) academic detailing (AD) visits. The cohort of …

opioid
Chad Brummett
 (3.6 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location
THE ALIGN-AR PIVOTAL TRIAL: JenaValve Pericardial TAVR Aortic Regurgitation Study

To collect information about treatment for symptomatic severe Aortic Regurgitation (AR), which affects the aortic valve in the heart. Aortic regurgitation is a condition where aortic valve in the heart does not close tightly and allows some blood to leak back into the heart chamber. Symptoms of aortic regurgitation may …

fatigue
regurgitation
shortness of breath
aortic valve replacement
University of Michigan
 (6.1 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +9 other locations
Identification of Predictors for Clinical Outcomes in Femoroacetabular Impingement Surgery

The overarching goal of the study is to improve the surgical treatment outcomes of FAI, which is affecting an increasing number of military personnel and young active individuals in the general population. The proposed study will investigate critical patient, disease, and surgical treatment predictors of FAI surgery outcomes.

arthroscopy
femoroacetabular impingement
conservative management
hip arthroscopy
University of Michigan
 (0.7 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +11 other locations