Inflammation Clinical Trials

A listing of Inflammation medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 602 clinical trials
Change of NLRP3 Inflammasome Expression Level Symptoms and Functional Status in HFpEF Patients Treated With ARNI

Underlying inflammation has been increasingly recognized in heart failure with a preserved ejection fraction(HFpEF). But there is no study reported the relationship between NLRP3 inflammasome and HFpEF.

valsartan
diastolic dysfunction
ntprobnp
sacubitril
heart disease
  • 0 views
  • 16 Feb, 2024
  • 1 location
Microbiota in COVID-19 Patients for Future Therapeutic and Preventive Approaches

On progression of the disease, bacterial superinfection facilitated by inflammation and virus related damage, has been identified as the main factor for patient outcome, but the role of the host versus the environment microbiome remains unclear.

critically ill
acute respiratory distress
pneumonia
respiratory distress
SARS
  • 0 views
  • 16 Feb, 2024
  • 1 location
Evaluation of Eosinophil Phenotype in COPD Patients

By multicolor flow cytometry the investigators will analyze membrane molecules and intracellular cytokines associated to chemotaxis, degranulation and inflammation. The study will enroll 30 patients (15 stable and 15 with exacerbation). Results will be analyzed taking into account clinical status,disease progression and response to treatment.

flow cytometry
eosinophils
lung disorder
chemotactic factors
pulmonary disease
  • 0 views
  • 16 Feb, 2024
  • 1 location
Cellular Immunity, Neuroendocrine, and Inflammatory Factors for Clinical Prognosis in Acute Coronary Syndrome

In acute coronary syndrome (ACS), there is an increase in cortisol levels, as an expression of the stress response, and C-reactive protein, as an expression of the inflammatory response, which are in turn associated with changes in the components of cellular immunity, and ultimately are predictors of clinical events. The …

  • 0 views
  • 23 Jul, 2024
Postoperative Neurocognitive Disorders

The purpose of this study is to examine the mechanisms of brain injury contributing to postoperative neurocognitive disorders (PNCD) in an at-risk population (obstructive sleep apnea (OSA)) undergoing surgery. The investigators will enroll 50 OSA patients scheduled for surgery. All patients will have a brain scan (fMRI) within five days …

cognitive assessment
polysomnography
apnea-hypopnea index
robotic surgery
brain injury
  • 0 views
  • 16 Feb, 2024
  • 1 location
Effect of COVID-19 on Platelet Aggregation

This is a mechanistic, observational, prospective, case and control study, to compare platelet aggregation, analyzed by Multiplate-ADP, in hospitalized patients diagnosed with COVID-19 versus healthy controls. Thus will be included 50 patients who present with respiratory symptoms within 72 hours of hospitalization and confirmation of the diagnosis of COVID-19 by …

covid-19
respiratory symptom
platelet aggregation
acute respiratory syndrome (sars)
chronic disease
  • 0 views
  • 16 Feb, 2024
  • 1 location
Effect of Oxalate and Urate Metabolism on CKD Evolution

The current study primarily aimed to characterize the oxalate and uric acid metabolism in CKD patients and to analyze its association with renal survival prognosis. Secondarily, the study is planned to determine whether hyperoxalemia and hyperuricemia are independent risk factors for cardiovascular events and mortality.

chronic kidney disease
hyperuricemia
dialysis
oxalate
antibiotics
  • 0 views
  • 16 Feb, 2024
  • 1 location
Prospective Longitudinal Cohort Study of Vasculitis Patients

VASCO is a prospective observational cohort study which aim to describe the presentation, comorbidities, management, outcomes and damage of vasculitis patients, from the analysis of the clinical, biological and immunological data.

vasculitis
  • 0 views
  • 05 Aug, 2020
Microvascular Flow and Reactivity in Patients Presenting in the Acute Phase of COVID-19.

Considering that the intensity of systemic microvascular changes in patients in the acute phase of COVID-19 could be related to disease progression and prognosis, the present cross-sectional and observational study aims to investigate the presence of endothelial dysfunction in these patients, also looking for to evaluate associations between the presence …

covid-19
SARS
endothelial dysfunction
acute respiratory syndrome (sars)
  • 0 views
  • 16 Feb, 2024
  • 1 location
Longitudinal COVID-19 Cohort Study

The novel SARS-CoV-2 virus has quickly spread worldwide, with substantial morbidity and mortality. There is very limited understanding of the short- and longer-term inflammatory/immunological and clinical course. However, the investigators expect survivors from severe COVID-19 to experience persistent functional impairments, as demonstrated in prior studies of patients with acute respiratory …

acute respiratory syndrome (sars)
acute respiratory distress
respiratory distress
acute respiratory failure
SARS
  • 0 views
  • 05 Aug, 2020