Dual-scopic Pancreatic Necrosectomy (DPN)

  • STATUS
    Recruiting
  • End date
    Dec 31, 2025
  • participants needed
    20
  • sponsor
    First People's Hospital of Hangzhou
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Updated on 16 February 2024
See if I qualify
ct scan
cavity
abdominal pain
cavities
lipase
serum amylase
abdominal ct scan
cholecystectomy
colic
necrosectomy
stomach pain
normal saline
seldinger technique

Summary

The LPN procedure is performed under general anesthesia. The transperitoneal access to peripancreatic space is via the gastro-colic ligament and greater omentum, effusion and pus is removed by laparoscopic forceps and suction. Laparoscopic cholecystectomy (LC) is performed during the LPN procedure on patients with indication.

The NPN procedure is followed by the standard retroperitoneal approach. After the catheter is exchanged over a guide wire and serially dilated up from 6F to 24F followed by Seldinger technique, the access track to the necrotic cavity is established. A nephroscope is inserted into the cavity through the track for debridement. Using forceps and suction, the peripancreatic solid necrotic tissue and pus is grasped and removed. A large-bore irrigating drain is left in the cavity, with continuous irrigation by warm normal saline solution at a rate of 100-125 ml/h after surgery.

Details
Condition Pancreatitis, Pancreatitis, Pancreatic disorder, Necrotizing pancreatitis
Age 18years - 100years
Treatment Dual-scopic pancreatic necrosectomy（DPN）
Clinical Study IdentifierNCT04443595
SponsorFirst People's Hospital of Hangzhou
Last Modified on16 February 2024

Eligibility

 Yes No Not Sure

Inclusion Criteria

All patients ages 18 or above admitted to UPMC with a diagnosis of AP based on at least 2 of the following criteria:(i) abdominal pain characteristic of AP (ii) serum amylase and/or lipase 3 times the upper limit of normal (iii) characteristic findings of AP on abdominal CT scan will be screened for study enrollment

Exclusion Criteria

Less than 18 years of age
Pregnant women
Presence of renal dysfunction (Cr>1.5mg/dL)
Pre existing heart dysfunction or NYHA classification score above III
Coagulation disorder
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ct scan
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