Durate, Illinois Clinical Trials

A listing of Durate, Illinois clinical trials actively recruiting patient volunteers.

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Found 71 clinical trials
Safety and Efficacy of AT-527 in Subjects With Moderate Coronavirus Disease (COVID-19)

The objectives of this study are to evaluate the safety, tolerability and efficacy of AT-527 in older subjects (ages 45-80 years) with moderate COVID-19 and risk factors for poor outcomes (such as obesity (BMI>30), hypertension, diabetes or asthma). Eligible subjects will be randomized to blinded AT-527 (nucleotide analog) tablets or …

SARS
hypertension
acute respiratory syndrome (sars)
asthma
coronavirus infection
Atea Study Site
 (4.1 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +9 other locations
A Study of LY3819253 (LY-CoV555) in Participants With Mild to Moderate COVID-19 Illness

The purpose of this study is to measure how well LY3819253 works against the virus that causes COVID-19. LY3819253 will be given to participants with early symptoms of COVID-19, via an injection into a vein. Samples will be taken from the back of the nose to determine how much virus …

renal disease
immunosuppressive agents
pharyngitis
throat
sore throat
J H. Stroger Hosp of Cook Co
 (4.1 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +61 other locations
Unacylated Ghrelin to Improve Functioning in PAD

GIFT is a pilot, randomized, double-blinded clinical trial that will examine the effects of unacylated ghrelin on walking ability in people with peripheral artery disease (PAD) compared to placebo. Preliminary evidence suggests that unacylated ghrelin may improve blood flow to the extremities and promote improved skeletal muscle growth and energy …

peripheral artery disease
ghrelin
arteriopathy
peripheral arterial diseases
Northwestern University Feinberg School of Medicine
 (7.1 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location
A Study to Evaluate the Efficacy of Sage-217 in the Treatment of Adult Participants With Major Depressive Disorder (MDD)

The purpose of this study to evaluate the efficacy of SAGE-217 in the treatment of participants with MDD.

psychiatric disorder
major depressive disorder
scid
depression
antidepressants
Sage Investigational Site
 (7.1 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +35 other locations
A Study of Tirzepatide (LY3298176) Compared With Dulaglutide on Major Cardiovascular Events in Participants With Type 2 Diabetes

The purpose of the trial is to assess the efficacy and safety of tirzepatide to dulaglutide in participants with type 2 diabetes and increased cardiovascular risk.

dulaglutide
body mass index
tirzepatide
cardiovascular disease
Cedar-Crosse Research Center
 (6.1 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +650 other locations
PATH 2 Purpose: Primary Care and Community-Based Prevention of Mental Disorders in Adolescents

The study is a two-arm comparative effectiveness research trial to that will evaluate the ability of the interventions, Competent Adulthood Transition with Cognitive-behavioral & Interpersonal Training (CATCH-IT) and Teens Achieving Mastery over Stress (TEAMS), to intervene early to prevent depressive illness and potentially other common mental health disorders. Using cluster …

depressive symptoms
psychiatric disorder
depressive disorder
UI Health
 (4.1 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location
A Study of Donanemab (LY3002813) in Participants With Early Alzheimer's Disease (TRAILBLAZER-ALZ 2)

The reason for this study is to see how safe and effective the study drug donanemab is in participants with early Alzheimer's disease.

positron emission tomography
florbetapir
alzheimer's disease
flortaucipir
mini-mental state examination
Great Lakes Clinical Trials
 (5.4 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +85 other locations
A Phase 3 Study to Evaluate Efficacy and Safety of AL001 in Frontotemporal Dementia (INFRONT-3)

A phase 3 double blind, placebo controlled study evaluating the efficacy and safety of AL001 in participants at risk for or with frontotemporal dementia due to heterozygous mutations in the progranulin gene.

pick's disease
progranulin
dementia
aphasia
Northwestern University
 (7.1 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +46 other locations
NA-831 Atazanavir and Dexamethasone Combination Therapy for the Treatment of COVID-19 Infection

This Phase 2/3 trial evaluates four treatment strategies for non-critically ill hospitalized participants (not requiring ICU admission and/or mechanical ventilation) with SARS CoV-2 infection, in which participants will receive NA-831 or Atazanavir with or without Dexamethasone.

complete blood count
cervical cap
combination therapy
electrocardiogram (ecg)
acute respiratory syndrome (sars)
Coronavirus Research Institute- Testing Site
 (4.1 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +29 other locations
2019-06 TRISCEND Study

Early feasibility study to assess safety and performance of the Edwards EVOQUE Tricuspid Valve Replacement System

medical therapy
tricuspid valve replacement
Northwestern University
 (9.7 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +6 other locations