Eye Disease Clinical Trials

A listing of Eye Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 295 clinical trials
Assessing Dextenza Insert After SMILE Procedure

This three-month prospective, open-label, single-center, randomized investigator initiated clinical study seeks to investigate the efficacy of DEXTENZA when placed in the lower canaliculus (study eye) compared to topical corticosteroids (control eye) following bilateral SMILE surgery. In addition, the study will evaluate physician assessment of ease of DEXTENZA insertion

  • 0 views
  • 05 Aug, 2020
Oral Oxytocin's Effects on Attention Control

The main aim of the study is to investigate whether orally administered oxytocin (24IU) could modulate attention control using a social-emotional saccade/antisaccade eye-tracking paradigm.

  • 0 views
  • 16 Feb, 2024
  • 1 location
The RESTORE Study A Randomized Controlled Masked (Reading Center) Prospective Study

To determine patient preference and treatment outcomes with an intracanalicular dexamethasone (0.4mg) insert compared to standard steroid drop regimen in the contralateral eye following bilateral PRK surgery.

  • 0 views
  • 16 Feb, 2024
  • 1 location
Topotecan Episcleral Plaque for Treatment of Retinoblastoma

This single site, single-arm, non-randomized, dose escalation phase I toxicity clinical trial will assess primarily the safety and secondarily the efficacy of episcleral topotecan in patients with active residual or recurrent intraocular retinoblastoma in at least one eye following completion of first-line therapy.

intraocular retinoblastoma
brachytherapy
renal function
platelet count
topotecan
  • 0 views
  • 05 Aug, 2020
PHP and Immunotherapy in Metastasized UM

Melanoma of the eye (ocular/uveal melanoma) is an uncommon type of cancer that is associated with a high mortality. It usually disseminates rapidly throughout the body, most commonly to the liver and lungs.

  • 0 views
  • 16 Feb, 2024
  • 1 location
Responses to E-Cigarette Advertising

During exposure, they will be assessed for real-time visual attention using eye-tracking, orienting responses using heart rate, and arousal using skin conductance as well as pre- and post-ad self-report measures of attitudes, susceptibility, and behavioral intentions.

  • 0 views
  • 16 Feb, 2024
  • 1 location
Baseline Relative Peripheral Refraction in Myopia Control

This study includes 5 visits: Visit 1: baseline, Visit 2: lens dispensing, Visit 3: 2-week follow-up, Visit 4: 6-month follow-up, and Visit 5: 12-month follow-up. All eye examinations will be carried out in the Optometry Research Centre (A137), the School of Optometry, the Hong Kong Polytechnic University.

Accepts healthy volunteers
  • 0 views
  • 08 Dec, 2023
  • 1 location
Assessing the Efficacy and Safety of DEXTENZA in Pseudo Phakic Patients Undergoing Gas Bubble Repair and Laser Following Retinal Detachment

This prospective, open-label, single-center, randomized, investigator-sponsored clinical study seeks to investigate: how will pseudophakic patients respond in terms of objective and subjective outcomes, when treated with Dextenza compared to topical prednisolone acetate following gas bubble repair and laser for RD.

detachment
retinal detachment
laser surgery
topical prednisolone
  • 0 views
  • 16 Feb, 2024
  • 1 location
Topical Application of Imiquimod Gel at Different Concentrations in Actinic Cheilitis

Actinic cheilitis is a potentially malignant lesion on the lower lip, which can progress to more serious illnesses such as cancer if not treated. Usually treatment of this condition is only based on clinical appearance, but there is no established cure treatment. Topical imiquimod is a medicine indicated for the …

  • 0 views
  • 16 Feb, 2024
  • 2 locations
Combined Laser-surgical Technology of RRD Treatment

Purpose: to assess the efficacy and safety of combined laser-surgical technology of RRD treatment

  • 0 views
  • 05 Aug, 2020