Sherman Oaks, California Clinical Trials

A listing of Sherman Oaks, California clinical trials actively recruiting patient volunteers.

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Found 77 clinical trials
A Study of LY3819253 (LY-CoV555) in Participants Hospitalized for COVID-19

The purpose of this study is to test the safety and tolerability of LY3819253 when it is given by injection into a vein to participants hospitalized with COVID-19. Blood tests will be done to check how much LY3819253 is in the bloodstream and how long the body takes to eliminate …

blood test
covid-19
Cedars Sinai Medical Center
 (6.8 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +10 other locations
A Study of LY3819253 (LY-CoV555) in Participants With Mild to Moderate COVID-19 Illness

The purpose of this study is to measure how well LY3819253 works against the virus that causes COVID-19. LY3819253 will be given to participants with early symptoms of COVID-19, via an injection into a vein. Samples will be taken from the back of the nose to determine how much virus …

heart disease
dyspnea
headache
covid-19
hypertension
Cedars Sinai Medical Center
 (6.8 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +61 other locations
Quantifying Oxygen Utilization of Tumors Using Oxygen-Enhanced Molecular MRI

This trial looks to study the safety and feasibility of using oxygen-enhanced molecular MRI to understand how cancer cells use oxygen differently than normal cells. Cancer cells tend to utilize (or not utilize) oxygen differently than normal cells. By using the oxygen-enhanced molecular MRI, researchers will be able to create …

brain metastases
neoplasm
MRI
brain tumor
cancer
UCLA / Jonsson Comprehensive Cancer Center
 (5.4 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location
A Study to Evaluate the Efficacy of Sage-217 in the Treatment of Adult Participants With Major Depressive Disorder (MDD)

The purpose of this study to evaluate the efficacy of SAGE-217 in the treatment of participants with MDD.

benzodiazepines
structured clinical interview
antidepressants
psychiatric disorder
depressive disorder
Sage Investigational Site
 (0.6 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +35 other locations
High-Risk Veteran Initiative

Veterans at high-risk for hospitalization, including those with complex care needs, represent a large population of VHA patients who often do not receive evidence-based primary care practices that would help them avoid the hospital and improve their health. The high-RIsk VETerans (RIVET) Program will implement evidence-based practices that can support …

VA Greater Los Angeles Healthcare System, Sepulveda, CA
 (6.4 away) Contact site
  • 0 views
  • 21 Sep, 2021
  • +2 other locations
A Study of Tirzepatide (LY3298176) Compared With Dulaglutide on Major Cardiovascular Events in Participants With Type 2 Diabetes

The purpose of the trial is to assess the efficacy and safety of tirzepatide to dulaglutide in participants with type 2 diabetes and increased cardiovascular risk.

cardiovascular disease
body mass index
tirzepatide
dulaglutide
Valley Clinical Trials, Inc.
 (7.3 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +650 other locations
Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer ALCHEMIST Chemo-IO Study

This phase III ALCHEMIST trial compares the addition of pembrolizumab to usual chemotherapy versus usual chemotherapy for the treatment of stage IB, II, or IIIA non-small cell lung cancer that has been removed by surgery. Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the …

antiretroviral therapy
stage iiia lung cancer ajcc v7
absolute neutrophil count
platelet count
stage iia lung squamous cell carcinoma ajcc v7
Providence Saint Joseph Medical Center/Disney Family Cancer Center
 (6.4 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +358 other locations
NA-831 Atazanavir and Dexamethasone Combination Therapy for the Treatment of COVID-19 Infection

This Phase 2/3 trial evaluates four treatment strategies for non-critically ill hospitalized participants (not requiring ICU admission and/or mechanical ventilation) with SARS CoV-2 infection, in which participants will receive NA-831 or Atazanavir with or without Dexamethasone.

complete blood count
cervical cap
electrocardiogram
mechanical ventilation
acute respiratory syndrome (sars)
Coronavirus Research Institute- Testing Site
 (5.4 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +29 other locations
Fitusiran Prophylaxis in Male Pediatric Subjects Aged 1 to Less Than 12 Years With Hemophilia A or B

Primary Objective: To confirm appropriate dose levels of fitusiran when administered to male pediatric participants (ages 1 to <12 years of age) with severe hemophilia A or B Secondary Objective: To characterize the safety and tolerability To characterize the pharmacokinetics (PK)

haemophilia a
bethesda assay
antihemophilic factor
factor ix
severe haemophilia a
Investigational Site Number 8400002
 (6.0 away) Contact site
  • 0 views
  • 04 Dec, 2020
  • +10 other locations
An Open-label Ascending Repeated Dose-finding Study of Sarilumab in Children and Adolescents With Polyarticular-course Juvenile Idiopathic Arthritis (pcJIA)

Primary Objective: To describe the pharmacokinetic (PK) profile of sarilumab in patients aged 2-17 years with Polyarticular-course Juvenile Idiopathic Arthritis (pcJIA) in order to identify the dose and regimen for adequate treatment of this population Secondary Objective: To describe the pharmacodynamic (PD) profile, the efficacy and the long-term safety of …

antirheumatic
arthritis
DMARD
rheumatoid factor
disease modifying antirheumatic drugs
Investigational Site Number 8400416
 (9.2 away) Contact site
  • 0 views
  • 04 Dec, 2020
  • +32 other locations