Obesity Clinical Trials

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Transcranial Direct Current Stimulation for Impulsivity and Food-related Impulsivity in Obesity

In this study the investigators aim to assess whether transcranial direct current stimulation (tDCS; a safe non-invasive method for modulating the activity of specific brain regions) when applied over the orbitofrontal cortex (OFC) is able to modulate impulsivity in obese participants.

Evaluate the Safety Tolerability Pharmacokinetics and Pharmacodynamics of IBI362 in Overweight or Obesity Subjects

The aim of this trial is to investigate Safety, Tolerability, PK and PD for Multiple Doses of IBI362 in Male and Female Subjects being Overweight or with Obesity.

A Study to Test How Well Different Doses of BI 1356225 Are Tolerated by Men and Women Who Are Overweight or Obese.

The primary objective of this trial is to investigate safety and tolerability of BI 1356225 in male and female patients with overweight and obesity following oral administration of multiple rising doses per day over 28 days. Secondary objectives are the exploration of pharmacokinetics (PK) of BI 1356225 after multiple oral …

Effects of Almond Consumption on the Human Gastrointestinal Microbiota and Metabolic Health

The proposed work will investigate the effect of almond consumption as a snack on human gastrointestinal microbiota and on metabolic health.

Teaching Novel Values-Based Skills to Improve Long-Term Weight Loss

This NIDDK funded R01 project is a randomized controlled clinical trial to compare the efficacy of an intervention based on Acceptance and Commitment Therapy (ACT) and a Self-Regulation (SR) intervention on weight loss maintenance over a 30-month period. All participants will first complete a well-validated online weight loss intervention (months …