KDIGO Bundle to Prevent AKI in Sepsis

  • STATUS
    Recruiting
  • participants needed
    100
  • sponsor
    Hospital General Universitario Elche
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Updated on 16 February 2024
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Summary

Summary: Controlled, prospective, randomized and randomized clinical trial of two intervention groups (standard care vs. preventive recommendations the Kidney Disease: Improving Global Outcomes (KDIGO) guidelines for AKI) of patients diagnosed with sepsis and abdominal post-surgical septic shock with positive results in the risk determination of acute renal injury by NephroCheck Test that integrates the urinary biomarkers TIMP-2 and IGFBP-7.

Hypothesis: The implementation of a package of preventive measures proposed by the KDIGO guide can reduce the occurrence and severity of acute renal injury in the high-risk abdominal post-surgical septic patient detected by urinary biomarkers for early detection.

Details
Condition Septic Acute Kidney Injury
Age 18years - 100years
Treatment Preventive recommendations for kidney disease: guidelines for improving overall outcomes (KDIGO) for AKI
Clinical Study IdentifierNCT04222361
SponsorHospital General Universitario Elche
Last Modified on16 February 2024

Eligibility

 Yes No Not Sure

Inclusion Criteria

Patients older than 18 years
Patients (or their informed family members) who accept and sign the informed consent
Patients diagnosed with sepsis or abdominal post-surgical septic shock

Exclusion Criteria

Patients under 18 years
Patients (or their authorized relatives) who refuse to sign the informed consent
Patients diagnosed with sepsis or non-surgical septic shock
Patients diagnosed with sepsis or septic shock of origin other than abdominal
Patients with AKI stages KDIGO 2 and 3 and / or renal replacement therapy
Patients with chronic renal failure and glomerular filtration <30 ml / min and / or undergoing treatment with dialysis or previous renal transplantation
Patients with AKI of origin other than the diagnosed septic, such as glomerulonephritis or interstitial nephritis, renal artery occlusion and / or postrenal obstruction
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