Woburn, Massachusetts Clinical Trials

A listing of Woburn, Massachusetts clinical trials actively recruiting patient volunteers.

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Found 79 clinical trials
JSI-1187-01 Monotherapy and in Combination With Dabrafenib for Advanced Solid Tumors With MAPK Pathway Mutations

This is a Phase 1 study of JSI-1187 as monotherapy and in combination with dabrafenib for the treatment of advanced solid tumors with MAPK pathway mutations, including mutations that cause MAPK pathway hyperactivation.

neutrophil count
non-small cell lung cancer
small cell lung cancer
melanoma
metastatic melanoma
Massachusetts General Hospital Cancer Center
 (9.4 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +3 other locations
A Study of LY3819253 (LY-CoV555) in Participants With Mild to Moderate COVID-19 Illness

The purpose of this study is to measure how well LY3819253 works against the virus that causes COVID-19. LY3819253 will be given to participants with early symptoms of COVID-19, via an injection into a vein. Samples will be taken from the back of the nose to determine how much virus …

sickle cell anemia
malaise
throat
chronic disease
immunosuppressive agents
Massachusetts General Hospital
 (9.4 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +61 other locations
A Clinical Study to Assess the Physiologic Effects of KB109 in Patients With COVID-19 on Gut Microbiota Structure and Function

This exploratory, open-label clinical study aims to explore the physiologic effects of KB109, a novel glycan, on adult patients with COVID-19 illness on gut microbiota structure and function in the outpatient setting.

Massachusetts General Hospital
 (9.4 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location
Wellbeing Stress Reduction and Social Cognition

There are many ways to improve wellbeing. This study will compare two 8-week wellbeing training programs. In addition to looking at how well the programs reduce stress and enhance wellbeing, the investigators will also ask questions about how these programs influence cognition and decision making.

MGH
 (8.5 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location
A Study of Tirzepatide (LY3298176) Compared With Dulaglutide on Major Cardiovascular Events in Participants With Type 2 Diabetes

The purpose of the trial is to assess the efficacy and safety of tirzepatide to dulaglutide in participants with type 2 diabetes and increased cardiovascular risk.

cardiovascular disease
tirzepatide
body mass index
dulaglutide
Joslin Diabetes Center
 (9.8 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +650 other locations
Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer ALCHEMIST Chemo-IO Study

This phase III ALCHEMIST trial compares the addition of pembrolizumab to usual chemotherapy versus usual chemotherapy for the treatment of stage IB, II, or IIIA non-small cell lung cancer that has been removed by surgery. Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the …

non-small cell carcinoma
neutrophil count
lung non-small cell squamous carcinoma
non-small cell lung cancer
small cell lung cancer
Lahey Hospital and Medical Center
 (2.3 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +358 other locations
A Phase 3 Study to Evaluate Efficacy and Safety of AL001 in Frontotemporal Dementia (INFRONT-3)

A phase 3 double blind, placebo controlled study evaluating the efficacy and safety of AL001 in participants at risk for or with frontotemporal dementia due to heterozygous mutations in the progranulin gene.

progranulin
pick's disease
aphasia
dementia
Massachusetts General Hospital
 (9.4 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +46 other locations
NA-831 Atazanavir and Dexamethasone Combination Therapy for the Treatment of COVID-19 Infection

This Phase 2/3 trial evaluates four treatment strategies for non-critically ill hospitalized participants (not requiring ICU admission and/or mechanical ventilation) with SARS CoV-2 infection, in which participants will receive NA-831 or Atazanavir with or without Dexamethasone.

electrocardiogram (ecg)
critically ill
electrocardiogram
dexamethasone
intrauterine device (iud)
Coronavirus Research Institute-Testing Site
 (9.4 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +29 other locations
A Study of Lasmiditan (LY573144) Treatment in Children Aged 6 to 17 With Migraine

The reason for this study is to see if lasmiditan is safe and effective in children aged 6 to 17 with migraine. The study will last up to 20 weeks and may include up to 4 visits.

preventive medication
ly573144
treatment regimen
lasmiditan
headache
MedVadis Research Corp
 (7.9 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +162 other locations
A Clinical Trial of Pembrolizumab (MK-3475) Evaluating Predictive Biomarkers in Subjects With Advanced Solid Tumors (KEYNOTE 158)

In this study, participants with multiple types of advanced (unresectable and/or metastatic) solid tumors who have progressed on standard of care therapy will be treated with pembrolizumab (MK-3475).

Call for Information (Investigational Site 0010)
 (9.8 away) Contact site
  • 0 views
  • 20 Jul, 2022
  • +23 other locations