Ruxolitinib for Acute Respiratory Disorder Syndrome Due to COVID-19
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- STATUS
- Recruiting
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- participants needed
- 200
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- sponsor
- Vanderson Geraldo Rocha
Summary
The COVID-19 pandemic has had a dramatic effect in public health worldwide. In Brazil, there have been more than 2 million confirmed cases and over 75,000 deaths since February 26, 2020. Based on reports of a hyperinflammatory state associated with COVID-19, the use of immunosuppressive drugs may be efficacious in the treatment of this disease. JAK inhibitors have been shown to harness inflammation in a number of different pathologic conditions. The aim of the present study is to evaluate the efficacy and safety of JAK inhibitor ruxolitinib in patients with acute respiratory distress syndrome due to COVID-19.
Details
Condition | Severe Acute Respiratory Syndrome Coronavirus 2, SARS-CoV2 |
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Age | 18years - 95years |
Treatment | Placebo, Janus Kinase Inhibitor (ruxolitinib) |
Clinical Study Identifier | NCT04477993 |
Sponsor | Vanderson Geraldo Rocha |
Last Modified on | 16 February 2024 |
How to participate?
Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.
Learn moreIf you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.
Learn moreComplete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.
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