Sandy Springs, Georgia Clinical Trials

A listing of Sandy Springs, Georgia clinical trials actively recruiting patient volunteers.

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Found 66 clinical trials
A Phase 3 Study to Evaluate Efficacy and Safety of AL001 in Frontotemporal Dementia (INFRONT-3)

A phase 3 double blind, placebo controlled study evaluating the efficacy and safety of AL001 in participants at risk for or with frontotemporal dementia due to heterozygous mutations in the progranulin gene.

aphasia
progranulin
dementia
pick's disease
Emory University
 (7.5 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +46 other locations
Platinum-Based Chemotherapy and Durvalumab for the Treatment of Stage IIIB or IV Non-small Cell Lung Cancer

This phase II trial studies how well platinum-based chemotherapy works when given together with durvalumab in treating patients with stage IIIB or stage IV non-small cell lung cancer. Drugs used in chemotherapy, such as carboplatin, paclitaxel, and pemetrexed, work in different ways to stop the growth of tumor cells, either …

endocrine therapy
pemetrexed
monoclonal antibodies
crohn's disease
granulomatosis
Emory University Hospital Midtown
 (9.5 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +1 other locations
Tipifarnib for the Treatment of Advanced Solid Tumors Lymphoma or Histiocytic Disorders With HRAS Gene Alterations a Pediatric MATCH Treatment Trial

This phase II pediatric MATCH trial studies how well tipifarnib works in treating patients with solid tumors that have spread to other places in the body (advanced), lymphoma, or histiocytic disorders that have HRAS genetic alterations. Tipifarnib may block the growth of cancer cells that have specific genetic changes in …

refractory peripheral primitive neuroectodermal tumor
cancer therapy
radiopharmaceutical
cytokines
recurrent melanoma
Children's Healthcare of Atlanta - Egleston
 (9.5 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +82 other locations
Phase 2 Clinical Trial of Crizotinib for Children and Adults With Neurofibromatosis Type 2 and Progressive Vestibular Schwannomas

Subjects with Neurofibromatosis Type 2 (NF2) and progressive vestibular schwannoma (VS) will be treated with crizotinib administered orally. Crizotinib will be taken continuously until disease progression or unacceptable toxicity, in continuous treatment cycles of 28 days each, for a maximum of 12 cycles.

neutrophil count
nf2 gene
neurofibroma
cataract
crizotinib
Children's HealthCare of Atlanta (Site 950)
 (7.8 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +16 other locations
Cognitive Behavioral Therapy for Insomnia for the Dementia Caregiving Dyad

Disturbed sleep is stressful to persons living with dementia (PLwD) and their caregivers. It contributes to earlier placement of the PLwD in nursing homes and increase the risk for many psychological and cognitive health issues and poor quality of life for both the PLwD and the caregivers. Given the potential …

sleep disorder
actigraphy
behavior modification
psychotropic drugs
hearing impairment
Goizueta Alzheimer's Disease Research Center
 (7.5 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +1 other locations
THE ALIGN-AR PIVOTAL TRIAL: JenaValve Pericardial TAVR Aortic Regurgitation Study

To collect information about treatment for symptomatic severe Aortic Regurgitation (AR), which affects the aortic valve in the heart. Aortic regurgitation is a condition where aortic valve in the heart does not close tightly and allows some blood to leak back into the heart chamber. Symptoms of aortic regurgitation may …

fatigue
regurgitation
shortness of breath
aortic valve replacement
Piedmont Healthcare
 (9.2 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +9 other locations
Best Supportive Care With or Without Low Dose Whole Lung Radiation Therapy for the Treatment of COVID-19

This phase III trial compares low dose whole lung radiation therapy to best supportive care plus physicians choice in treating patients with COVID-19 infection. Low dose whole lung radiation therapy may work better than the current best supportive care and physician's choice in improving patients' clinical status, the radiographic appearance …

acute respiratory syndrome (sars)
chest imaging
cough
dyspnea
blood tests
Emory University Hospital/Winship Cancer Institute
 (9.5 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location
Lenvatinib and Pembrolizumab Before Surgery for the Treatment of Locally Advanced Non-Metastatic Kidney Cancer

This phase II trial studies how well lenvatinib and pembrolizumab before surgery work in treating patients with kidney cancer that has spread from its original site of growth to nearby tissues or lymph nodes but has not spread to other places in the body (non-metastatic). Lenvatinib may stop the growth …

bilirubin levels
monoclonal antibodies
beta human chorionic gonadotrophin
metastatic renal cell carcinoma
conjugated bilirubin
Emory University Hospital/Winship Cancer Institute
 (9.5 away) Contact site
  • 8 views
  • 05 Aug, 2020
  • 1 location
PPMI 2.0 Clinical -Establishing a Deeply Phenotyped PD Cohort

The Parkinson Progression Marker Initiative 2.0 (PPMI 2.0) is a longitudinal, observational, multi-center natural history study to assess progression of clinical features, digital outcomes, and imaging, biologic and genetic markers of Parkinson's disease (PD) progression in study participants with manifest PD, prodromal PD, and healthy controls The overall goal of …

modafinil
genetic testing
muscle rigidity
datscan
tremor
Emory University School of Medicine
 (7.5 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +45 other locations
International Collaborative Gaucher Group (ICGG) Gaucher Disease Registry & Pregnancy Sub-registry

The ICGG Gaucher Registry is an ongoing, international multi-center, strictly observational program that tracks the routine clinical outcomes for patients with Gaucher disease, irrespective of treatment status. No experimental intervention is involved; patients in the Registry undergo clinical assessments and receive care as determined by the patient's treating physician. The …

gaucher disease
deficiency
eliglustat
imiglucerase
Investigational Site Number 840060
 (9.9 away) Contact site
  • 0 views
  • 04 Dec, 2020
  • +208 other locations