A Prospective Cohort of Pulmonary Ground Glass Nodules Patients With Family History.

  • STATUS
    Recruiting
  • participants needed
    600
  • sponsor
    Guangdong Provincial People's Hospital
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Updated on 16 February 2024
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cancer
lung cancer

Summary

The aim of the present prospective cohort study (GGN-F) is to study the family aggregation of pulmonary ground glass nodules via the questionnaire survey and to investigate the underlying genetic mechanism via the biobank.

Description

In recent years, with the development of low-dose chest CT screening, more and more ground glass nodules have been found. Meanwhile, presenting as Ground-glass nodule (GGN), the early-stage lung adenocarcinoma patients with lung cancer family history have been emerging increasing in recent years in East Asian.

This prospective cohort study, with both a cross-sectional and a longitudinal part, will include patients with pulmonary ground glass nodule, which were proven malignant disease.

All participants will be asked to complete questionnaire to build the clinical database of GGN patients with detailed family history. Furthermore, blood and surgical tumor samples will be collected as a specific biobank. And the blood samples of other family members of participants will be collected, with their consent and knowledge.

Details
Condition Pulmonary Disease, Family, Lung Neoplasm
Age 100years or below
Clinical Study IdentifierNCT04220268
SponsorGuangdong Provincial People's Hospital
Last Modified on16 February 2024

Eligibility

 Yes No Not Sure

Inclusion Criteria

b'patients with informed consent;'
b'patients with pulmonary ground glass nodule.'
b'pathological proved early stage lung cancer.'

Exclusion Criteria

b'not included in the inclusion criteria'
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