Yorba Linda, California Clinical Trials

A listing of Yorba Linda, California clinical trials actively recruiting patient volunteers.

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Found 47 clinical trials
Fitusiran Prophylaxis in Male Pediatric Subjects Aged 1 to Less Than 12 Years With Hemophilia A or B

Primary Objective: To confirm appropriate dose levels of fitusiran when administered to male pediatric participants (ages 1 to <12 years of age) with severe hemophilia A or B Secondary Objective: To characterize the safety and tolerability To characterize the pharmacokinetics (PK)

antihemophilic factor
factor ix
severe haemophilia a
bethesda assay
haemophilia a
Investigational Site Number 8400010
 (7.9 away) Contact site
  • 0 views
  • 04 Dec, 2020
  • +5 other locations
None

Center for Inherited Blood Disorders (CIBD)-Site Number:8400001
 (7.9 away) Contact site
  • 0 views
  • 26 Sep, 2023
  • +2 other locations
A Phase 3 Safety and Efficacy Study of Intravitreal Administration of Zimura (Complement C5 Inhibitor)

The objectives of this study are to evaluate the safety and efficacy of Zimura intravitreal administration in patients with geographic atrophy secondary to age-related macular degeneration (AMD)

maculopathy
geographic atrophy
macular degeneration
atrophy
complement c5
Retina Consultants of Orange County
 (6.8 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +22 other locations
Adenosine Receptor Antagonist Combination Therapy for Metastatic Castrate Resistant Prostate Cancer

This is a Phase 1b/2, open-label, multicenter platform trial to evaluate the antitumor activity and safety of AB928-based combination therapy in participants with metastatic castrate resistant prostate cancer (mCRPC).

antiandrogens
measurable disease
testosterone
cancer
taxane
The University of California, Irvine Medical Center
 (7.9 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +21 other locations
Assessing Patient-Reported Experience of Care for Home Dialysis (ASPIRED)

Home dialysis modalities, including peritoneal dialysis (PD) and home hemodialysis (HHD), represent alternatives to conventional in-center hemodialysis (HD) that for some patients may be better aligned with preferences regarding the integration of dialysis treatments into their lives. Assessment of patient experience and satisfaction with care among individuals undergoing maintenance dialysis …

home hemodialysis
dialysis
Satellite Healthcare Orange
 (7.9 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +31 other locations
Pompe Disease Registry Protocol....

The Pompe Registry is a global, multicenter, international, longitudinal, observational, and voluntary program for patients with Pompe disease, designed to track the disease's natural history and outcomes in patients, both treated and not. Data from the Registry are also used to fulfill various global regulatory commitments, to support product development/reimbursement, …

Investigational Site Number :840074
 (7.9 away) Contact site
  • 0 views
  • 14 Mar, 2022
  • +11 other locations
Patient-Derived Xenografts to Reduce Cancer Health Disparities

This trial establishes patient-derived cancer xenografts in addressing cancer health and treatment disparities that disproportionately affect racial/ethnic minorities. Understanding the genetic and response differences among racial/ethnic minorities may help researchers enhance the precision of therapeutic treatments.

biospecimen collection
liver cancer
bladder cancer
lung cancer
gastric cancer
UC Irvine Health/Chao Family Comprehensive Cancer Center
 (7.9 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +1 other locations