Houston, Louisiana Clinical Trials

A listing of Houston, Louisiana clinical trials actively recruiting patient volunteers.

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Found 97 clinical trials
A Study of Donanemab (LY3002813) in Participants With Early Alzheimer's Disease (TRAILBLAZER-ALZ 2)

The reason for this study is to see how safe and effective the study drug donanemab is in participants with early Alzheimer's disease.

positron emission tomography
florbetapir
alzheimer's disease
flortaucipir
mini-mental state examination
Houston Methodist Research Ins
 (4.1 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +85 other locations
A Phase 3 Study to Evaluate Efficacy and Safety of AL001 in Frontotemporal Dementia (INFRONT-3)

A phase 3 double blind, placebo controlled study evaluating the efficacy and safety of AL001 in participants at risk for or with frontotemporal dementia due to heterozygous mutations in the progranulin gene.

pick's disease
progranulin
dementia
aphasia
Houston Methodist Institute for Academic Medicine
 (4.1 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +46 other locations
NA-831 Atazanavir and Dexamethasone Combination Therapy for the Treatment of COVID-19 Infection

This Phase 2/3 trial evaluates four treatment strategies for non-critically ill hospitalized participants (not requiring ICU admission and/or mechanical ventilation) with SARS CoV-2 infection, in which participants will receive NA-831 or Atazanavir with or without Dexamethasone.

complete blood count
cervical cap
combination therapy
electrocardiogram (ecg)
acute respiratory syndrome (sars)
Coronavirus Research Institute-Testing Site
 (4.1 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +29 other locations
Lifestyle Intervention for the Reduction of Prostate Cancer Disparities Among African Americans

This trial studies how well a lifestyle intervention works in reducing prostate cancer disparities among African American prostate cancer patients and their spouses or romantic partners. A lifestyle intervention may help researchers learn if social support can help African American prostate cancer patients and their partners improve their quality of …

stage iia prostate cancer
stage iii prostate cancer
stage i prostate cancer
stage i prostate cancer ajcc v8
stage ii prostate cancer ajcc v8
M D Anderson Cancer Center
 (4.1 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location
Bintrafusp Alfa and Stereotactic Body Radiation Therapy for the Treatment of Recurrent or Second Primary Head and Neck Squamous Cell Cancer

This phase I/II trial studies the side effects and how well bintrafusp alfa and stereotactic body radiation therapy work in treating patients with head and neck squamous cell cancer that has come back (recurrent) or has occurred after having cancer in the past (second primary). Immunotherapy with bintrafusp alfa may …

blood transfusion
serum pregnancy test
ct scan
recurrent head and neck squamous cell cancer
squamous cell carcinoma of head and neck
M D Anderson Cancer Center
 (4.1 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location
An Efficacy and Safety Study of Ravulizumab in ALS Participants

The purpose of the study is to assess the efficacy and safety of ravulizumab for the treatment of adult participants with ALS.

vaccination
riluzole
ravulizumab
edaravone
Nerve & Muscle Center of Texas
 (4.1 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +6 other locations
FT596 as a Monotherapy and in Combination With Anti-CD20 Monoclonal Antibodies

This is a Phase I dose-finding study of FT596 as monotherapy and in combination with Rituximab or Obinutuzumab in subjects with relapsed/refractory B-cell Lymphoma or Chronic Lymphocytic Leukemia. The study will consist of a dose-escalation stage and an expansion stage where participants will be enrolled into indication-specific cohorts.

leukemia
lymphoma
treatment regimen
refractory b-cell non-hodgkin lymphoma
immunochemotherapy
MD Anderson Cancer Center
 (4.1 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +2 other locations
Early Feasibility Study: Fetoscopic NEOX Cord 1K Myelomeningocele (MMC) Repair

The purpose of this study is to test the feasibility of surgically covering myelomeningocele spina bifida spinal cord developmental defects using Neox Cord 1K, cryopreserved human umbilical cords, via a laparotomy-fetoscopic surgical approach. Intact repair of the defect, prevention of cerebral spinal fluid leakage and wound dehiscence will be assessed …

spinal cord disease
myelomeningocele
spina bifida
kyphosis
body mass index
The University of Texas Health Science Center at Houston
 (4.1 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location
A Study of Oral Tazemetostat in Subjects With Moderate and Severe Hepatic Impairment With Advanced Malignancies

This is a phase 1, 2-part, global, multicenter, open-label, PK, safety and tolerability study of oral tazemetostat in subjects with either advanced solid tumors, or hematological malignancies and normal hepatic function or moderate, or severe hepatic impairment.

malabsorption
malabsorption syndrome
oral contraception
hemolysis
lymphoma
Oncology Consultants - Texas Medical Center
 (4.1 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +4 other locations
A Study of ASTX030 (Cedazuridine in Combination With Azacitidine) in MDS CMML or AML

Study ASTX030-01 is designed to move efficiently from Phase 1 to Phase 3. Phase 1 consists of an open-label Dose Escalation Stage (Stage A) using multiple cohorts at escalating dose levels of oral cedazuridine and azacitidine (only one study drug will be escalated at a time) followed by a Dose …

neutropenia
immunosuppressive agents
leukemia
acute leukemia
immunosuppression
MD Anderson Cancer Center
 (4.1 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +1 other locations