This study is currently not recruiting participants.

Precise Transplantation of Human Amniotic Epithelial Stem Cells Into Lateral Ventricle for Parkinson's Disease

  • STATUS
    Not Recruiting
  • participants needed
    18
  • sponsor
    Shanghai East Hospital
Updated on 12 February 2026
Online studies

Summary

This is a single-center, single-arm, dose escalation study, to explore the safety, tolerability and efficacy of human amniotic epithelial stem cells (hAESCs) for idiopathic Parkinson's disease (PD).

Description

hAESCs will be administration through the Ommaya reservoir implanted into the lateral ventricle of subjects with idiopathic PD.

This dose escalation will be followed by an exploratory expansion phase in 3 cohorts.

  • Dose A (5×10^7 cells/dose)
  • Dose B (1.0×10^8 cells/dose)
  • Dose C (1.5×10^8 cells/dose).

Details
Condition Idiopathic Parkinson's Disease
Age 40years - 70years
Clinical Study IdentifierNCT05691114
SponsorShanghai East Hospital
Last Modified on12 February 2026

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