Hollywood, California Clinical Trials

A listing of Hollywood, California clinical trials actively recruiting patient volunteers.

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Found 83 clinical trials
Study of a Novel Multicomponent Meningococcal Group B Vaccine When Given Alone or With Other Licensed Vaccines in Adults, Adolescents, Toddlers and Infants

Primary Objective:To describe the safety profile of the SP MenB vaccine formulations and the 2 licensed MenB comparator vaccines in healthy adults, adolescents, toddlers and infants, when administered alone (Stages 1-4) or concomitantly with MenQuadfiTM (MenACYW conjugate vaccine) (for Stages 2-4 only), and with age-appropriated routine pediatric vaccines (for Stages …

TOI Clinical Research LLC_ Whittier_Investigational Site Number: 8400006
 (1.7 away) Contact site
  • 0 views
  • 06 May, 2024
  • +5 other locations
A Study of CAD106 and CNP520 Versus Placebo in Participants at Risk for the Onset of Clinical Symptoms of Alzheimer's Disease

The purpose of this study is to test whether two investigational drugs called CAD106 and CNP520, administered separately, can slow down the onset and progression of clinical symptoms associated with Alzheimer's disease (AD) in participants at the risk to develop clinical symptoms based on their age and genotype.

mini-mental state examination
apolipoprotein e4
alzheimer's disease
mental state examination
University of Southern California Keck School of Medicine Alzheimer Disease Research Center
 (7.3 away) Contact site
  • 32 views
  • 16 Feb, 2024
  • +126 other locations
Enfortumab Vedotin and Pembrolizumab With or Without Chemotherapy vs. Chemotherapy Alone in Untreated Locally Advanced or Metastatic Urothelial Cancer

This study is being done to see how well two drugs (enfortumab vedotin and pembrolizumab) work together alone or with platinum chemotherapy to treat patients with urothelial cancer. The study will compare these drugs to other drugs that are usually used to treat this cancer (standard of care). The patients …

measurable disease
transitional cell carcinoma
cancer
metastatic urothelial carcinoma
external beam radiation therapy
Providence St. Joseph Medical Center
 (9.3 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +25 other locations
A Study to Evaluate the Efficacy and Safety of JCAR017 in Adult Subjects With Relapsed or Refractory Indolent B-cell Non-Hodgkin Lymphoma (NHL)

This is a global Phase 2, open-label, single-arm, multicohort, multicenter study to evaluate efficacy and safety of JCAR017 in adult subjects with r/r FL or MZL. The study will be conducted in compliance with the International Council on Harmonisation (ICH) of Technical Requirements for Registration of Pharmaceuticals for Human Use/Good …

b-cell lymphoma
hodgkin's disease
fludarabine
follicular lymphoma
systemic therapy
UCLA Medical Centre-Santa Monica
 (9.3 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +35 other locations
Outcome Study Assessing a 75 Milligrams (mg) Dose of Macitentan in Patients With Pulmonary Arterial Hypertension

The purpose of this study is to demonstrate superiority of macitentan 75 milligrams (mg) in prolonging the time to the first clinical events committee (CEC)-adjudicated morbidity or mortality (M/M) event in participants with symptomatic pulmonary arterial hypertension (PAH) compared to macitentan 10 mg.

ventricular septal defects
HIV Infection
patent ductus arteriosus
heart disease
ventricular septal defect
USC Keck
 (7.3 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +210 other locations
A Medical Research Study Designed to Determine if Venglustat Can be a Future Treatment for ADPKD Patients

Primary Objective: To determine the effect of venglustat on the rate of total kidney volume (TKV) growth (Stage and estimated glomerular filtration rate (eGFR) decline in patients at risk of rapidly progressive Autosomal Dominant Polycystic Kidney Disease (ADPKD) (Stage 2). Secondary Objectives: To determine the effect of venglustat on the …

ophthalmological examination
urine osmolality
glomerular filtration rate
tolvaptan
cyst
Investigational Site Number 8400017
 (6.5 away) Contact site
  • 0 views
  • 04 Dec, 2020
  • +80 other locations
Phase 2 Study of SAR439859 Versus Physician's Choice in Locally Advanced or Metastatic ER-positive Breast Cancer (AMEERA-3)

Primary Objective: To determine whether SAR439859 per os improves progression free survival (PFS) when compared with a endocrine monotherapy of the choice of the physician, in participants with metastatic or locally advanced breast cancer. Secondary Objectives: To compare the overall survival in the 2 treatment arms To assess the objective …

advanced breast cancer
stage iv breast cancer
locally advanced breast cancer
breast cancer
exemestane
Investigational Site Number 8400024
 (9.3 away) Contact site
  • 0 views
  • 04 Dec, 2020
  • +125 other locations
A Study to Evaluate the Efficacy and Safety of Intravenous Prasinezumab in Participants With Early Parkinson's Disease  

This is a multicenter, randomized, double-blind, placebo-controlled study that will evaluate the efficacy and safety of intravenous (IV) prasinezumab versus placebo in participants with Early Parkinson's Disease (PD) who are on stable symptomatic PD medication.

bradykinesia
tremor
dopamine transporter
parkinsonism
early parkinson's
Cedars Sinai Medical Center
 (2.8 away)
  • 0 views
  • 28 Jun, 2022
  • +125 other locations
A Study Evaluating the Efficacy and Safety of Adjuvant Atezolizumab or Placebo and Trastuzumab Emtansine for Participants With HER2-Positive Breast Cancer at High Risk of Recurrence Following Preoperative Therapy

This is a Phase III, two-arm, randomized, double-blind placebo-controlled study in participants with HER2-positive primary breast cancer who have received preoperative chemotherapy and HER2-directed therapy, including trastuzumab followed by surgery, with a finding of residual invasive disease in the breast and/or axillary lymph nodes.

Roy and Patricia Disney Family Cancer Center- Providence Saint Joseph Medical Center
 (4.8 away) Contact site
  • 0 views
  • 05 Oct, 2021
  • +301 other locations
A Study of Tucatinib vs. Placebo in Combination With Ado-trastuzumab Emtansine (T-DM1) for Patients With Advanced or Metastatic HER2+ Breast Cancer

This study is being done to see if tucatinib with ado-trastuzumab emtansine (T-DM1) works better than T-DM1 alone to help patients who have a specific type of breast cancer called HER2 positive breast carcinoma. The breast cancer in this study is either metastatic (spread into other parts of the body) …

UCLA Medical Center / David Geffen School of Medicine
 (9.3 away) Contact site
  • 0 views
  • 14 Mar, 2022
  • +227 other locations