Multiple Sclerosis Clinical Trials

A listing of Multiple Sclerosis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 1346 clinical trials
A Study to Evaluate the Safety and Tolerability of Single and Multiple Ascending Doses of HPN-01 in Healthy Subjects

This study is a randomized, double-blind, placebo-controlled first-in-human study in which the safety, tolerability, pharmacokinetics and pharmacodynamics of orally administered HPN-01 will be evaluated in healthy subjects

  • 0 views
  • 05 Aug, 2020
Effects of NAD3 Supplementation on Biomarkers of Aging

This is a randomized, parallel-group, placebo-controlled, clinical trial in middle-aged and older male and female subjects from Ohio. Subjects will take an over-the-counter dietary supplement or a placebo for 12 weeks. Outcome measures will include body weight, systolic and diastolic blood pressure, standard blood chemistries (e.g. chemistry panel, lipid panel, …

body mass index
systolic blood pressure
fatigue
  • 0 views
  • 16 Feb, 2024
  • 1 location
A Trial to Evaluate Safety and Tolerability of TST001 in Advanced or Metastatic Solid Tumors

This is an open label Phase 1, First in Human trial of TST001, a recombinant humanized anti-Claudin 18.2 (CLDN18.2) IgG1 monoclonal antibody. It is being tested against advanced and/or metastatic solid tumors including gastric, gastroesophageal junction, pancreatic, colon and lung cancers.

ovarian cancer
monoclonal antibodies
measurable disease
cancer
pancreatic cancer
  • 0 views
  • 05 Aug, 2020
Diffusion MRI for Head and Neck Cancer

D(t) and K(t) of tumors can vary substantially depending on t in the range of diffusion times (30-100 ms) typically used in clinical scan.

  • 0 views
  • 25 Apr, 2025
Diffusion MRI for Head and Neck Cancer

D(t) and K(t) of tumors can vary substantially depending on t in the range of diffusion times (30-100 ms) typically used in clinical scan.

chemoradiation therapy
chemoradiotherapy
cancer
neck cancer
squamous cell carcinoma of head and neck
  • 0 views
  • 16 Feb, 2024
  • 1 location
Effects of Almond Consumption on the Human Gastrointestinal Microbiota and Metabolic Health

The proposed work will investigate the effect of almond consumption as a snack on human gastrointestinal microbiota and on metabolic health.

microbiota
  • 0 views
  • 16 Feb, 2024
  • 1 location
Evaluating Efficacy of the Dexmedetomidine Transdermal System for Postoperative Analgesia Following Abdominoplasty

The primary objective of this study is to evaluate the analgesic efficacy of Dexmedetomidine Transdermal System (DMTS), compared with placebo, in participants following abdominoplasty.

analgesia
analgesics
postoperative pain relief
dexmedetomidine
  • 0 views
  • 16 Feb, 2024
  • 4 locations
Clinical Trial for Surgery of the Ulnar Nerve (SUN) at the Elbow

This research is studying two surgical procedures in a large group of people to learn about how well these procedures work as a treatment for ulnar neuropathy at the elbow (UNE). Researchers want to see which surgery is more helpful for people with ulnar neuropathy. This research will determine if …

  • 0 views
  • 16 Feb, 2024
  • 10 locations
Vitamin K Supplementation Study in Healthy Volunteers (Aim 2B)

The overall purpose of this study is to determine how variation in the CYP4F2 gene modulates the synthesis of vitamin K-dependent clotting factors. We propose that the CYP4F23 gene variant increases short- and long-term vitamin K concentrations in the liver by reducing the efficiency of vitamin K metabolism. The investigators …

  • 0 views
  • 05 Aug, 2020
Naproxen Pharmacogenetic Study (Project 1 Aim 2)

This is a mechanism-based study in healthy adults to determine the effect of the CYP2C9 M1L gene polymorphism on the functional activity of the encoded CYP2C9 enzyme towards the probe substrate naproxen. CYP2C9 activity will be evaluated by measurement of O-desmethyl naproxen and unchanged naproxen in 24-hour urine following administration …

  • 0 views
  • 16 Feb, 2024
  • 1 location