Decatur, Georgia Clinical Trials

A listing of Decatur, Georgia clinical trials actively recruiting patient volunteers.

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Found 69 clinical trials
Study to Evaluate the Effect of GBT440 on TCD in Pediatrics With Sickle Cell Disease

This study is a Phase 3, randomized, double-blind, placebo-controlled study of voxelotor in pediatric participants, aged 2 to < 15 years old, with Sickle Cell Disease. The primary objective is to evaluate the effect of voxelotor on the TCD (Transcranial Doppler Ultrasound) measurements in SCD participants in this age range.

gbt440
anemia
cerebral blood flow
transcranial doppler ultrasonography
pediatric
Children's Healthcare of Atlanta-Hughes Spalding
 (5.4 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +34 other locations
Outcome Study Assessing a 75 Milligrams (mg) Dose of Macitentan in Patients With Pulmonary Arterial Hypertension

The purpose of this study is to demonstrate superiority of macitentan 75 milligrams (mg) in prolonging the time to the first clinical events committee (CEC)-adjudicated morbidity or mortality (M/M) event in participants with symptomatic pulmonary arterial hypertension (PAH) compared to macitentan 10 mg.

heart disease
ventricular septal defect
hemodynamic evaluation
right heart catheterization
macitentan 10 mg
Northside Hospital
 (9.1 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +210 other locations
20-valent Pneumococcal Conjugate Vaccine Safety and Immunogenicity Study of a 4-Dose Series in Healthy Infants

20-valent Pneumococcal Conjugate Vaccine Safety and Immunogenicity Study of a 4-Dose Series in Healthy Infants

pneumococcal conjugate
conjugate vaccine
Tekton Research, Inc.
 (8.9 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +46 other locations
A Study Evaluating The Safety Tolerability Pharmacokinetics And Efficacy Of Venetoclax In Combination With Atezolizumab Carboplatin And Etoposide In Participants With Untreated Extensive-Stage Small Cell Lung Cancer (ES-SCLC).

A study consisting of a dose-escalation phase and a dose-expansion phase to evaluate the safety, tolerability, pharmacokinetics, and efficacy of venetoclax in combination with atezolizumab, carboplatin, and etoposide.

g-csf
cancer therapy
etoposide
carboplatin
small cell lung cancer
Emory University
 (2.6 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +15 other locations
A Medical Research Study Designed to Determine if Venglustat Can be a Future Treatment for ADPKD Patients

Primary Objective: To determine the effect of venglustat on the rate of total kidney volume (TKV) growth (Stage and estimated glomerular filtration rate (eGFR) decline in patients at risk of rapidly progressive Autosomal Dominant Polycystic Kidney Disease (ADPKD) (Stage 2). Secondary Objectives: To determine the effect of venglustat on the …

ophthalmological examination
urine osmolality
treatment regimen
cyst
tolvaptan
Investigational Site Number 8400004
 (2.6 away) Contact site
  • 0 views
  • 04 Dec, 2020
  • +80 other locations
A Study of Tucatinib vs. Placebo in Combination With Ado-trastuzumab Emtansine (T-DM1) for Patients With Advanced or Metastatic HER2+ Breast Cancer

This study is being done to see if tucatinib with ado-trastuzumab emtansine (T-DM1) works better than T-DM1 alone to help patients who have a specific type of breast cancer called HER2 positive breast carcinoma. The breast cancer in this study is either metastatic (spread into other parts of the body) …

Winship Cancer Institute / Emory University School of Medicine
 (2.6 away) Contact site
  • 0 views
  • 14 Mar, 2022
  • +227 other locations
Implementing Models for Mechanical Circulatory Support Presurgical Assessment in Congenital Heart Disease Treatment (IMMPACT)

The purpose of this research study is to look at the advantages of using a 3D printed heart model for surgical planning in children who have been diagnosed with Congenital Heart Disease (CHD) and clinical heart failure and will undergo a ventricular assist device (VAD) placement. The investigators want to …

Children's Healthcare of Atlanta
 (2.6 away) Contact site
  • 0 views
  • 05 Jul, 2023
  • +8 other locations
Implementing Models for Mechanical Circulatory Support Presurgical Assessment in Congenital Heart Disease Treatment (IMMPACTTest123)

The purpose of this research study is to look at the advantages of using a 3D printed heart model for surgical planning in children who have been diagnosed with Congenital Heart Disease (CHD) and clinical heart failure and will undergo a ventricular assist device (VAD) placement. The investigators want to …

Children's Healthcare of Atlanta
 (2.6 away) Contact site
  • 0 views
  • 28 Mar, 2024
  • +8 other locations
Tango for Alzheimer's Disease Patients' Caregivers

The goal of the project is to determine the extent to which indices of inflammatory biomarkers, cognition and mood, are influenced by a partnered, dance-based intervention vs control condition in African American (AA) female family caregivers, at high risk for Alzheimer's disease (AD).

alzheimer's disease
Atlanta VA Medical Center, Emory University, Executive Park, Wesley Woods
 (2.6 away) Contact site
  • 24 views
  • 16 Feb, 2024
  • 1 location
A Study to Evaluate Enfortumab Vedotin in Subjects With Previously Treated Locally Advanced or Metastatic Malignant Solid Tumors (EV-202)

The primary purpose of this study is to determine the antitumor activity of enfortumab vedotin as measured by confirmed objective response rate (ORR). This study will also assess other measures of antitumor activity; overall survival (OS); as well as the safety and tolerability of enfortumab vedotin.

Piedmont Hospital
 (9.0 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +7 other locations