Helmet CPAP Versus HFNC in COVID-19

  • STATUS
    Recruiting
  • participants needed
    120
  • sponsor
    Lund University
Send
Updated on 16 February 2024
See if I qualify
continuous positive airway pressure
hypoxia
oximetry
covid-19
SARS
respiratory failure
acute respiratory syndrome (sars)

Summary

We aim to investigate whether the use of Continuous Positive Airway Pressure using a Helmet device (Helmet CPAP) will increase the number of days alive and free of ventilator within 28 days compared to the use of a High Flow Nasal Cannula (HFNC) in patients admitted to Helsingborg Hospital, Sweden, suffering from COVID-19 and an acute hypoxic respiratory failure.

Description

A detailed description can be found in the study protocol which is pending submission for peer-review.

Details
Condition COVID, Acute Hypoxemic Respiratory Failure
Age 18years - 100years
Treatment HFNC, Helmet CPAP
Clinical Study IdentifierNCT04395807
SponsorLund University
Last Modified on16 February 2024

Eligibility

 Yes No Not Sure

Inclusion Criteria

Age 18 years
Sars-Cov-2 found in the upper or lower respiratory tract by PCR during the current disease episode
Peripheral oxygen saturation (SpO2) < 92 % despite conventional low-flow oxygen therapy of at least 6 L /min for at least 15 min
A decision to initiate HFNC or Helmet CPAP by the attending ward physician
The patient has given written informed consent to participate

Exclusion Criteria

Need for direct admission to the intensive care unit for mechanical ventilation
Unconsciousness or drowsiness
Pneumothorax
Carbon dioxide pressure (pCO2) > 6 kPa in venous blood gas (VBG)
Underlying chronic obstructive pulmonary disease stage III-IV
A decision not to participate
Inability to comprehend the study content and give informed consent
Clear my responses
Read more

How to participate?

Step 1 Connect with a study center
Message sent successfully.
We have submitted the information you provided to the research team at the location you chose. For your records, we have sent a copy of the message to your email address.
If you would like to be informed of other studies that may be of interest to you, you may sign up for Patient Notification Service.
Sign up

Send a message

Enter your contact details to connect with study team

Investigator Avatar

Primary Contact

First name*
Last name*
Email*
Phone number*
Other language

Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

Learn more

If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

Learn more

Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

Learn more

Similar trials to consider

Browse trials for

continuous positive airway pressure
hypoxia
oximetry
covid-19
SARS
respiratory failure
acute respiratory syndrome (sars)

Not finding what you're looking for?

Every year hundreds of thousands of volunteers step forward to participate in research. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.

Sign up as volunteer
Add a private note
  • abc Select a piece of text.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.