Umbilical Cord(UC)-Derived Mesenchymal Stem Cells(MSCs) Treatment for the 2019-novel Coronavirus(nCOV) Pneumonia

  • STATUS
    Recruiting
  • participants needed
    16
  • sponsor
    ZhiYong Peng
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Updated on 16 February 2024
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pneumonia
coronavirus infection

Summary

Serious Pneumonia and Critical Pneumonia caused by the 2019-nCOV infection greatly threats patients' life, UC-MSCs treatment has been proved to play a role in curing multiple diseases. And this study is conducted to find out whether or not it will function in 2019-nCOV infection Pneumonia.

Description

Serious Pneumonia and Critical Pneumonia caused by the 2019-nCOV infection greatly threats patients' life, UC-MSCs treatment has been proved to play a role in curing multiple diseases. And this study is conducted to find out whether or not it will function in 2019-nCOV infection Pneumonia. And we are going to get the permission of the enrolled patients. Besides the present clinical treatment, UC-MSCs treatment will be applied to those fulfilling the enrollment. After a period of UC-MSCs treatment, the analysis of UC-MSCs treatment will be completed from related aspects.

Details
Condition Ventilator associated pneumonia, Viral pneumonia
Age 18years - 80years
Treatment UC-MSCs
Clinical Study IdentifierNCT04269525
SponsorZhiYong Peng
Last Modified on16 February 2024

Eligibility

 Yes No Not Sure

Inclusion Criteria

-80 years old ,no gender restriction
According to Diagnosis and Clinical Management of Pneumonia caused by 2019-nCoV infection(Trial Version 6), patients are diagnosed with severe or critical 2019-nCoV pneumonia
Women of childbearing age should have a negative blood pregnancy test before the start of dosing and agree to take effective contraceptive measures during the trial until the last follow-up (28 days)
Previous detection of Nucleotide or antibody of 2019-nCoV pneumonia was positive
Voluntarily participate in this clinical study and sign a written informed consent. If the patient cannot obtain informed consent, he can authorize his legal representative

Exclusion Criteria

Liver SOFA score of more than 3 points
HIV positive
Highly allergic constitution or history of severe allergies
Pregnant and lactating women
Patients with malignant tumors
Patients with previous history of pulmonary embolism
Participating in clinical trials of other drugs within 3 months before enrollment
be thought by researchers to be inappropriate to participate in this clinical study
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