Hamden, Connecticut Clinical Trials

A listing of Hamden, Connecticut clinical trials actively recruiting patient volunteers.

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Found 54 clinical trials
A Medical Research Study Designed to Determine if Venglustat Can be a Future Treatment for ADPKD Patients

Primary Objective: To determine the effect of venglustat on the rate of total kidney volume (TKV) growth (Stage and estimated glomerular filtration rate (eGFR) decline in patients at risk of rapidly progressive Autosomal Dominant Polycystic Kidney Disease (ADPKD) (Stage 2). Secondary Objectives: To determine the effect of venglustat on the …

renal function
fatigue
tolvaptan
antihypertensive therapy
polycystic kidney disease
Investigational Site Number 8400010
 (3.9 away) Contact site
  • 0 views
  • 04 Dec, 2020
  • +80 other locations
A Study to Evaluate the Efficacy and Safety of Intravenous Prasinezumab in Participants With Early Parkinson's Disease  

This is a multicenter, randomized, double-blind, placebo-controlled study that will evaluate the efficacy and safety of intravenous (IV) prasinezumab versus placebo in participants with Early Parkinson's Disease (PD) who are on stable symptomatic PD medication.

early parkinson's
resting tremor
parkinsonism
dopamine transporter
bradykinesia
Yale University
 (2.8 away)
  • 0 views
  • 28 Jun, 2022
  • +125 other locations
Treatment of Pregnant Women With OUD

The investigators are testing two models of support for pregnant women with an opioid use disorder (OUD)

Yale New Haven Hospital Maternal Fetal Medicine Unit
 (2.8 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +11 other locations
Understanding Factors That Influence Electronic Cigarette Nicotine Delivery Through PET Imaging of Beta-2 Nicotinic Acetylcholine Receptors

The goal of this proposal is to test the overall hypothesis that e-cigarettes (ECs) provide efficient nicotine delivery to the brain and arterial blood in non-EC-nave smokers and e-cigarette users and that EC liquid characteristics modulate this effect. This study will test the hypothesis through complementary methods that include [ …

Yale University School of Medicine
 (2.8 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location
Dose Escalation Study of PF-07209326 in Healthy Participants

This Phase 1 first-in-human single ascending dose and multiple dose study will be a randomized, double-blind, placebo-controlled investigation of the safety, tolerability, and pharmacokinetics of PF-07209326.

New Haven Clinical Research Unit
 (2.8 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location
At-Risk for Type 1 Diabetes Extension Study

This study is an extension of the NIH-sponsored AT-Risk (TN-10) type 1 diabetes study (NCT 01030861). Teplizumab-treated and placebo-treated participants in the NIH trial who develop clinical type 1 diabetes after the conclusion of that trial, are eligible to enroll and receive teplizumab treatment within one year of diagnosis of …

teplizumab
type 1 diabetes mellitus
diabetes
Clinical Site
 (4.6 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +4 other locations
Effect of Cannabis Use on Synaptic Density in Older Adults

The aim of the study is to examine the effect of cannabis use on brain synaptic density among older adults using [11C]UCB-J PET imaging.

Accepts healthy volunteers
Connecticut Mental Health Center
 (4.6 away) Contact site
  • 0 views
  • 20 Jul, 2022
  • +1 other locations
A Study of Tirzepatide (LY3298176) Compared With Dulaglutide on Major Cardiovascular Events in Participants With Type 2 Diabetes

The purpose of the trial is to assess the efficacy and safety of tirzepatide to dulaglutide in participants with type 2 diabetes and increased cardiovascular risk.

body mass index
dulaglutide
tirzepatide
cardiovascular disease
CMR of Greater New Haven, LLC
 (1.9 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +650 other locations
Durvalumab With or Without Olaparib as Maintenance Therapy After First-Line Treatment of Advanced and Recurrent Endometrial Cancer

A study to assess the efficacy and safety of durvalumab in combination with platinum-based chemotherapy (paclitaxel + carboplatin) followed by maintenance durvalumab with or without olaparib for patients with newly diagnosed advanced or recurrent endometrial cancer.

adjuvant
durvalumab
endometrial carcinoma
carcinosarcoma
carcinoma
Research Site
 (3.8 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +94 other locations
A Study of Donanemab (LY3002813) in Participants With Early Alzheimer's Disease (TRAILBLAZER-ALZ 2)

The reason for this study is to see how safe and effective the study drug donanemab is in participants with early Alzheimer's disease.

florbetapir
positron emission tomography
flortaucipir
mini-mental state examination
alzheimer's disease
Institute for Neurodegenerative Disorders
 (3.9 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +85 other locations