Orlando, Florida Clinical Trials

A listing of Orlando, Florida clinical trials actively recruiting patient volunteers.

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Found 47 clinical trials
A Study to Assess the Safety and Efficacy of a Subcutaneous Formulation of Efgartigimod in Adults With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP an Autoimmune Disorder That Affects the Peripheral Nerves)

This is a Phase 2 study to evaluate the safety and efficacy of the subcutaneous formulation of efgartigimod in adults with CIDP.

polyneuropathy
autoimmune disease
prednisone
cidp
igiv
Investigator site 9
 (2.4 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +16 other locations
Study of Atezolizumab in Combination With Cabozantinib Versus Docetaxel in Patients With Metastatic Non-Small Cell Lung Cancer Previously Treated With an Anti-PD-L1/PD-1 Antibody and Platinum-Containing Chemotherapy

This is a Phase III, multicenter, randomized, open-label study designed to evaluate the efficacy, safety, and pharmacokinetics of atezolizumab given in combination with cabozantinib compared with docetaxel monotherapy in patients with metastatic NSCLC, with no sensitizing EGFR mutation or ALK translocation, who have progressed following treatment with platinum-containing chemotherapy and …

hepatitis b surface antigen
lung cancer
stage iv non-small cell lung cancer
cancer
EGFR
Florida Hospital
 (2.8 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +97 other locations
A Study to Evaluate the Efficacy and Safety of Intravenous Prasinezumab in Participants With Early Parkinson's Disease  

This is a multicenter, randomized, double-blind, placebo-controlled study that will evaluate the efficacy and safety of intravenous (IV) prasinezumab versus placebo in participants with Early Parkinson's Disease (PD) who are on stable symptomatic PD medication.

dopamine
early parkinson's
resting tremor
parkinsonism
bradykinesia
Synexus Clinical Research
 (2.4 away)
  • 0 views
  • 28 Jun, 2022
  • +125 other locations
A Study of Tucatinib vs. Placebo in Combination With Ado-trastuzumab Emtansine (T-DM1) for Patients With Advanced or Metastatic HER2+ Breast Cancer

This study is being done to see if tucatinib with ado-trastuzumab emtansine (T-DM1) works better than T-DM1 alone to help patients who have a specific type of breast cancer called HER2 positive breast carcinoma. The breast cancer in this study is either metastatic (spread into other parts of the body) …

Orlando Health, Inc. TRIO
 (2.4 away) Contact site
  • 0 views
  • 14 Mar, 2022
  • +227 other locations
Study of Pexidartinib in Participants With Moderate Hepatic Impairment Compared With Healthy Participants

The pharmacokinetics of a single dose of pexidartinib will be investigated in participants with impaired hepatic function and compared with healthy control participants with normal hepatic function.

Orlando Clinical Research Center
 (5.7 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +1 other locations
Evaluation of the Integrated Radio Frequency Denervation System to Improve Glycemic Control in Type 2 Diabetic Subjects

The objective of this early feasibility study is to evaluate the safety and performance of intravascular hepatic denervation using the Metavention Integrated Radio Frequency Denervation System (iRF System) to improve glycemic control in type 2 diabetes subjects.

hypertension medication
liver disease
fatty liver
nash
hypertension
AdventHealth Translational Research Institute
 (2.8 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +4 other locations
A Study to Evaluate the Efficacy of Sage-217 in the Treatment of Adult Participants With Major Depressive Disorder (MDD)

The purpose of this study to evaluate the efficacy of SAGE-217 in the treatment of participants with MDD.

antidepressants
depression
scid
depressive disorder
psychotherapy
Sage Investigational Site
 (4.4 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +35 other locations
A Study of Tirzepatide (LY3298176) Compared With Dulaglutide on Major Cardiovascular Events in Participants With Type 2 Diabetes

The purpose of the trial is to assess the efficacy and safety of tirzepatide to dulaglutide in participants with type 2 diabetes and increased cardiovascular risk.

cardiovascular disease
body mass index
dulaglutide
tirzepatide
Orlando Heart & Vascular Institute, LLC
 (8.8 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +650 other locations
A Study of Donanemab (LY3002813) in Participants With Early Alzheimer's Disease (TRAILBLAZER-ALZ 2)

The reason for this study is to see how safe and effective the study drug donanemab is in participants with early Alzheimer's disease.

positron emission tomography
mini-mental state examination
florbetapir
flortaucipir
alzheimer's disease
Compass Research
 (2.4 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +85 other locations
A Study of Lasmiditan (LY573144) Treatment in Children Aged 6 to 17 With Migraine

The reason for this study is to see if lasmiditan is safe and effective in children aged 6 to 17 with migraine. The study will last up to 20 weeks and may include up to 4 visits.

lasmiditan
preventive medication
ly573144
headache
migraine
Pediatric Neurology P.A.
 (4.0 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +162 other locations