Progressive Resistance Training for Sarcoma Survivors

  • STATUS
    Recruiting
  • participants needed
    10
  • sponsor
    OHSU Knight Cancer Institute
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Updated on 16 February 2024
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cancer
sarcoma
fatigue
weakness
residual tumor
resistance training

Summary

This trial studies how well progressive resistance training works in improving the physical function of sarcoma survivors. Treatments for sarcoma can cause side effects such as fatigue, muscle loss, and weakness, which can negatively impact a patient's ability to physically function and enjoy an independent lifestyle. Engaging in a resistance training exercise routine may improve physical function, body composition, and bone density of sarcoma survivors.

Description

PRIMARY OBJECTIVE:

I. To determine the feasibility of a home-based individualized progressive resistance training (PRT) program in sarcoma survivors.

SECONDARY OBJECTIVES:

I. To assess secondary measures of feasibility of a home-based, individualized PRT program in sarcoma survivors.

II. To determine if a 3-month PRT program improves physical function in sarcoma survivors.

OUTLINE

Patients complete a series of progressive resistance training exercises at home twice weekly over 1 hour and receive instructional guidance from an exercise physiologist via videoconferencing once per week during one of these sessions for up to 12 weeks.

After completion of study, patients are followed up at 3 months.

Details
Condition Connective and Soft Tissue Neoplasm, Solid Tumors, Sarcoma, Sarcoma, Cancer Survivor, Solid Tumors
Age 15years - 100years
Treatment resistance training, Questionnaire Administration, Quality-of-Life Assessment, Exercise Counseling
Clinical Study IdentifierNCT04247425
SponsorOHSU Knight Cancer Institute
Last Modified on16 February 2024

Eligibility

 Yes No Not Sure

Inclusion Criteria

Eligible for the Sarcoma Survivorship Registry (Institutional Review Board [IRB] #12039)
History of histologically-confirmed sarcoma
History of treatment with surgery, radiation and/or chemotherapy for the sarcoma diagnosis
Completion of sarcoma treatment >= 2 years prior to study enrollment
No evidence of recurrent or residual disease on surveillance exam or imaging for at least 2 years prior to study enrollment
Sarcoma location must have been in the extremities, body wall, pelvic/shoulder girdle or axial skeleton. Intra-thoracic, intra-abdominal or cranial sarcomas are not eligible
Currently engaging in < 1 hour of resistance exercise per week by self-report. Examples of resistance exercise include: using free weights or weight machines, push-ups, sit-ups, lunges, plank, etc
Able and willing to commit to attending weekly video coaching sessions and independently completing weekly resistance training sessions. This requires access to internet and a device with video and audio capabilities. A webcam may be provided by the study to the participant if needed
Able and willing to commit to attending one initial in-person training session and one in-person follow-up assessment
Ability to understand and willingness to sign a written informed consent document

Exclusion Criteria

Medical contraindication(s) to any and all resistance training as determined by treating physician
Non-English speaking. At this time, we do not have resources to support translation of exercise physiologist (EP) sessions
Dependent on a mobility device (e.g., crutches, wheelchair) for independent activities of daily living (IADLs)
Use of a cane is permitted
Participant has known psychiatric or substance abuse disorders that would interfere with cooperation with the requirements of the trial
Any condition that, in the opinion of the investigator, would interfere with evaluation of study treatment or interpretation of participant safety or study results (e.g., pregnancy)
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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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