Catonsville, Maryland Clinical Trials

A listing of Catonsville, Maryland clinical trials actively recruiting patient volunteers.

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Found 72 clinical trials
Phase 2 Clinical Trial of Crizotinib for Children and Adults With Neurofibromatosis Type 2 and Progressive Vestibular Schwannomas

Subjects with Neurofibromatosis Type 2 (NF2) and progressive vestibular schwannoma (VS) will be treated with crizotinib administered orally. Crizotinib will be taken continuously until disease progression or unacceptable toxicity, in continuous treatment cycles of 28 days each, for a maximum of 12 cycles.

crizotinib
neutrophil count
schwartz
nf2 gene
measurable disease
Johns Hopkins University (Site 250)
 (7.9 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +16 other locations
Early Bactericidal Activity of Standard Drugs Used to Treat Mycobacterium Avium Complex: a Pilot Study

To assess the early bactericidal activity of Azithromycin 250mg by mouth daily over the first 14 days of treatment for Mycobacterium avium complex (MAC) lung disease.

azithromycin
azithormycin
mycobacterium avium complex infection
mycobacterial infections
pulmonary disease
Johns Hopkins University School of Medicine
 (9.9 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location
Ablation Versus Medical Management of Atrial Fibrillation in HFpEF

This is a prospective non-blinded randomized control pilot study comparing the effect of pulmonary vein isolation against medical management of atrial fibrillation in patients with Heart Failure with preserved Ejection Fraction (HFpEF).

hypertrophy
heart failure
diuretics
persistent atrial fibrillation
cardioversion
Johns Hopkins Hospital
 (7.9 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location
Infliximab and Intravenous Immunoglobulin Therapy in Treating Patients With Steroid-Refractory Pneumonitis

This phase II trial studies how well infliximab and intravenous immunoglobulin therapy work in treating patients with pneumonitis that does not respond to steroid treatment. Immunotherapy with monoclonal antibodies such as, infliximab, may induce changes in body's immune system and may interfere with the ability of tumor cells to grow …

malignant solid neoplasm
steroid-refractory pneumonitis
monoclonal antibodies
hysterectomy
immunoglobulins
Jarushka Naidoo
 (9.6 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location
A Study to Evaluate Efficacy and Safety of PTC299 in Hospitalized Participants With Coronavirus (COVID-19)

This is a randomized, double-blind, placebo-controlled, multicenter, 28-day study of adult participants hospitalized with COVID-19, with a safety follow-up telephone call at Day 60.

oxygen saturation
vasectomy
SARS
covid-19
acute respiratory syndrome (sars)
Johns Hopkins Hospital
 (7.9 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +4 other locations
Intravesical Gemcitabine and Docetaxel for BCG na ve Non-muscle Invasive Bladder Cancer

A single-arm, two-stage, open-label, phase 2 study investigating the safety and efficacy of intravesical gemcitabine/docetaxel for bacillus Calmette-Guerin (BCG)-nave patients with non-muscle invasive bladder cancer (NMIBC). All participants will receive an induction course of gemcitabine/docetaxel instillations followed by maintenance instillations if initial efficacy is seen. In addition to providing initial …

recurrent tumor
bladder cancer
carcinoma in situ
intravesical bcg therapy
hysterectomy
Johns Hopkins University: Sidney Kimmel Comprehensive Cancer Center
 (7.9 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location
Adenosine Receptor Antagonist Combination Therapy for Metastatic Castrate Resistant Prostate Cancer

This is a Phase 1b/2, open-label, multicenter platform trial to evaluate the antitumor activity and safety of AB928-based combination therapy in participants with metastatic castrate resistant prostate cancer (mCRPC).

testosterone
antiandrogens
combined modality therapy
prostatic neoplasm
cancer
Johns Hopkins University
 (7.9 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +21 other locations
Combining H1-Coil Deep Transcranial Magnetic Stimulation (dTMS) and App-guided CBT in Subjects With Major Depression Disorder (MDD)

A naturalistic study design, in which dTMS patients will be randomized to get a free add-on CBT treatment. The dTMS procedure will include treatment as usual, and participants will use the app from post randomization (Pre-treatment is defined as measures from the first three days of treatment) to the end …

Greenbrook - Columbia
 (7.4 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +21 other locations
PPMI 2.0 Clinical -Establishing a Deeply Phenotyped PD Cohort

The Parkinson Progression Marker Initiative 2.0 (PPMI 2.0) is a longitudinal, observational, multi-center natural history study to assess progression of clinical features, digital outcomes, and imaging, biologic and genetic markers of Parkinson's disease (PD) progression in study participants with manifest PD, prodromal PD, and healthy controls The overall goal of …

muscle rigidity
alpha-synuclein
modafinil
resting tremor
bradykinesia
John Hopkins University
 (7.9 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +45 other locations
Proton Radiation Therapy Registry

The Johns Hopkins Proton Therapy center is establishing a registry to capture the full 3D radiation dosimetry delivered to the patient, baseline clinical data, and disease, toxicity and quality of life outcomes. The goal is to have all patients treated at the proton center to be included in the registry …

Johns Hopkins Hospital
 (7.9 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +3 other locations