Waltham, Massachusetts Clinical Trials

A listing of Waltham, Massachusetts clinical trials actively recruiting patient volunteers.

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Found 108 clinical trials
Wellbeing Stress Reduction and Social Cognition

There are many ways to improve wellbeing. This study will compare two 8-week wellbeing training programs. In addition to looking at how well the programs reduce stress and enhance wellbeing, the investigators will also ask questions about how these programs influence cognition and decision making.

MGH
 (9.3 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location
Efficacy and Safety of Teicoplanin in CDAD

Primary Objective: Explore the efficacy of teicoplanin (100-200 mg administered orally twice a day for 7 to 14 days) in patients with Clostridium difficile infection-associated diarrhea and colitis Secondary Objective: Evaluate the safety of teicoplanin in patients with Clostridium difficile infection-associated diarrhea and colitis

Boston Medical Center
 (9.8 away) Contact site
  • 0 views
  • 04 Dec, 2020
  • +5 other locations
A Study of Tirzepatide (LY3298176) Compared With Dulaglutide on Major Cardiovascular Events in Participants With Type 2 Diabetes

The purpose of the trial is to assess the efficacy and safety of tirzepatide to dulaglutide in participants with type 2 diabetes and increased cardiovascular risk.

cardiovascular disease
tirzepatide
dulaglutide
body mass index
Joslin Diabetes Center
 (8.2 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +650 other locations
Durvalumab With or Without Olaparib as Maintenance Therapy After First-Line Treatment of Advanced and Recurrent Endometrial Cancer

A study to assess the efficacy and safety of durvalumab in combination with platinum-based chemotherapy (paclitaxel + carboplatin) followed by maintenance durvalumab with or without olaparib for patients with newly diagnosed advanced or recurrent endometrial cancer.

carboplatin
adjuvant
paclitaxel
measurable disease
recurrent endometrial cancer
Research Site
 (9.9 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +94 other locations
Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer ALCHEMIST Chemo-IO Study

This phase III ALCHEMIST trial compares the addition of pembrolizumab to usual chemotherapy versus usual chemotherapy for the treatment of stage IB, II, or IIIA non-small cell lung cancer that has been removed by surgery. Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the …

carboplatin
stage iia lung squamous cell carcinoma ajcc v7
pembrolizumab
paclitaxel
monoclonal antibody therapy
Lahey Hospital and Medical Center
 (6.6 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +358 other locations
Pre- Versus Sub-pectoral Implant-based Breast Reconstruction After Skin-sparing Mastectomy or Nipple-sparing Mastectomy OPBC-02PREPEC

This trial is to investigate whether pre-pectoral Implant-Based Breast Reconstruction (IBBR) provides better Quality of Life (QoL) with respect to long-term (24 months) physical well-being (chest) compared to sub-pectoral IBBR for patients undergoing skin-sparing mastectomy or nipple-sparing mastectomy for prevention or treatment of breast cancer.

breast cancer
breast reconstruction
mastectomy
cancer
Brigham and Women's Hospital Harvard Medical School
 (8.9 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +20 other locations
A Study of Donanemab (LY3002813) in Participants With Early Alzheimer's Disease (TRAILBLAZER-ALZ 2)

The reason for this study is to see how safe and effective the study drug donanemab is in participants with early Alzheimer's disease.

alzheimer's disease
mini-mental state examination
florbetapir
flortaucipir
positron emission tomography
Boston Center for Memory
 (7.2 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +85 other locations
A Phase 3 Study to Evaluate Efficacy and Safety of AL001 in Frontotemporal Dementia (INFRONT-3)

A phase 3 double blind, placebo controlled study evaluating the efficacy and safety of AL001 in participants at risk for or with frontotemporal dementia due to heterozygous mutations in the progranulin gene.

progranulin
dementia
aphasia
pick's disease
Massachusetts General Hospital
 (9.5 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +46 other locations
NA-831 Atazanavir and Dexamethasone Combination Therapy for the Treatment of COVID-19 Infection

This Phase 2/3 trial evaluates four treatment strategies for non-critically ill hospitalized participants (not requiring ICU admission and/or mechanical ventilation) with SARS CoV-2 infection, in which participants will receive NA-831 or Atazanavir with or without Dexamethasone.

cervical cap
acute respiratory syndrome (sars)
complete blood count
critically ill
electrocardiogram
Coronavirus Research Institute-Testing Site
 (9.5 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +29 other locations
A Study of Lasmiditan (LY573144) Treatment in Children Aged 6 to 17 With Migraine

The reason for this study is to see if lasmiditan is safe and effective in children aged 6 to 17 with migraine. The study will last up to 20 weeks and may include up to 4 visits.

ly573144
lasmiditan
migraine
headache
preventive medication
MedVadis Research Corp
 (0.8 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +162 other locations