Chicago, Illinois Clinical Trials

A listing of Chicago, Illinois clinical trials actively recruiting patient volunteers.

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Found 75 clinical trials
Tipifarnib for the Treatment of Advanced Solid Tumors Lymphoma or Histiocytic Disorders With HRAS Gene Alterations a Pediatric MATCH Treatment Trial

This phase II pediatric MATCH trial studies how well tipifarnib works in treating patients with solid tumors that have spread to other places in the body (advanced), lymphoma, or histiocytic disorders that have HRAS genetic alterations. Tipifarnib may block the growth of cancer cells that have specific genetic changes in …

pegfilgrastim
bone marrow procedure
cancer
blood count
antineoplastic
University of Chicago Comprehensive Cancer Center
 (7.3 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +82 other locations
Phase 2 Clinical Trial of Crizotinib for Children and Adults With Neurofibromatosis Type 2 and Progressive Vestibular Schwannomas

Subjects with Neurofibromatosis Type 2 (NF2) and progressive vestibular schwannoma (VS) will be treated with crizotinib administered orally. Crizotinib will be taken continuously until disease progression or unacceptable toxicity, in continuous treatment cycles of 28 days each, for a maximum of 12 cycles.

measurable disease
crizotinib
schwartz
glioma
neutrophil count
Lurie Children's Hospital of Chicago (Site 350)
 (0.5 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +16 other locations
Safety and Efficacy of Samsung GEMS-H Device Training in Sub-Acute and Chronic Stroke

A single-site, interventional, single-arm trial to evaluate the safety and efficacy on functional mobility following Samsung GEMS-H (Gait Enhancing and Motivating System - Hip) device training in participants with sub-acute and chronic stroke.

chronic stroke
stroke
chronic cerebrovascular accident
mini-mental state examination
Shirley Ryan AbilityLab
 (0.5 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location
Adenosine Receptor Antagonist Combination Therapy for Metastatic Castrate Resistant Prostate Cancer

This is a Phase 1b/2, open-label, multicenter platform trial to evaluate the antitumor activity and safety of AB928-based combination therapy in participants with metastatic castrate resistant prostate cancer (mCRPC).

prostate cancer
antiandrogens
measurable disease
cancer
combined modality therapy
Northwestern University Feinberg School of Medicine
 (0.5 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +21 other locations
Clinical and Genetic Analysis of ROP

Retinopathy of Prematurity (ROP) is a vascular disease affecting the retinas (back of the eye) of low birth weight infants. Although it can be treated effectively if diagnosed early, it continues to be a leading cause of childhood blindness in the United States and throughout the world. The investigators feel …

vascular disease
premature birth
prematurity
genetic analysis
pediatric
University of Illinois Chicago
 (1.9 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +4 other locations
PPMI 2.0 Clinical -Establishing a Deeply Phenotyped PD Cohort

The Parkinson Progression Marker Initiative 2.0 (PPMI 2.0) is a longitudinal, observational, multi-center natural history study to assess progression of clinical features, digital outcomes, and imaging, biologic and genetic markers of Parkinson's disease (PD) progression in study participants with manifest PD, prodromal PD, and healthy controls The overall goal of …

bradykinesia
genetic testing
resting tremor
muscle rigidity
methyldopa
Northwestern University
 (0.5 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +45 other locations
International Collaborative Gaucher Group (ICGG) Gaucher Disease Registry & Pregnancy Sub-registry

The ICGG Gaucher Registry is an ongoing, international multi-center, strictly observational program that tracks the routine clinical outcomes for patients with Gaucher disease, irrespective of treatment status. No experimental intervention is involved; patients in the Registry undergo clinical assessments and receive care as determined by the patient's treating physician. The …

gaucher disease
eliglustat
deficiency
imiglucerase
Investigational Site Number 840011
 (0.5 away) Contact site
  • 0 views
  • 04 Dec, 2020
  • +208 other locations
Mucopolysaccharidosis I (MPS I) Registry

The Mucopolysaccharidosis I (MPS I) Registry is an ongoing, observational database that tracks the outcomes of patients with MPS I. The data collected by the MPS I Registry will provide information to better characterize the natural history and progression of MPS I as well as the clinical responses of patients …

Investigational Site Number 840011
 (0.5 away) Contact site
  • 0 views
  • 04 Dec, 2020
  • +124 other locations
Pompe Disease Registry

The Pompe Registry is an ongoing, international multi-center, strictly observational program that tracks the routine clinical outcomes for patients with Pompe disease, irrespective of treatment status. No experimental intervention is involved; patients in the Registry undergo clinical assessments and receive care as determined by the patient's treating physician. The objectives …

glycogen storage disease type ii
gaa gene
myozyme
replacement therapy
deficiency
Investigational Site Number 840011
 (0.5 away) Contact site
  • 0 views
  • 22 Dec, 2020
  • +168 other locations
Fabry Disease Registry & Pregnancy Sub-registry

The Fabry Registry is an ongoing, international multi-center, strictly observational program that tracks the routine clinical outcomes for patients with Fabry disease, irrespective of treatment status. No experimental intervention is involved; patients in the Registry undergo clinical assessments and receive care as determined by the patient's treating physician. The primary …

agalsidase beta
fabry's disease
deficiency
replacement therapy
alpha-galactosidase
Investigational Site Number 840013
 (0.5 away) Contact site
  • 0 views
  • 22 Dec, 2020
  • +125 other locations