Efficacy of Narrow Band Spectrum Endoscopy for the Diagnosis of Gastric Antral Vascular Ectasia in Patients With Liver Cirrhosis

  • STATUS
    Recruiting
  • participants needed
    100
  • sponsor
    Alexandria University
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Updated on 16 February 2024
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Summary

the study aims to evaluate the role of similar technology of Narrow Band Imaging VIST video intelligent staining technology in the diagnosis of Gastric Antral Vascular ectasia in cirrhotic patients

Description

VIST (Video intelligent staining technology) is used to the diagnosis of GAVE as the form of ectatic vessels in the antrum in instead of erosions in the antrum by White light endoscopy which can mislead the diagnosis to Portal hypertension gastropathy. Targeted biopsies are taken and examined histopathologically in order to see if matching with VIST view. In addition, CD61 is used to highlight the diagnosis for more confirmation. CD61 is an immunohistochemistry platelets marker.

Details
Condition Gastric Antral Vascular Ectasia, Gastropathy, stomach discomfort, stomach discomfort
Age 18years - 100years
Treatment Upper gastrointestinal endoscopy and biopsy
Clinical Study IdentifierNCT04388150
SponsorAlexandria University
Last Modified on16 February 2024

Eligibility

 Yes No Not Sure

Inclusion Criteria

Patients with mucosal vascular lesions at the gastric antrum suspicious of GAVE of a linear striped form or a diffuse punctate form upon conventional WLE

Exclusion Criteria

Connective tissue disorders like systemic sclerosis
Chronic kidney disease
Recent use of proton pump inhibitors in the last 14 days
History of gastric surgery or gastric cancer
Pernicious anemia
Recent history of non-steroidal anti-inflammatory drugs intake
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