Verification of Predictive Biomarkers for Pancreatic Cancer Treatment Using Multicenter Liquid Biopsy

  • STATUS
    Recruiting
  • End date
    Dec 31, 2025
  • participants needed
    662
  • sponsor
    National Cancer Center, Korea
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Updated on 16 February 2024
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cancer
adenocarcinoma
cancer treatment
pancreatic adenocarcinoma
pancreatic cancer

Summary

This study is for verification of predictive biomarkers for pancreatic cancer treatment using multi-center liquid biopsy.

Description

Clinical applicability of KRAS mutations using circulating-tumor DNA in pancreatic cancer patients.

  • Quantification and monitoring of KRAS mutations Using droplet digital PCR in ctDNA extracted from collected patient samples.
  • Correlation analysis of KRAS mutation results with clinical data.

Discovery of biomarkers for predicting pancreatic cancer prognosis through ctDNA panel.

  • Gene panel composition for pancreatic cancer therapeutic target determination and monitoring.
  • A panel was performed using gDNA and ctDNA of tumor tissue collected from pancreatic cancer patients.
  • Comparative analysis of panel results and quantitative KRAS mutations and evaluation of clinical applicability.

Details
Condition Pancreas Adenocarcinoma
Age 100years or below
Clinical Study IdentifierNCT04241367
SponsorNational Cancer Center, Korea
Last Modified on16 February 2024

Eligibility

 Yes No Not Sure

Inclusion Criteria

Patients with pathologically confirmed pancreatic adenocarcinoma

Exclusion Criteria

Patients disagree with the study
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