Scarborough, Canada Clinical Trials

A listing of Scarborough, Canada clinical trials actively recruiting patients volunteers.

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Found 41 clinical trials
A Study to Evaluate the Efficacy and Safety of Intravenous Prasinezumab in Participants With Early Parkinson's Disease  

This is a multicenter, randomized, double-blind, placebo-controlled study that will evaluate the efficacy and safety of intravenous (IV) prasinezumab versus placebo in participants with Early Parkinson's Disease (PD) who are on stable symptomatic PD medication.

resting tremor
early parkinson's
parkinsonism
dopamine transporter
tremor
Toronto Memory Program
 (6.2 away)
  • 0 views
  • 28 Jun, 2022
  • +125 other locations
Precision Orthodontics: A Comparison of Custom vs Traditional Bracket Treatment Efficiency

This investigational testing aims to target multiple investigations sites to examine treatment efficiency metrics using a completely digital and patient-specific bracket treatment system for the correction of malocclusions.

eruption
Orthodontics at Don Mills
 (4.7 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +2 other locations
Novel MRI-Guided Ultrasound Stimulated Microbubble Radiation Treatment for Patients With Chest-wall and Locally-Advanced Breast Cancer

The objective of this study is to demonstrate the feasibility of novel MRI-guided ultrasound stimulated microbubble treatment to enhance radiation effects in humans receiving external beam radiotherapy delivered using a LINAC (linear accelerator) radiation therapy device.

breast cancer staging
advanced breast cancer
carcinoma
potassium
Sunnybrook Health Sciences Centre
 (8.1 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location
A Study of Tirzepatide (LY3298176) Compared With Dulaglutide on Major Cardiovascular Events in Participants With Type 2 Diabetes

The purpose of the trial is to assess the efficacy and safety of tirzepatide to dulaglutide in participants with type 2 diabetes and increased cardiovascular risk.

dulaglutide
body mass index
tirzepatide
cardiovascular disease
LMC Endocrinology Centres Ltd.
 (8.3 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +650 other locations
Cognitive Outcomes After Dexmedetomidine Sedation in Cardiac Surgery Patients

Anesthesia is a drug induced, reversible, comatose state that facilitates surgery and it is widely assumed that cognition returns to baseline after anesthetics have been eliminated. However, many patients have persistent memory impairment for weeks to months after surgery. Cardiac surgery appears to carry the highest risk of postoperative cognitive …

cognitive impairment
anesthesia
dexmedetomidine
sternotomy
anesthetics
Sunnybrook Health Sciences Centre
 (8.1 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location
A Study of Donanemab (LY3002813) in Participants With Early Alzheimer's Disease (TRAILBLAZER-ALZ 2)

The reason for this study is to see how safe and effective the study drug donanemab is in participants with early Alzheimer's disease.

positron emission tomography
florbetapir
alzheimer's disease
flortaucipir
mini-mental state examination
Toronto Memory Program
 (6.2 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +85 other locations
5 Fractions of Pelvic SABR With Intra Prostatic SABR Boost:

Stereotactic Ablative Body Radiotherapy (SABR) given in 5 weekly fractions. Simultaneously treating the pelvic lymph nodes, prostate and MRI-nodule to a total dose of 25 Gy, 35 Gy and up to 50 Gy, respectively. The radiation will be given with 6-18 months of ADT. 5-fraction SABR is a feasible, well-tolerated, …

adenocarcinoma of prostate
adenocarcinoma
stereotactic body radiation therapy
Sunnybrook Health Sciences Center
 (8.1 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location
Does Physiotherapy Plus Non-invasive Brain Stimulation Improve Motor Recovery in Children With Acquired Brain Injury?

The current study will evaluate the feasibility of transcranial direct current stimulation (tDCS) combined with an existing intensive physiotherapy program for children with ABI within the in/day-patient brain injury program at Holland Bloorview Kids Rehabilitation Hospital, Toronto, Canada. This feasibility randomized control trial will allocate 30 participants with ABI (age …

perinatal brain injury
electrical stimulation
stroke
transcranial direct current stimulation
brain stimulation
Holland Bloorview Kids Rehabilitation Hospital
 (8.1 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location
Pilot Study to Evaluate Photoacoustic Imaging in Head and Neck Cancer

In this study, PA imaging will be used to examine the physiological and physical changes in lymph node involvements of head and neck cancer during radiotherapy with or without chemotherapy. Our objective in this pilot study will be to evaluate if PA parameters change within the lymph node involvements during …

chemoradiation therapy
renal function test
photoacoustic imaging
chemoradiotherapy
head and neck carcinoma
Sunnybrook Health Sciences Centre
 (8.1 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location
Pilot Study to Evaluate Photoacoustic Imaging for Characterizing Breast Masses and Breast Tumor Response to Neoadjuvant Chemotherapy Pilot Study to Evaluate Photoacoustic Imaging for Characterizing Breast Masses and Breast Tumor Response to Neoadjuvant Chemotherapy

Our objective in this pilot study will be to identify PA parameters that can distinguish benign vs. malignant lesions, and also, if PA parameters change with within breast tumors during chemotherapy treatment over time.

locally advanced breast cancer
advanced breast cancer
HER2
breast mass
breast neoplasm
Sunnybrook Health Sciences Centre
 (8.1 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location