La Puente, California Clinical Trials

A listing of La Puente, California clinical trials actively recruiting patient volunteers.

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Found 53 clinical trials
Study of AMG 509 in Subjects With Metastatic Castration-Resistant Prostate Cancer

Evaluate the safety and tolerability of AMG 509 in adult subjects and determine the maximum tolerated dose (MTD) or recommended phase 2 dose (RP2D).

ejection fraction
gonadorelin
growth factor
gonadotrophin
dexamethasone
Research Site
 (9.5 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +3 other locations
P-PSMA-101 CAR-T Cells in the Treatment of Subjects With Metastatic Castration-Resistant Prostate Cancer (mCRPC)

An open-label, multi-center, single and cyclic ascending dose study of P-PSMA-101 autologous CAR-T cells in patients with mCRPC.

measurable disease
cancer
metastasis
metastatic cancer
metastatic disease
City of Hope Comprehensive Cancer Center
 (9.5 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +2 other locations
Total Marrow and Lymphoid Irradiation as Conditioning Regimen Before Hematopoietic Cell Transplantation in Patients With Myelodysplastic Syndrome or Acute Leukemia

This phase II trial studies how well total marrow and lymphoid irradiation works as a conditioning regimen before hematopoietic cell transplantation in patients with myelodysplastic syndrome or acute leukemia. Total body irradiation can lower the relapse rate but has some fatal side effects such as irreversible damage to normal internal …

granulocyte colony stimulating factor
ejection fraction
diffusion capacity of the lung for carbon monoxide
serum pregnancy test
syphilis
City of Hope Medical Center
 (9.5 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location
A Safety Study of Oral Venetoclax in Combination With Intravenous Pembrolizumab in Adult Participants With Previously Untreated Non-Small Cell Lung Cancer (NSCLC) With High Programmed Cell Death Ligand-1 (PD-L1) Expression

Non-Small Cell Lung Cancer (NSCLC) is a solid tumor, a disease in which cancer cells form in the tissues of the lung. It is the most common form of lung cancer, accounting for around 85% of lung cancers. The purpose of this study is to evaluate the safety and efficacy …

pd-l1
stage iv non-small cell lung cancer
lymphoma
growth factor
EGFR
Icri /Id# 217071
 (5.8 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +38 other locations
Tipifarnib for the Treatment of Advanced Solid Tumors Lymphoma or Histiocytic Disorders With HRAS Gene Alterations a Pediatric MATCH Treatment Trial

This phase II pediatric MATCH trial studies how well tipifarnib works in treating patients with solid tumors that have spread to other places in the body (advanced), lymphoma, or histiocytic disorders that have HRAS genetic alterations. Tipifarnib may block the growth of cancer cells that have specific genetic changes in …

bone marrow infiltration
pleural effusions
radiopharmaceutical therapy
pegfilgrastim
nervous system disorders
City of Hope Comprehensive Cancer Center
 (9.5 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +82 other locations
Phase 2 Trial of Voyager V1 in Combination With Cemiplimab in Cancer Patients

This is a Phase 2 study designed to determine the preliminary anti-tumor activity and confirm the safety of VV1 in combination with cemiplimab. The study will concurrently enroll patients with four distinct advanced malignancies in 5 separate tumor cohorts. The four cancers type are NSCLC and melanoma that are progressing …

stage iv non-small cell lung cancer
hepatitis b antigen
systemic therapy
ipilimumab
cemiplimab
City of Hope Medical Center
 (9.5 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +8 other locations
A Study to Evaluate the Safety Pharmacokinetics and Activity of GDC-6036 in Patients With Advanced or Metastatic Solid Tumors With a KRAS G12C Mutation

This is a Phase I dose-escalation and dose-expansion study that will evaluate the safety, pharmacokinetics (PK), and preliminary activity of GDC-6036 in patients with advanced or metastatic solid tumors with a KRAS G12C mutation.

solid tumour
solid tumor
kras g12c mutation
kras
ki-ras
City of Hope Comprehensive Cancer Center
 (9.5 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +7 other locations
A Safety and Efficacy Study Evaluating CTX130 in Subjects With Relapsed or Refractory Renal Cell Carcinoma

This is a single-arm, open-label, multicenter, Phase 1 study evaluating the safety and efficacy of CTX130 in subjects with relapsed or refractory renal cell carcinoma.

karnofsky performance status
carcinoma
renal cell carcinoma
Research Site 2
 (9.5 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +1 other locations
A Phase 3 Safety and Efficacy Study of Intravitreal Administration of Zimura (Complement C5 Inhibitor)

The objectives of this study are to evaluate the safety and efficacy of Zimura intravitreal administration in patients with geographic atrophy secondary to age-related macular degeneration (AMD)

maculopathy
geographic atrophy
macular degeneration
atrophy
complement c5
Retina Consultants of Orange County
 (8.1 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +22 other locations
Self-Management Survivorship Care in Stage I-III Non-small Cell Lung Cancer or Colorectal Cancer

This phase III trial studies how well a telehealth self-management program works in improving survivorship care and outcomes in stage I-III non-small cell lung cancer or colorectal cancer survivors. Survivor self-management program focuses on coaching patients on follow-up care after cancer treatments. Participating in the program may improve knowledge and …

stage ia3 lung cancer ajcc v8
stage iiib colorectal cancer ajcc v8
carcinoma
stage ia1 lung cancer ajcc v8
stage iii lung cancer ajcc v8
City of Hope Medical Center
 (9.5 away) Contact site
  • 4 views
  • 16 Feb, 2024
  • 1 location