Garden Grove, California Clinical Trials

A listing of Garden Grove, California clinical trials actively recruiting patient volunteers.

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Found 55 clinical trials
A Study of Tirzepatide (LY3298176) Compared With Dulaglutide on Major Cardiovascular Events in Participants With Type 2 Diabetes

The purpose of the trial is to assess the efficacy and safety of tirzepatide to dulaglutide in participants with type 2 diabetes and increased cardiovascular risk.

tirzepatide
body mass index
dulaglutide
cardiovascular disease
Diabetes Associates Medical Group
 (3.7 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +650 other locations
A Study of Donanemab (LY3002813) in Participants With Early Alzheimer's Disease (TRAILBLAZER-ALZ 2)

The reason for this study is to see how safe and effective the study drug donanemab is in participants with early Alzheimer's disease.

flortaucipir
mini-mental state examination
florbetapir
alzheimer's disease
positron emission tomography
Irvine Clinical Research Center
 (8.6 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +85 other locations
NA-831 Atazanavir and Dexamethasone Combination Therapy for the Treatment of COVID-19 Infection

This Phase 2/3 trial evaluates four treatment strategies for non-critically ill hospitalized participants (not requiring ICU admission and/or mechanical ventilation) with SARS CoV-2 infection, in which participants will receive NA-831 or Atazanavir with or without Dexamethasone.

combination therapy
mechanical ventilation
critical illness
electrocardiogram (ecg)
dexamethasone
Coronavirus Research Institute
 (3.7 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +29 other locations
A Study of Lasmiditan (LY573144) Treatment in Children Aged 6 to 17 With Migraine

The reason for this study is to see if lasmiditan is safe and effective in children aged 6 to 17 with migraine. The study will last up to 20 weeks and may include up to 4 visits.

lasmiditan
preventive medication
migraine
ly573144
treatment regimen
Core Healthcare Group
 (9.7 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +162 other locations
Fitusiran Prophylaxis in Male Pediatric Subjects Aged 1 to Less Than 12 Years With Hemophilia A or B

Primary Objective: To confirm appropriate dose levels of fitusiran when administered to male pediatric participants (ages 1 to <12 years of age) with severe hemophilia A or B Secondary Objective: To characterize the safety and tolerability To characterize the pharmacokinetics (PK)

hemophilia
severe haemophilia a
fitusiran
bethesda assay
haemophilia a
Investigational Site Number 8400010
 (3.7 away) Contact site
  • 0 views
  • 04 Dec, 2020
  • +10 other locations
Long-term Safety and Efficacy Study of Fitusiran in Patients With Hemophilia A or B With or Without Inhibitory Antibodies to Factor VIII or IX

Primary Objective: To characterize the long-term safety and tolerability of fitusiran Secondary Objectives: To characterize the long-term efficacy of fitusiran as assessed by the frequency of: Bleeding episodes Spontaneous bleeding episodes Target joint bleeding episodes To characterize the effects of fitusiran on health-related quality of life (HRQOL) measures in participants …

hemophilia
severe haemophilia a
fitusiran
hemarthrosis
haemophilia a
Investigational Site Number 8400016
 (3.7 away) Contact site
  • 0 views
  • 04 Dec, 2020
  • +40 other locations
Fitusiran Prophylaxis in Male Pediatric Subjects Aged 1 to Less Than 12 Years With Hemophilia A or B

Primary Objective: To confirm appropriate dose levels of fitusiran when administered to male pediatric participants (ages 1 to <12 years of age) with severe hemophilia A or B Secondary Objective: To characterize the safety and tolerability To characterize the pharmacokinetics (PK)

hemophilia
severe haemophilia a
fitusiran
bethesda assay
haemophilia a
Investigational Site Number 8400010
 (3.7 away) Contact site
  • 0 views
  • 04 Dec, 2020
  • +5 other locations
test v6.10  

test

Orange County Research Center
 (7.6 away)
  • 0 views
  • 02 Aug, 2023
  • +1 other locations
None

Center for Inherited Blood Disorders (CIBD)-Site Number:8400001
 (3.7 away) Contact site
  • 0 views
  • 26 Sep, 2023
  • +2 other locations
A Phase 3 Safety and Efficacy Study of Intravitreal Administration of Zimura (Complement C5 Inhibitor)

The objectives of this study are to evaluate the safety and efficacy of Zimura intravitreal administration in patients with geographic atrophy secondary to age-related macular degeneration (AMD)

complement c5
atrophy
age-related macular degeneration
macular degeneration
geographic atrophy
Retina Consultants of Orange County
 (8.9 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +22 other locations