Weston, Canada Clinical Trials

A listing of Weston, Canada clinical trials actively recruiting patients volunteers.

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Found 69 clinical trials
Novel MRI-Guided Ultrasound Stimulated Microbubble Radiation Treatment for Patients With Chest-wall and Locally-Advanced Breast Cancer

The objective of this study is to demonstrate the feasibility of novel MRI-guided ultrasound stimulated microbubble treatment to enhance radiation effects in humans receiving external beam radiotherapy delivered using a LINAC (linear accelerator) radiation therapy device.

advanced breast cancer
carcinoma
potassium
breast cancer staging
Sunnybrook Health Sciences Centre
 (7.0 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location
First in Human Study of M6223 in Participants With Metastatic or Locally Advanced Solid Unresectable Tumors

The main purpose of this study is to determine the safety, tolerability, pharmacokinetics (PK), immunogenicity and (if observed) the maximum tolerated dose (MTD) of M6223 as a single agent (Part 1A) and of M6223 combined with bintrafusp alfa (Part 1B) in participants with metastatic or locally advanced solid unresectable tumors.

Princess Margaret Cancer Centre
 (7.3 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +3 other locations
A Study of Tirzepatide (LY3298176) Compared With Dulaglutide on Major Cardiovascular Events in Participants With Type 2 Diabetes

The purpose of the trial is to assess the efficacy and safety of tirzepatide to dulaglutide in participants with type 2 diabetes and increased cardiovascular risk.

cardiovascular disease
dulaglutide
tirzepatide
body mass index
LMC Endocrinology Centres Ltd.
 (2.2 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +650 other locations
Durvalumab With or Without Olaparib as Maintenance Therapy After First-Line Treatment of Advanced and Recurrent Endometrial Cancer

A study to assess the efficacy and safety of durvalumab in combination with platinum-based chemotherapy (paclitaxel + carboplatin) followed by maintenance durvalumab with or without olaparib for patients with newly diagnosed advanced or recurrent endometrial cancer.

cancer therapy
endometrial cancer
paclitaxel
carboplatin
carboplatin paclitaxel
Research Site
 (6.8 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +94 other locations
Cognitive Outcomes After Dexmedetomidine Sedation in Cardiac Surgery Patients

Anesthesia is a drug induced, reversible, comatose state that facilitates surgery and it is widely assumed that cognition returns to baseline after anesthetics have been eliminated. However, many patients have persistent memory impairment for weeks to months after surgery. Cardiac surgery appears to carry the highest risk of postoperative cognitive …

cognitive impairment
coronary artery bypass graft
cabg
cardiac surgery
heart surgery
Sunnybrook Health Sciences Centre
 (7.0 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location
A Study of Donanemab (LY3002813) in Participants With Early Alzheimer's Disease (TRAILBLAZER-ALZ 2)

The reason for this study is to see how safe and effective the study drug donanemab is in participants with early Alzheimer's disease.

florbetapir
mini-mental state examination
flortaucipir
positron emission tomography
alzheimer's disease
Toronto Memory Program
 (9.0 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +85 other locations
A Phase 3 Study to Evaluate Efficacy and Safety of AL001 in Frontotemporal Dementia (INFRONT-3)

A phase 3 double blind, placebo controlled study evaluating the efficacy and safety of AL001 in participants at risk for or with frontotemporal dementia due to heterozygous mutations in the progranulin gene.

aphasia
progranulin
dementia
pick's disease
Sunnybrook Research Institute - University of Toronto
 (7.3 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +46 other locations
A Study of Lasmiditan (LY573144) Treatment in Children Aged 6 to 17 With Migraine

The reason for this study is to see if lasmiditan is safe and effective in children aged 6 to 17 with migraine. The study will last up to 20 weeks and may include up to 4 visits.

headache
ly573144
migraine
lasmiditan
treatment regimen
Women's College Hospital
 (6.9 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +162 other locations
Intergenerational Program for Social Isolation and Loneliness in Older Adults Discharged From the Emergency Department (SIL)

Social isolation and loneliness worsens older adults' risk of dementia, quality of life, and death as much as smoking. Older adults are more likely to use emergency services and are also more likely to experience social isolation and loneliness than younger people. The emergency department is a new setting to …

Accepts healthy volunteers
Mount Sinai Hospital
 (7.0 away) Contact site
  • 0 views
  • 23 Aug, 2023
  • 1 location
Treatment of Moderate to Severe Lateral Canthal Lines and Glabellar Lines Alone or in Combination

This study is designed to evaluate the safety and efficacy of a single dose of QM1114-DP for the treatment of moderate to severe LCL and moderate to severe GL, alone or in combination.

Bertucci Medspa, Inc
 (7.4 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +9 other locations