Etobicoke, Canada Clinical Trials

A listing of Etobicoke, Canada clinical trials actively recruiting patients volunteers.

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Found 66 clinical trials
A Study to Evaluate the Safety Pharmacokinetics and Activity of GDC-6036 in Patients With Advanced or Metastatic Solid Tumors With a KRAS G12C Mutation

This is a Phase I dose-escalation and dose-expansion study that will evaluate the safety, pharmacokinetics (PK), and preliminary activity of GDC-6036 in patients with advanced or metastatic solid tumors with a KRAS G12C mutation.

ki-ras
kras g12c mutation
solid tumor
solid tumour
kras
Princess Margaret Cancer Centre
 (6.6 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +7 other locations
Does Physiotherapy Plus Non-invasive Brain Stimulation Improve Motor Recovery in Children With Acquired Brain Injury?

The current study will evaluate the feasibility of transcranial direct current stimulation (tDCS) combined with an existing intensive physiotherapy program for children with ABI within the in/day-patient brain injury program at Holland Bloorview Kids Rehabilitation Hospital, Toronto, Canada. This feasibility randomized control trial will allocate 30 participants with ABI (age …

brain stimulation
perinatal brain injury
stroke
transcranial direct current stimulation
discomfort
Holland Bloorview Kids Rehabilitation Hospital
 (9.7 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location
Accelerated iTBS for Depressed Patients During the COVID-19 Pandemic

The current study aims to assess the feasibility, acceptance and clinical outcomes of a practical high-dose aiTBS protocol, including tapering treatments and symptom-based relapse prevention treatments, in patients with unipolar depression previously responsive to ECT and patients needing urgent treatment due to symptom severity during the COVID-19 pandemic.

depressive episode
major depressive disorder
depression
psychosis
relapse prevention
CAMH
 (5.0 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location
Invasive Coronary Angiography Early in Ischemic Heart Failure

To compare the outcomes of patients with acute heart failure who undergo early coronary angiography vs. usual care

heart disease
angina
troponin
heart failure
angina pectoris
University Health Network
 (6.9 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location
PPMI 2.0 Clinical -Establishing a Deeply Phenotyped PD Cohort

The Parkinson Progression Marker Initiative 2.0 (PPMI 2.0) is a longitudinal, observational, multi-center natural history study to assess progression of clinical features, digital outcomes, and imaging, biologic and genetic markers of Parkinson's disease (PD) progression in study participants with manifest PD, prodromal PD, and healthy controls The overall goal of …

modafinil
genetic testing
muscle rigidity
datscan
tremor
Toronto Western Hospital
 (5.8 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +45 other locations
Molecular Characteristics of Gastroesophageal Adenocarcinoma (MOCHA): A Prospective Feasibility Study

Researchers are looking to further our knowledge on disease biology and treatment selection for gastroesophageal adenocarcinoma. The purpose of this study is to see how useful it is to look for changes and characteristics in your genes (molecules that contain instructions for the development and functioning of the cells) and …

University Health Network
 (6.9 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location
Thrombo-Elastography Guided Management of ECMO

Anticoagulation and coagulation management during ECMO is a challenge. Bleeding and clotting are major sources of morbidity and mortality. The currently used strategies are of poor evidence. This observational study wants to evaluate the use of automated thromboelastography (TEG 6s) to guide the management of coagulation and anticoagulation in patients …

coagulopathy
hemorrhage
thromboelastography
RET
University Health Network
 (6.7 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location
Pilot Study to Evaluate Photoacoustic Imaging in Head and Neck Cancer

In this study, PA imaging will be used to examine the physiological and physical changes in lymph node involvements of head and neck cancer during radiotherapy with or without chemotherapy. Our objective in this pilot study will be to evaluate if PA parameters change within the lymph node involvements during …

cancer
neutrophil count
neck cancer
head and neck cancer
head and neck carcinoma
Sunnybrook Health Sciences Centre
 (9.7 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location
Pilot Study to Evaluate Photoacoustic Imaging for Characterizing Breast Masses and Breast Tumor Response to Neoadjuvant Chemotherapy Pilot Study to Evaluate Photoacoustic Imaging for Characterizing Breast Masses and Breast Tumor Response to Neoadjuvant Chemotherapy

Our objective in this pilot study will be to identify PA parameters that can distinguish benign vs. malignant lesions, and also, if PA parameters change with within breast tumors during chemotherapy treatment over time.

advanced breast cancer
breast mass
breast neoplasm
locally advanced breast cancer
HER2
Sunnybrook Health Sciences Centre
 (9.7 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location
Cell-free DNA in Hereditary And High-Risk Malignancies

The goal of this study is to develop an effective, sensitive blood test that can detect early tumours in patients with known or suspected hereditary cancer syndromes (HCS). If this new blood test is accurate, it could be used to screen patients for cancer and allow for earlier cancer detection. …

cancer
cell-free dna
hereditary cancer syndromes
hereditary cancer
blood test
Sinai Health System
 (6.6 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +6 other locations